Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000729 (abdominal cramps)
 531 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An outbreak of Gnathostoma larva migrans occurred among guests of a New Year's party in Chachoengsao, Thailand. Nine people who consumed a raw fish dish called 'Hu-sae' contracted the disease. Five of them developed gastro-intestinal symptoms consisting of nausea, vomiting, abdominal cramps and diarrhea as early as within the first 24 hours, while in the other four, symptoms started on the following day. After the initial symptoms pertaining to the gut, malaise, chest discomfort, cough, myalgia, weakness, itching and migratory swellings were experienced. Eosinophilia was demonstrated in every patient with a mean (+/- SE) count of 5,516 +/- 1,010 cells/cu mm. Detection of antibody against aqueous extracts of G. spinigerum adult antigen using an enzyme-linked immunosorbent assay showed a titer of 1:1,600 or greater in every patients except one who had a titer of 1:400 (positive greater than or equal to 1:400). This outbreak illustrates the high attack rate when heavily infected fish are consumed.
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PMID:Gnathostoma larva migrans among guests of a New Year party. 182 91

Eosinophilia and intestinal infections with a trematode parasite developed in 18 of the 20 American tourists who traveled to Kenya and Tanzania; the fact that the two other tourists also had eosinophilia suggested that they too had been infested. Because no adult flukes were recovered, a specific identification could not be made, but the eggs we observed resembled those of an Echinostoma. Several tour members had mild, nonspecific abdominal complaints, but ten had moderately severe abdominal cramps and loose or watery stools. Treatment with praziquantel was associated with rapid symptomatic improvement, and after treatment no parasitic eggs were recovered from patients' stools.
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PMID:Outbreak of parasitic gastroenteritis among travelers returning from Africa. 407 36

A 56 years old swiss man suffers of recurrent abdominal cramps with episodes of diarrhea and profuse expectorations. The routine laboratory shows principally a massive eosinophilia and elevated IgE in peripheral blood. After excluding the most frequent causes of eosinophilia, further laboratory investigations shows increased levels antinuclear and anti-SSA antibodies, elevated IgG4, increased pancreatic amylase and intestinal eosinophilia. We consider two etiologies: the hypereosinophilic syndrome, diagnostic of exclusion, and the autoimmune pancreatitis. Although we have not sufficient arguments in favour of an autoimmune pancreatitis, these two entities present some similar points.
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PMID:[Abdominal pain, indigestion and eosinophilia]. 1660 77

Systemic mastocytosis (SM) is a rare clonal disorder of mast cells that can range from chronic smouldering type to aggressive mast cell leukaemia. It presents with non-specific symptoms like urticaria pigmentosa, unexplained flushing, hypotension and abdominal cramps, which may lead to a misdiagnosis, if there is no high index of clinical suspicion. This is a case report of a 52-year-old lady, with systemic mastocytosis, who presented with severe chronic back ache and no other clinical features. X - ray revealed lytic lesions in the lumbar vertebrae and bone marrow aspiration and a trephine biopsy examination showed infiltration by mast cells, with a positivity for Toluidine blue stain and CD 117. She was also noted to have peripheral eosinophilia, which is frequently encountered with this condition. She was diagnosed to have chronic indolent systemic mastocytosis which involved the bone predominantly.
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PMID:Systemic mastocytosis: predominantly involving the bone, a case report. 2429 98