Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000727 (acute abdomen)
 3,084 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 47-year-old man presented with backache and signs of acute abdomen. An exploratory laparotomy was performed. Post-operatively he developed hypoxaemia in the operating theatre and was brought to the Surgical Intensive Care Unit for ventilatory support and further investigations. History was then retaken and revealed a minor foot injury one month ago with subsequent development of muscle spasm and dysphagia. The diagnosis of tetanus was made. The patient was then treated with human antitetanus immune globulin and crystalline penicillin. Ventilatory support was continued, aided by infusion of morphine, diazepam and alcuronium. The recovery course was complicated by chest infection, urinary tract infection and sympathetic overactivity. He improved later and ventilatory support was discontinued three weeks after admission. He then made uneventful recovery and was discharged from the hospital forty days after admission.
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PMID:A case of tetanus mimicking acute abdomen. 776 95

We report a case of abdominal pain with rigidity, mimicking an acute abdomen, caused by metoclopramide, a common anti-emetic drug. Extrapyramidal symptoms are commonly reported side-effects of this medication. They generally include involuntary movements of limbs, torticollis, oculogyric crisis, rhythmic protrusion of tongue, trismus, or dystonic reactions resembling tetanus, etc. Abdominal rigidity due to this medication, resembling an acute abdomen, has not been reported previously. This case report illustrates the importance of considering medication side-effects when evaluating a patient with abdominal pain and rigidity.
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PMID:Abdominal pain with rigidity secondary to the anti-emetic drug metoclopramide. 1674 Apr 51

Tetanus is still a difficult-to-treat disease with high morbidity and mortality. Although it most commonly occurs in non-immunized children, it can also be seen in partially immunized or immunized children. We report herein two pediatric cases of generalized tetanus. Case 1 presented with signs of acute abdomen, while Case 2 presented with the typical clinical findings of tetanus. In this report, we highlight the importance of obtaining a history of the vaccination status of pediatric patients as an essential part of the evaluation. Furthermore, the differential diagnosis of non-immunized children with abdominal rigidity should include generalized tetanus.
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PMID:A report of two pediatric tetanus cases. 2198 Aug 47