Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0000729 (abdominal cramps)
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Human Gene/Protein
B7A 10.6
TRAF4 9.3
P-B 9.1
BCO 9.1
LPI 8.8
GTS 7.9
HUS 7.9
TNFRSF1A 7.9
coagulation factor V 7.9
STEP 7.4
inosine monophosphate dehydrogenase 7.3
H21 6.9
MEFV 6.8
pseudocholinesterase 6.8
SIL 6.7
5-HT2B 6.6
HC1 6.5
SMS 6.4
castor 6.4
FACT 6.4
Cholinesterase 6.4
cGMP phosphodiesterase 6.4
SST 6.3
prune 6.3
HCG 6.1
NAG 6.1
granulocyte colony stimulating factor 6.1
ECL 6.0
myelo 5.9
thymidine phosphorylase 5.8
SMD 5.8
Growth hormone 5.7
CYP3A5 5.7
SMC 5.7
TSK 5.7
PRP 5.5
quinone oxidoreductase 5.5
muscarinic acetylcholine receptor 5.4
A-II 5.4
interferon alpha 5.3
trip 5.3
C1 inhibitor 5.1
SSA 5.1
soluble guanylyl cyclase 5.0
cholecystokinin 5.0
somatostatin 5.0
DNA binding protein 5.0
AST 4.9
lactase 4.8
NIDDM 4.7
guanylyl cyclase 4.7
endostatin 4.7
tap 4.7
CD57 4.7
EMA 4.7
CD23 4.7
GPT 4.6
hemochromatosis 4.6
CB2 4.5
CTX 4.4
chromogranin A 4.3
factor VII 4.3
porin 4.3
CYP3A4 4.2
gastrin 4.2
CYP3A 4.1
CCK 4.0
topoisomerase I 4.0
Spin 3.9
proton pump 3.9
She 3.9
CYP1A2 3.9
TNF receptor 3.8
GMP 3.7
vasoactive intestinal peptide 3.6
CB1 3.6
H. influenzae 3.6
CHOP 3.5
Tumor necrosis factor 3.4
C-reactive protein 3.3
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Disease
Phagophobia 13.6
Mechanical intestinal obstruction 13.3
Uremic syndrome 12.4
Norwalk gastroenteritis 11.8
Hemorrhagic colitis 11.8
nervous breakdown 11.5
Intestinal microsporidiosis 11.4
Clostridium perfringens food poisoning 11.3
ameboma 10.8
Withdrawal bleeding 10.7
oxyuriasis 10.3
small bowel lymphoma 10.0
Traveler's diarrhea 9.9
Immunoproliferative small intestinal disease 9.8
chafing 9.8
hemolytic jaundice 9.6
scrofula 9.5
Salmonella enteritis 9.5
hypotension and shock 9.4
E. coli septicemia 9.4
infectious gastroenteritis 9.3
cryptitis 9.3
Primary dysmenorrhea 9.2
erythrodermia 9.2
leukonychia 9.1
Collagenous colitis 9.1
Achilles tendinitis 9.0
Giardia infections 9.0
Campylobacter enteritis 8.9
Macrophage activation syndrome 8.8
aerophagia 8.8
enterolith 8.8
Amniotic fluid embolism 8.8
Mixed infection 8.7
giardiasis 8.7
Amniotic fluid embolism 8.7
polysubstance abuse 8.7
familial hypertriglyceridemia 8.6
threatened abortion 8.5
mesenteric thrombosis 8.4
Clostridium difficile colitis 8.4
pseudomembranous colitis 8.4
spirochetosis 8.4
hyperproteinemia 8.4
LPI 8.4
ischemic colitis 8.3
cryptosporidiosis 8.2
bacillary dysentery 8.1
dumping syndrome 8.1
CLL/SLL 8.1
thalassemia minor 8.1
infectious colitis 8.1
enterobiasis 8.1
bacterial diarrhea 8.1
proctocolitis 8.1
fear of cancer 8.0
Acute disseminated encephalomyelitis 8.0
parasympathomimetic 8.0
Systemic mastocytosis 8.0
hypoprothrombinemia 7.9
vascular headache 7.9
Shigella sonnei 7.7
evaluable disease 7.7
Mastocytosis 7.6
Intestinal ischemia 7.6
gastroenteritis 7.5
Waldeyer's ring 7.4
urticaria pigmentosa 7.4
lactose intolerance 7.4
dysentery 7.4
gastric retention 7.3
regional enteritis 7.3
agammaglobulinemia 7.3
megacolon 7.2
Eosinophilia 7.2
hemolytic uremic syndrome 7.2
Shigella 7.1
ileus 7.1
microsporidiosis 7.0
gastroparesis 7.0
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Symptom
abdominal cramps 15.9
Scrotal pain 11.3
cold sweats 11.1
Intermenstrual bleeding 10.9
Watery diarrhea 10.8
stomach cramps 10.3
tenesmus 10.1
Severe diarrhea 10.1
bloating 9.3
Visceral pain 9.0
Wind 9.0
leg cramps 8.7
nausea 8.5
frequent urination 8.5
diarrhea 8.4
Neurologic symptoms 8.3
prostration 8.3
vomiting 8.2
belching 8.2
tonic seizure 8.2
chronic constipation 7.9
dark urine 7.7
irregular bleeding 7.3
constipation 7.3
night sweats 7.2
intestinal bleeding 7.2
abdominal fullness 7.2
blurred vision 7.2
chills 7.1
dizziness 7.0
stomach pain 6.9
lightheadedness 6.9
ataxic gait 6.8
retching 6.8
excessive sweating 6.7
Gastrointestinal symptoms 6.7
myalgia 6.7
neck stiffness 6.6
hot flushes 6.6
pallor 6.6
tingling 6.6
tonic-clonic seizure 6.5
forgetfulness 6.5
nausea and vomiting 6.4
heartburn 6.4
flushing 6.4
anorexia 6.3
photophobia 6.2
rigors 6.2
asthenia 6.1
muscle cramps 6.1
oliguria 6.0
headache 6.0
paresthesia 5.9
polyuria 5.9
hypersomnia 5.8
colic 5.8
hot flashes 5.8
Ill 5.7
rhinorrhea 5.7
abdominal pain 5.6
sore throat 5.4
discomfort 5.4
discomfort 5.3
wheezing 5.2
enuresis 5.2
epigastric pain 5.1
abdominal discomfort 5.1
insomnia 5.1
arthralgia 5.1
sneezing 5.0
acute abdominal pain 4.9
polydipsia 4.8
weakness 4.7
vertigo 4.7
back pain 4.6
dysuria 4.6
fatigue 4.5
knee pain 4.4
hunger 4.4
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Drug
Trimoprostil 12.3
Sodium picosulfate 12.3
Zomepirac sodium 11.9
Ticlopidine hydrochloride 11.2
Imodium 11.0
Peanut oil 10.8
Buscopan 10.6
Imodium 10.6
Pancrease 10.5
Gemeprost 10.4
Rioprostil 10.4
Pancreatin 10.1
LVFX 10.0
Giardiasis 9.6
Poudre 9.0
Sulprostone 8.9
Nitazoxanide 8.6
Senna 8.5
Podophyllum 8.5
Cisapride 8.5
Salmon calcitonin 8.4
Voltaren 7.9
Cidofovir 7.8
Silica gel 7.7
Senna 7.6
Auranofin 7.5
Mycophenolic acid 7.4
Lugol 7.2
Diclofenac sodium 7.1
Misoprostol 6.8
Donepezil 6.8
Papain 6.7
Triad 6.6
CPT-11 6.6
Scopolamine 6.5
Irinotecan 6.2
Atropine 6.2
HCG 6.1
Omeprazole 5.9
Lactose 5.7
Azithromycin 5.6
Arsenic trioxide 5.6
ampicillin 5.4
Vitamin K 5.4
Prednisolone 5.3
Growth hormone 5.3
Growth hormone 5.3
Kenyan 5.1
NAG 4.8
CTX 4.4
Ringer's solution 4.4
CTX 4.4
CTX 4.1
EE2 3.9
ENT 3.8
ROC 3.0
lactose 2.8
nitroglycerin 2.8
Ethanol 2.6
citric acid 2.6
Leaf 2.5
caffeine 1.5
NADH 1.5
IL-2 1.0
lysine 1.0
CSF 1.0
Dermatol 0.2
Enzyme
lysine decarboxylase 7.2
chymopapain 7.2
chymopapain 7.1
SST 6.3
IMP dehydrogenase 6.0
cGMP phosphodiesterase 6.0
thymidine phosphorylase 5.9
lysin 5.8
ricin 5.8
BMT 5.5
AST 4.9
lactase 4.8
cholinesterase 4.2
CYP3A4 4.2
aspartate aminotransferase 3.5
papain 3.2
alanine aminotransferase 3.2
beta-glucuronidase 3.0
guanylate cyclase 2.8
acetylcholinesterase 2.7
alkaline phosphatase 2.6
glutathione S-transferase 2.4
thromboplastin 2.2
P-glycoprotein 2.2
thrombin 0.8
caspase-3 0.7
catalase 0.1
superoxide dismutase 0.0
peroxidase -0.1
ERK -0.7
mitogen-activated protein kinase -0.7
Compound
Sodium picosulfate 12.6
Indicaxanthin 12.2
Ricinine 11.7
Geranial 11.5
Dicyclomine 11.3
Dolasetron 10.6
tropic acid 10.3
Loperamide 9.9
Trisodium phosphate 9.7
Umbelliferone 9.3
ONT 9.1
C 10 8.7
butyramide 8.7
C 10 8.7
Cisapride 8.5
Pyridostigmine 8.5
Neostigmine 8.3
MK-329 8.2
Domoic acid 8.2
Citral 8.1
Geigy 8.0
Cidofovir 7.9
Mycophenolate mofetil 7.7
Mecamylamine 7.6
Alprazolam 7.6
Octreotide 7.5
Meperidine 7.5
Clotrimazole 7.4
Cotinine 7.4
Ticlopidine 7.4
Acarbose 7.4
SN-38 7.3
Desmopressin 7.3
2,3-dimercaptosuccinic acid 7.3
Pentagastrin 7.2
Sulfasalazine 7.0
Hexamethonium 7.0
Paroxetine 6.9
H-3 6.9
Organon 6.7
Toluidine blue 6.6
CPT-11 6.6
Clarithromycin 6.5
Menadione 6.3
Sorbitol 6.3
Levamisole 6.3
Atropine 6.2
HMM 6.2
Azithromycin 6.0
Bordeaux 6.0
Minocycline 6.0
Silymarin 5.9
Naltrexone 5.9
Azathioprine 5.9
Valproic acid 5.9
Colchicine 5.9
RU-486 5.8
Amoxicillin 5.8
protocatechuate 5.7
Lactose 5.7
Vitamin K 5.6
Omeprazole 5.6
prostaglandin E1 5.6
SEE 5.6
Capsaicin 5.5
TTS 5.5
Prednisolone 5.4
barium 5.3
Tetrodotoxin 5.3
boric acid 5.0
A 71 4.8
MBC 4.8
MBC 4.7
Ketamine 4.7
GPT 4.6
MTS 4.5
CIT 4.5
benzamide 4.3
Valproic acid 4.1
CTX 4.1
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