Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
 31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An 82-year-old man presented with abdominal pain and a painful and swollen left thigh. On examination there was oedema, tenderness and crepitus with skin discoloration of the left thigh. Computed tomography showed retroperitoneal perforation of the caecum and necrotising fasciitis of the left thigh. A right hemicolectomy and repeated fasciotomies of the left thigh with debridement of necrotic tissue were performed but the patient died of multi-organ failure. Histology showed a pT4aN2c caecal adenocarcinoma. This is a unique presentation of a retroperitoneal caecal perforation and acts as a reminder that unexplained severe fasciitis of the thigh may be caused by an intra-abdominal pathology.
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PMID:Necrotising fasciitis of the left leg caused by perforated caecal adenocarcinoma. 2902 86

Necrotizing fasciitis are rare but often fatal conditions. A retroperitoneal origin is very rare and limited to case studies; very few cases have been reported in the literature. We report a case of 42-year-old man who presented with complaints of severe constipation and paraumbilical abdominal pain for the past three days. On examination, the abdomen was tender and distended, giving features of bowel obstruction. CT scan suggested perforated appendix. Subsequent exploration revealed retroperitoneal necrotizing fasciitis extending down to right testicular tissue. After extensive debridement and drain placement, the patient was admitted to the ICU where with intensive monitoring and aggressive daily dressing the patient survived. Necrotizing fasciitis of other anatomical sites are easier to diagnose as compared to retroperitoneal origin. Focus should be placed while dealing with cases of acute abdomen as early diagnosis and prompt surgical intervention is needed for successful treatment.
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PMID:Retroperitoneal necrotizing fasciitis in a 42-year-old male patient: A case report. 3315 70


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