Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000737 (abdominal pain)
31,184 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

1159 patients underwent appendectomy via a McBurney incision from 1972 to 1983 at our institution. 115 patients (10%) had a mobile cecum syndrome (CMS) as defined by Nicole, without evidence of appendicitis or other pathologic findings at operation. 102 patients were followed up to 15 years after the operation. 82% of the 102 patients were free of symptoms at assessment. 36 patients underwent appendectomy and 63 appendectomy and cecopexy. The two cohorts were comparable with respect to sex, age at operation, duration of right lower abdominal pain, operative findings and length of follow-up. There was no significant difference in the postoperative result of patients with appendectomy alone and those with appendectomy and cecopexy. Moreover, we were not able to identify patients who may benefit from an additional cecopexy, on the basis of patient related factors or intraoperative findings.
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PMID:[The mobile cecum syndrome: appendectomy and cecopexy or only appendectomy?]. 272 4

Intestinal malrotation is a developmental anomaly that occasionally causes an unusual array of symptoms in adults. The delay in diagnosis that is common in patients with malrotation frequently results in a ruptured appendix. Appendicitis should be considered when characteristic signs and symptoms are present, even if the location of abdominal pain is atypical.
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PMID:Subhepatic appendicitis. 272 41

The total leucocyte count (TLC) and neutrophil percentage (NP) were studied prospectively in 1032 patients who underwent appendicectomy for suspected acute appendicitis. On histopathological study of the resected appendices, 97 patients had normal appendices, and 935 patients had acutely inflamed, gangrenous or perforated appendicitis. Statistically more patients with appendicitis had either raised TLC or raised NP compared with patients with normal appendices (P less than 0.001), and also compared with 357 patients who were admitted with right lower quadrant abdominal pain but were not subjected to operation (P less than 0.001). The sensitivity and specificity of raised TLC in diagnosing appendicitis for patients who underwent appendicectomy were 81.4% and 77.3%, respectively. Sensitivity increased when either raised TLC or raised NP were used, but specificity decreased. In contrast, sensitivity decreased when both raised TLC and raised NP were used together, but specificity increased. Raised TLC, preferably combined with raised NP, is a useful diagnostic aid in acute appendicitis. The TLC and NP, however, should only be interpreted in the light of physical findings in patients with suspected appendicitis because these blood tests have false positive and false negative results.
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PMID:Leucocyte count and neutrophil percentage in appendicectomy for suspected appendicitis. 273 Apr 58

Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. We reviewed our experience with 31 cases of Meckel's diverticulum in children from 1966 to 1987. Twenty-four patients presented with clinical manifestations: ten from bleeding, ten from obstruction, and four from diverticulitis. Seven Meckel's were incidental findings at laparotomy. Fifty percent of the patients with bleeding had abdominal pain and 100% had ectopic gastric mucosa in the Meckel's. In six cases the technetium scan identified the Meckel's; there was one false negative scan. Obstruction secondary to a Meckel's diverticulum was due to an internal hernia in five and to intussusception in five. Three patients with intussusception had concomitant bleeding. Diverticulitis was clinically similar to appendicitis. There were no complications and no deaths following surgical resection of Meckel's diverticulum.
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PMID:Meckel's diverticulum in the pediatric surgical population. 274 61

The two purposes of this study were to develop a clinical test of surgical resident proficiency and to compare this clinical test with currently applied methods of resident evaluation. Appendicitis is a common surgical disease, and its accurate diagnosis depends largely on clinical acumen. Ten third-year surgical residents prospectively evaluated 107 patients admitted because of suspected appendicitis. After taking a history, performing a physical examination, and reviewing laboratory data, these residents were asked to state, as a percentage, the likelihood that each patient had appendicitis. Sixty-three patients had appendicitis documented by pathologic inspection after appendectomy. Forty-four patients did not have appendicitis, as was determined by operation (17) or by in-house observation and resolution of abdominal pain (27). These outcomes were used to calculate a diagnostic ability score (DAS) for each resident. Residents were evaluated by standard methods including in-service examinations and monthly evaluations by the attending staff. Residents were also evaluated by nonstandard, but potentially useful, neuropsychologic and psychologic tests, including the trail making test, the Ravens progressive matrices test, the paced auditory serial addition test (PASAT), the grooved pegboard test of manual dexterity, and the profile of mood states (POMS) psychologic questionnaire. Cumulative scores were calculated and compared by multiple regression with coefficient variance analysis. The correlation (R2) of DAS with standard evaluation techniques was as follows: In-service (0.055), faculty (0.508), trails (-0.293), Ravens (0.028), PASAT (0.251), dexterity (0.432), POMS (0.381). We found that (1) the DAS is a discriminating clinical test; (2) the DAS correlates with subjective faculty evaluation; and (3) the DAS does not correlate with in-service examination scores. We conclude that faculty evaluation remains the best currently applied test of surgical resident clinical proficiency as measured by the DAS.
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PMID:The development and evaluation of a clinical test of surgical resident proficiency. 276 33

In a prospective 5-year investigation of acute appendicitis 603 consecutive patients with the disorder were studied in detail. Of this number 388 (64.3%) were female and 215 (35.7%) male giving a female: male ratio of 1.8:1. The patients were aged 4-65 years with a median age of 23.1 years; females with a median age of 22.1 years were younger than males with a median age of 25.4 years. Patients presented to hospital late: 3-7 days (median 5 days) from the onset of symptoms; the strikingly most common of these was abdominal pain seen in all the patients, and tenderness, local or with rebound was uniformly elicited. Supportive laboratory and radiological services were not regularly available; however, when white cell count was obtainable leucocytosis with a left shift was a useful finding. At operation 422 (70%) patients had an acutely inflamed appendix, 121 (20%) gangrenous or perforated appendicitis and 18 (3%) an appendix abscess; an appendix mass was palpable in 42 (7%) patients and these were treated conservatively. Wound infection complicated surgery in 18 (3%) patients; there were no operative deaths. Acute appendicitis was the second commonest surgical abdominal emergency during the period under study, and the results of treatment compare favourably with series from the developed countries of the West.
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PMID:Tropical surgical abdominal emergencies: acute appendicitis. 276 56

A retrospective study of 201 patients, 152 with simple and 49 with complicated, appendicitis is presented. Diagnosis of simple acute appendicitis was made on symptoms of abdominal pain, anorexia, nausea and vomiting, together with rebound abdominal tenderness and not on white blood cell count. Normal white blood cell count was found in 80.3% cases of simple acute appendicitis while elevated white cell count was associated with 85.7% of complicated appendicitis. There was no mortality in 152 patients who had appendectomies for uncomplicated acute appendicitis, but the mortality rate in the 49 patients with complications was 12.2%. This was responsible for the overall mortality rate of 3% for all appendectomies in this report. Complicated appendicitis in this review was largely due to pre-admission delays and the ingestion of strong cathartics, both of which could not be influenced by surgeons.
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PMID:Acute appendicitis: a clinical pattern in Port Harcourt Nigeria. 279 30

Adnexal torsion is rare in children and is usually reported as small series or case reports. We reviewed a series of 19 consecutive cases of children aged 3 to 19 years (mean, 9.6 years) who were treated in our institution between 1977 and 1988. Thirteen patients presented with torsion of a previously normal adnexa, while six presented with torsion of a diseased adnexa. The right adnexa was involved in 84% of cases. Detorsion with recovery of vascularization of the adnexa was possible in only four cases. All patients presented with lower abdominal pain, and onset was sudden in 78% of cases with an average of 5.2 days between the first symptom and hospital admission and a mean delay of 30.2 hours between consultation and surgical intervention. A previous history of abdominal pain was present in nine cases. Nausea or vomiting were present in 84% of cases. An abdominal mass was palpable in 42% of the patients and was associated with a delay in surgical intervention. Ultrasound confirmed the presence of a mass in 94% of cases. The preoperative diagnosis was accurate in 37% of cases, and the most common inaccurate diagnosis was appendicitis or appendiceal abcess. Our series confirms the predominance of right-sided lesions as reported in the literature. It is not clear whether this is an anatomic phenomenon or whether the suspicion of appendicitis leads to the more frequent diagnosis of right-sided lesions, whereas many left-sided adnexal torsions are being missed. We therefore advocate pelvic ultrasound in female patients who present with left lower quadrant pain.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Adnexal torsion in children. 280 69

During the 5-year period 1976-1980, seven cases of emergent surgical disease of the adnexae during pregnancy were encountered. The incidence of 1:1832 deliveries approximated that of appendicitis (1:1603 deliveries) during the same period. There were three cases of adnexal torsion, two ruptured ovarian cysts with hemorrhage, one heterotopic pregnancy, and one ruptured endometrioma. The right side was more commonly the site of the pathology, and abdominal pain the only consistent presenting symptom. Fever, tachycardia, and leukocytosis were inconsistent findings. Culdocentesis was positive in two cases. Four desired pregnancies were carried successfully to term postoperatively. Surgical emergencies of the adnexae will be encountered during pregnancy more commonly than is generally recognized. Aspects of obstetric management are described. If prompt surgical intervention is undertaken in pregnancy when the clinical picture suggests an acute abdomen, a satisfactory outcome can be expected.
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PMID:Surgical emergencies of the uterine adnexae during pregnancy. 288 Jul 65

The outcome was examined for 196 cases of urgent appendectomy in patients with abdominal pain and right lower quadrant tenderness and signs of peritoneal irritation. Appendicitis was found in 94 percent, and there was a 6 percent negative appendectomy rate. There were no complications among the patients with normal appendixes. Complications among cases of appendicitis compared favorably with other published series.
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PMID:Results of urgent appendectomy for right lower quadrant tenderness. 292 67


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