Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0000737 (abdominal pain)
31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The sexual problems of 50 women with Crohn's disease, of whom 45 had a stable relationship, were investigated by structured interview and compared with age-matched controls. Twenty-four percent patients had either infrequent or no intercourse compared with 4% of controls (chi 2 = 8.3, p < 0.005). However, amongst patients and controls who were sexually active, the frequency of intercourse was similar. Reasons for sexual inactivity included abdominal pain (24%), diarrhoea (20%) and fear of faecal incontinence (14%). Dyspareunia was common in patients (chi 2 = 6.5, p < 0.01) and this was irrespective of the site of disease (large vs. small bowel chi 2 = 0.85, NS). Women with perianal disease and fistulae were more likely to have dyspareunia than women with neither (chi 2 = 4.2, p < 0.05), although this was not so for less extensive involvement with only perianal disease (chi 2 = 2.8, NS) or fistulae (chi 2 = 0.8, NS). Vaginal candidiasis was more common in patients (chi 2 = 5.8, p < 0.02), and on occasions this may have contributed to dyspareunia. Women with Crohn's disease experience sexual problems much more than healthy controls and they need support, sympathetic investigation and management.
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PMID:Sexual dysfunction amongst women with Crohn's disease: a hidden problem. 145 52

Retrospective review of 294 women who were sterilized by laparoscopy employing the falope ring during a 3-year period revealed complications in 2.7% of the cases. 2.5% became pregnant after the intervention. In more than 1/2 of the cases, this was due to incorrect placement of the ring. 21% experienced low abdominal pain postoperatively and 58% experienced menstrual changes. On the average, the patients felt well after 12 days; work was re-commenced after 3. Sexual activity was resumed after 14 days. Dyspareunia occurred in 6.5% of the cases and persisted, on an average, for 18 weeks. 14% experienced increased libido and 16% said they found greater sexual satisfaction. Nearly every 10th women (8.6%) regretted the procedure and 7% were dissatisfied with the cosmetic results. The frequency and predictability of complications, postoperative lower abdominal pain, and menstrual disturbances were similar in both a department of general surgery and a specialized gynecological unit. The duration of hospitalization, time spent convalescing, and duration of sick leave were considerably shorter than following sterilization by laparotomy and, in addition, sexual activity was resumed earlier. On the basis of this investigation, laparoscopic sterilization is recommended as a means of sterilization for women in departments of general surgery. (author's modified)
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PMID:[Sterilization of women using laparoscopy. A 3-year cohort]. 296 23

Endometriosis is a growth of endometrial tissue outside the uterine cavity which is responsive to hormonal stimulation. Extrapelvic endometriosis is less common of which skin is the most common site. The patient presents with mass, pain and cyclic symptoms. Subcutaneous endometriosis is very rare and has been reported only thrice in the literature. We report a case where the patient with lower abdominal pain and dyspareunia. Dyspareunia due to subcutaneous endometriosis has not been reported before when there is no evidence of intrapelvic endometriosis on laparoscopy.
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PMID:Subcutaneous endometriosis: a rare cause of deep dyspareunia. 2439 79