Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000727 (acute abdomen)
 3,084 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In female patients affected by congenital coagulation disorders haemorrhagic corpus luteum must be considered for the differential diagnosis of acute abdomen. We report the complication in a 22-year-old woman with type 3 von Willebrand's disease who presented with abdominal pain and haemorrhagic shock. Along with adequate factor VIII replacement therapy oral contraceptive treatment is the key for the management of this potentially life-threatening complication and the long-term prevention of future bleeding episodes of this origin.
Haemophilia 1998 Jan
PMID:Haemoperitoneum caused by haemorrhagic corpus luteum in a patient with type 3 von Willebrand's disease. 987 87

Splenic lymphangiomas are benign neoplasms resulting from congenital malformations of lymphatic channels manifesting as cystic lesions, occurring mostly in childhood. This process usually involves additional sites in a diffuse or multifocal fashion but although rare, can also present isolated to the spleen. The clinical picture varies from asymptomatic identified incidentally to nonspecific symptoms from compression of adjacent organs. Spontaneous rupture of these lesions can lead to hemoperitoneum, acute abdomen and hemorrhagic shock. We present the case of a 33-year-old male who required urgent exploration and splenectomy secondary to ruptured splenic lymphangioma, complicated by postoperative bleeding, re-exploration and blood transfusion from unknown Hemophilia A. Overall, it is important to be cognizant of this condition in the setting of left upper quadrant pain, even in an adult, as any delay in diagnosis or treatment can lead to life-threatening complication.
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PMID:A rare case of spontaneous splenic rupture complicated by hemophilia A. 3163 85