Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0000729 (
abdominal cramps
)
531
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Medication errors are probably more common in neonates than is generally appreciated. In Mexican pediatric hospitals,
L-carnitine
is mainly used for nutritional support and to treat cardiomyopathy secondary to neonatal asphyxia. Using a longitudinal-retrospective approach we assessed the appropriateness of all
L-carnitine
prescriptions written during a 12-month period at a NICU of a second-level hospital located in Toluca, Mexico. Reports of adverse reactions possibly related to
L-carnitine
therapy were collected and characterized. Overall, administration of
L-carnitine
was considered justified and appropriate only in 18% of patients. 60.7% of
L-carnitine
prescriptions were rated as inappropriate because the prescribed doses fell outside the recommendations. The overall rate of ADRs calculated from the patient population was 18.03%. All of them were of gastrointestinal type:
abdominal cramps
(8 cases, 61.54%) and vomiting (5 cases, 38.46%). Our results supported the establishment of an
L-carnitine
rational use policy at the NICU of the hospital under study.
...
PMID:Nutritional support and cardioprotection with L-carnitine: prescription appropriateness and safety concerns in Mexican neonates. 2147 8
