Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000727 (acute abdomen)
 3,084 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This prospective study comprises 651 patients with knife wounds of the anterior abdomen. Three hundred and forty-five patients (53%) had symptoms of an acute abdomen on admission and were operated on immediately. The remaining 306 patients (47%) were managed conservatively with serial clinical examinations. This group included 26 patients with omental or intestinal evisceration, 18 patients with air under the diaphragm, 12 patients with blood found on abdominal paracentesis, and 18 patients with shock on admission. Only 11 patients (3.6%) needed subsequent operation, and there was no mortality. The overall incidence of unnecessary laparotomies was 5% (completely negative, 3%). Of the 467 patients with proven peritoneal penetration, 27.6% had no significant intra-abdominal injury. It is concluded that many abdominal stab wounds can safely be managed without operation. The decision to operate or observe can be made exclusively on clinical criteria. Peritoneal penetration, air under the diaphragm, evisceration of omentum or bowel, blood found on abdominal paracentesis, and shock on admission are not absolute indications for surgery. Alcohol consumption by the patient does not interfere with the clinical assessment.
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PMID:Indications for operation in abdominal stab wounds. A prospective study of 651 patients. 381 86

We describe a case of a 51-year-old man who ingested methylene chloride and presented with the classical clinical features. He developed an acute abdomen that required repeated laparotomy. The effect of an ethanol infusion on carboxyhaemoglobin concentrations in this case was also of interest and could potentially be a new treatment modality.
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PMID:A case of methylene chloride poisoning due to ingestion of home-distilled alcohol and potential new treatment with ethanol infusion. 2240 64

A 78-year-old man with hepatocellular carcinoma treated by chemoembolization and percutaneous ethanol injection was admitted to our hospital because of acute abdomen. The CT scan showed biliary fistula caused by hepatocellular carcinoma protruding from S3. Endoscopic retrograde cholangiopancreatography showed disruption of an intrahepatic duct and the main pancreatic duct, and contrast agent leaked into the peritoneal cavity from each duct. Omental panniculitis with biliary fistula and pancreatic fistula was diagnosed. The symptoms improved by endoscopic nasobiliary drainage and endoscopic pancreatic stenting. On the 13th day after admission, we added endoscopic nasopancreatic drainage because his abdominal pain had been exacerbated by pancreatic juice leakage. Omental panniculitis by hepatocellular carcinoma complicated by biliary fistula and pancreatic fistula is extremely rare. Endoscopic transpapillary pancreaticobiliary drainage was effective for omental panniculitis in this case.
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PMID:[Successful endoscopic transpapillary pancreaticobiliary drainage for omental panniculitis by hepatocellular carcinoma complicated by biliary fistula and pancreatic fistula]. 2279 Jun 30