Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000727 (acute abdomen)
 3,084 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 42-yr-old woman with long-standing ulcerative colitis of the descending colon, sigmoid, and rectum presented with bloody diarrhea, tenesmus, and high fever. Endoscopic findings were compatible with an acute attack of ulcerative colitis, which proved to be resistant to systemic corticosteroid treatment. In the presence of an acute abdomen with ascites and double-contoured colonic wall, hemicolectomy was performed. Postoperatively, high temperature, hyponatremia, and elevated liver enzyme levels persisted. Pleural effusions developed. Antibodies to Legionella pneumophila serogroup 3 were detected in the serum. Erythromycin therapy induced rapid improvement. In a massive submucosal edema of the affected colon, L. pneumophila of the same serogroup was demonstrated by direct immunofluorescence staining.
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PMID:Legionella infection of the colon presenting as acute attack of ulcerative colitis. 231 72

Pneumatosis cystoides intestinalis is an uncommon condition characterised by multiple gas-filled cysts within the small intestine or colonic wall. Clinical manifestations are unspecific and often found in many other abdominal diseases. To avoid unnecessary laparotomy, radiologic and endoscopic findings are essential to be known. The present case associates symptoms highly suspect of neoplasia like weight loss, rectal mass, bloody stools and tenesmus. Treatment of choice is medical. In the absence of an acute abdomen, surgery is only reserved when it is not responsive to medical treatment.
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PMID:[Pneumatosis cystoides intestinalis. Diagnostic elements and therapeutic approach]. 1086 47

4 cases of extrauterine pregnancy with IUDs were studied both clinically and pathologically at the Faculty of Medicine of Ain Shams University in Cairo, Egypt. In 3 cases the gestation sac was tubal, with 2 in the ampullary portion and 1 in the isthmic portion. The 4th case was a left tubo-ovarian mass, showing an embryo within an ovarian gestation sac. Microscopic examination of the tube revealed chorionic villi intermingled with areas of necrosis, hemorrhage, and inflammatory cell infiltration. The diagnosis of the ovarian pregnancy was based on the demonstration of chorionic villi in relation to the ovarian medullary portion, showing a loose connective tissue structure and prominent congested blood vessels. Case 1, a 27-year old, para 2+0, presented with pain, amenorrhea, bleeding, and fever. The clinical diagnosis was septic abortion with IUD in situ. The loop was removed and curettage was scanty. Antibiotics were administered. The fever subsided but the abdominal pain persisted and mass in the right adnexa could be felt. Laparoscopy was performed, confirming the diagnosis of right tubal pregnancy. Laparotomy and right salpingectomy were performed. The 2nd case, para 1+0, had an IUD for 1 year and was admitted as an emergency. The diagnosis was acute abdomen, mostly disturbed ectopic pregnancy. Laparotomy was performed, and ectopic pregnancy in the region of the isthmus of the right tube was diagnosed. Right salpingectomy was performed. Both cases 3 and 4 had IUDs for a period of between 1-2 years and had amenorrhea, bleeding, and tenesmus. They were treated as colitis. The amenorrhea ranged between 2-3 months. Examination revealed a mass on the left side. Laparotomy was performed. In case 3 it was ampullary pregnancy on the left side. In case 4 there was a tubo-ovarian mass with an amniotic sac protruding from this mass. Left salpingo-oophorectomy was performed. All patients had uneventful recoveries. Figures illustrate these tubal and ovarian pregnancies.
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PMID:Ectopic pregnancy in patients using intrauterine contraception. 1227 56

Treatment of acute colorectal malignant obstruction, by using self-expandable metallic stents is useful for both palliative and decompressive therapy before the final surgical treatment. In this case, the patient may be benefit from a period of medical optimization prior to undergoing planned surgical resection by a colorectal surgeon. This is a minimally invasive procedure, relatively safe, which obviates the need for colostomy for evacuation relieving physical and psychological burden and contributing the improvement of quality of life. Furthermore, this method also has the advantage of being cost-effective. The previous experience in the benign biliary stenosis allowed the extension of using the metallic stents also for the treatment of benign colorectal diseases (diverticular occlusion, anastomotic strictures, colonic endometriosis). Complications of colon self-expandable metallic stents placement may occur during the procedure and soon after placement (early complications) or, rarely, late after insertion (late complications). These include bleeding, re-obstruction, pain, tenesmus, stent migration, and perforation. The authors report a case of an 81 year-old woman with inoperable rectal carcinoma with liver metastasis who underwent palliative treatment of self-expanding metallic stent endoscopic placement. One month later, the patient presented with acute abdomen at Accidents and Emergencies Department. The diagnosis was a late rectosigmoid junction perforation by stent placement.
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PMID:[Late complication after colon self-expandable metal stent placement: a case report]. 1728 98