Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0000727 (acute abdomen)
3,084 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The association between Clostridium septicum sepsis in patients with malignant disease has been frequently documented. A presentation with fever, neutropenia, vomiting, and an acute abdomen is characteristic of this anaerobic infection which has been uniformly fatal in children with acute leukemia. We report the unusual course and the successful treatment of an adolescent with an abdominal Burkitt's lymphoma with leukemic transformation and clostridium septicum sepsis and cellulitis.
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PMID:Successful therapy of Clostridium septicum sepsis in a child with Burkitt's lymphoma. 678 26

We present the radiological and clinical aspects of a patient with advanced-stage Burkitt lymphoma who presented with an acute abdomen complicated by abdominal compartment syndrome.
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PMID:Abdominal compartment syndrome in a newly diagnosed patient with Burkitt lymphoma. 1639 47

Primary appendiceal Burkitt lymphomas are rare occurring in 0.015% of all gastrointestinal lymphomas. Presentation of such lymphomas with peritonitis and obstructive jaundice owing to its subhepatic location is even more unusual. Burkitt lymphoma is very rare in children below 5 years old. We will present a 3-year-old boy with primary appendiceal lymphoma whose first symptom was obstructive jaundice caused by a ruptured retrocecal subhepatic appendix which in essence is a combination of all 3 mentioned occurrences complicated with acute abdomen.
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PMID:Nonendemic Burkitt lymphoma presenting with an atypical clinical picture. 1780 48

Leukemic and lymphomatous involvement of the appendix is rare and even rarer is its presentation as appendicitis. Burkitt's lymphoma is a high grade B-cell neoplasm. Its non-endemic form typically presents as abdominal mass in children. This rapidly growing tumour may cause symptoms due to mass effect or direct involvement of the bowel. Clinical presentations like acute abdomen can be secondary to intestinal obstruction, intussusception or sometimes perforation.We describe here a case of an adult male with an unusual presentation of appendiceal Burkitt's lymphoma mimicking acute cholecystitis or appendicitis.
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PMID:Primary Burkitt's Lymphoma Of The Appendix Presenting As Acute Abdomen: A Case Report. 2247 Jun 4

Burkitt's lymphoma is a highly aggressive B-lymphoproliferative disorder. Clinically it most often manifests with extranodal involvement, typically affecting the gastrointestinal tract as a large and rapidly proliferating tumor mass, which may present as acute abdomen. We present a case report of a young man admitted with signs of acute appendicitis. A tumor of the ileocaecal junction was discovered perioperatively and resolved by a right-sided hemicolectomy. Histological examination of the tumor confirmed Burkitt's lymphoma. On the ninth postoperative day, the patient developed signs of ileus and a follow-up CT scan showed tumor masses in the area of the ileotransversoanastomosis. He was transferred to undergo radical adjuvant chemotherapy. Intestinal passage was restored during the next two days. Our aim is to report on the limited role of surgical treatment in this type of malignancy, due to the extremely rapid proliferation of the tumor tissue, when the tumor can grow back to its original size over a period of a few hours or days.
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PMID:[Burkitt's lymphoma of the caecum as a rare cause of acute abdomen: a case report]. 2274 88

Malignant tumors of the small bowel presenting as acute abdomen are a rare occurrence. Burkitt's lymphoma presenting as a surgical emergency needing emergency laparotomy is an uncommon presentation of this tumor. We present an interesting case of jejunal perforation as a first manifestation of Burkitt's lymphoma which was successfully managed with surgical resection, high dose chemotherapy, and good supportive care.
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PMID:Jejunal Perforation: A Rare Presentation of Burkitt's Lymphoma-Successful Management. 2499 39

Intussusception is commonly seen in children but is rare in adults and represents only 5% of all intussusceptions causing 1% of intestinal obstructions. More than 50% of these intussusceptions in adults are due to intestinal neoplasms, including malignant lymphoma, e.g., Burkitt lymphoma. These lymphomas are more common in human immunodeficiency virus (HIV)-positive patients than in the general population. We present a case of a young male who was diagnosed with HIV when he developed intestinal obstruction and intussusception secondary to Burkitt lymphoma. He was managed with surgical resection followed by chemotherapy and antiretroviral treatment. HIV patients presenting with acute abdomen pose a diagnostic challenge to clinicians due to a wide range of differential diagnoses including inflammatory, infectious and neoplastic conditions. In a young HIV patient presenting with acute abdomen, intussusception caused by Burkitt lymphoma should be considered in the differential.
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PMID:Burkitt lymphoma as a lead point for jejunojejunal intussusception in a human immunodeficiency virus patient. 2852 28

<strong>BACKGROUND</strong> Appendicitis is the most common cause of an acute abdomen. Approximately 1% of appendicectomies will have an incidental finding of an appendiceal neoplasm. A primary appendiceal lymphoma is extremely rare, and is found in 0.015% of all appendiceal specimens. Burkitt lymphoma is an aggressive B cell lymphoma characterized by translocation and dysregulation of the c-Myc gene. Burkitt leukemia is considered to be an alternative manifestation of the same pathology, and is defined by the presence of >25% Burkitt blasts within the bone marrow. The treatment approaches for Burkitt leukemia/lymphoma are similar. <strong>CASE REPORT</strong> A 6-year old girl presented with a history, examination, and radiological imaging consistent with acute appendicitis. An inflamed, edematous appendix was identified intraoperatively, and a cecectomy was performed. Histopathological investigations demonstrated Burkitt leukemia with isolated extra-nodal involvement of the appendix. The patient was subsequently started on a multi-agent steroid and chemotherapy regimen. A literature review was performed, identifying cases of Burkitt leukemia/lymphoma presenting as appendicitis. <strong>CONCLUSIONS</strong> This case highlights the importance of clinical vigilance and routine specimen histopathology review, and explores key management considerations associated with the incidental diagnosis of Burkitt leukemia/lymphoma.
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PMID:Burkitt Leukemia Presenting as Acute Appendicitis: A Case Report and Literature Review. 3209 18