Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000729 (abdominal cramps)
 531 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Withdrawal bleeding and other side effects such as edema, bloating, premenstrual irritability, lower abdominal cramps, dysmenorrhea, and breast tenderness limit compliance with hormonal replacement therapy. Although many of these troublesome side effects can be managed by adjusting the dose or changing the source of the estrogen or progestin components, postmenopausal women view withdrawal bleeding as the most negative factor influencing their decision to use hormonal replacement therapy. Additionally, the potential link between postmenopausal estrogen use and subsequent endometrial hyperplasia and cancer concerns potential users. Cyclic progestins protect the endometrium from hyperplastic changes but may not prevent withdrawal bleeding. Both patient and physician education, including the nature of menopause and the protective role of estrogens in osteoporosis and cardiovascular disease, are critical to improving compliance with hormonal replacement therapy.
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PMID:Compliance considerations with estrogen replacement: withdrawal bleeding and other factors. 269 Jun 38

Ischemic colitis has been associated with advanced age, cardiovascular disease, drug therapy and vascular surgery. It is an uncommon condition in the general population, but we think that not all cases are being recognized. These three patients, over 70 years old, were admitted with abdominal cramps and mild lower digestive bleeding . Clinical suspicion and early use of colonoscopy was helpful to establish the diagnosis. In these cases the recovery was uneventful, but in some others, severe complications and mortality can occur.
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PMID:[Ischemic colitis. Presentation of three cases and review of literature]. 1825 74