Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D06522 (Silica)
2,396 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ZC3H4 10.7
L3MBTL2 9.5
CL20 9.5
TICAM1 9.1
Cdc42-interacting protein 4 9.0
GK2 8.8
PHTS 8.6
choline-phosphate cytidylyltransferase 8.6
aminopropyltransferase 8.4
nephronectin 8.3
PSSA 8.1
SIL1 8.1
B-5 7.8
diglyceride kinase 7.8
mpo 7.7
GSTA4 7.7
PHIP 7.7
VAV 7.5
TLL 7.5
macrophage receptor 7.4
macrophage receptor with collagenous structure 7.4
GMD 7.2
CAT-2 7.2
RPL32 7.0
NOX5 6.9
FIZZ1 6.8
TGIF 6.8
Interleukin-17A 6.8
BIII 6.8
HNP 6.8
melastatin 2 6.8
PDEA 6.7
POF 6.7
Zic 6.7
MARCO 6.7
fatty-acid synthase 6.7
Pegasus 6.6
LAMP2 6.6
LSR 6.5
ACN 6.5
NF90 6.5
GSTM3 6.3
MCM 6.3
env protein 6.3
hyodeoxycholic acid 6.2
sarcosine oxidase 6.2
cyclin A1 6.2
SIII 6.1
CEE 6.1
toll-like receptor 9 6.1
SCX 6.0
EOF 6.0
CCL14 6.0
endo-beta-N-acetylglucosaminidase 6.0
PIL 6.0
Tara 6.0
Lnk 6.0
NKX2.5 6.0
SGI 5.9
MSU 5.9
Wilms' tumor suppressor 5.9
L-plastin 5.9
OSC 5.9
GA2 5.8
EDD 5.8
ENV 5.8
DVB 5.8
SA1 5.8
GC2 5.8
NADPH oxidase 1 5.8
RNF8 5.8
UCH-L1 5.8
FER 5.7
UDP-glucose dehydrogenase 5.7
cingulin 5.7
OV-1 5.7
CHN 5.7
arginase II 5.7
protein arginine methyltransferase 5 5.6
HDS 5.6
more...
Disease
Acute silicosis 12.7
Chronic silicosis 11.4
silicosis 9.6
DTGA 8.8
occupational lung disease 8.6
West Nile encephalitis 7.5
pleuropericarditis 7.3
Bed bugs 7.0
dental calculus 6.6
pneumoconiosis 6.5
hypobetalipoproteinemia 6.1
fibroelastosis 6.0
pulmonary fibrosis 5.9
byssinosis 5.9
occupational disease 5.8
EDC 5.7
CHN 5.7
HBD 5.6
HMS 5.5
BEN 5.4
DIA 5.4
asbestosis 5.4
mite infestation 5.4
OCP 5.3
SBS 5.3
SBS 5.3
Vogt 5.2
MAS 5.2
sclerodactyly 5.2
large cell carcinomas 5.2
NF2 5.2
Granuloma 5.2
TEM 5.1
TEM 5.0
RBS 5.0
ash 4.9
EOS 4.9
EOS 4.9
Allergic contact dermatitis 4.8
maple syrup urine disease 4.8
Junin 4.8
Friend leukemia 4.7
sarcoma 180 4.7
PIC 4.7
amebiasis 4.6
CNF 4.6
Condensation 4.6
multicore 4.5
disabling disease 4.5
PMT 4.5
ED2 4.4
KNO 4.4
Kearns-Sayre syndrome 4.4
PAA 4.4
urosepsis 4.3
LCD 4.2
NPS 4.2
scleroderma 4.2
PCS 4.2
tooth wear 4.1
IPS 4.1
adrenal adenoma 4.1
PMS 4.1
SEM 4.1
lipid disorder 4.1
paroxysmal supraventricular tachycardia 4.1
anaplastic thyroid cancer 4.1
lymphosarcoma 4.0
Mastitis 3.9
acute monocytic leukemia 3.9
rind 3.9
PAM 3.9
PSS 3.9
cervical adenocarcinoma 3.8
HCA 3.8
NOD 3.8
CMV retinitis 3.8
lung disease 3.8
urolithiasis 3.7
DMS 3.7
more...
Symptom
Halo 5.8
Spots 4.9
Respiratory symptoms 4.8
acidity 4.1
HSA 3.1
oliguria 2.8
agitation 2.5
collapse 2.4
Wind 2.3
shortness of breath 1.3
thinning 1.2
myalgia 1.0
vertigo 0.9
erythema 0.0
fatigue -0.4
hypothermia -0.4
tremor -0.5
discomfort -0.8
cough -0.8
discomfort -0.9
abdominal pain -1.2
anesthesia -1.5
seizures -2.6
pain -2.7
Drug
Silica 13.7
Ferric oxide 10.7
Tenatoprazole 10.7
Atractylodes rhizome 9.5
Belladonna 8.7
Parsol 8.5
Flunisolide 8.1
Barium sulfate 7.9
SiO2 7.9
Silica gel 7.8
Dextran sulfate sodium 7.7
Velban 7.5
Human Serum Albumin 7.5
Clove 7.0
CA-074 6.9
Span 20 6.7
Rhamnose 6.5
Rebamipide 6.5
Avicel PH 6.3
EPL 6.3
Florisil 6.1
PZC 6.0
Diclofenac sodium 6.0
Talc 6.0
Ethylenediamine 6.0
CEC 5.8
Kaolin 5.8
TFT 5.7
Cellulose acetate 5.6
Gel 5.6
IPD 5.5
Menthol 5.4
Guanidine 5.3
Guanidine 5.3
MEA 4.9
Maltose 4.9
Cibacron Blue 4.8
TiO2 4.8
Fluorescein 4.6
Donepezil 4.6
Indocyanine green 4.6
Helium 4.4
CFS 4.4
Methylene blue 4.4
Ganciclovir 4.1
Fluorescein 4.1
APD 3.9
Photofrin 3.9
Isoniazid 3.8
TAK 3.7
Acyclovir 3.7
Ketoconazole 3.7
Clopidogrel 3.6
Hypaque 3.6
MDS 3.6
ZnO 3.5
RFP 3.5
Hypaque 3.4
Fraction 3.4
CCL 3.4
Pronase 3.4
ZnCl2 3.3
ZnCl2 3.3
NBT 3.3
ROS 3.3
Glycyrrhiza 3.2
Prednisolone 3.2
Sorafenib 3.1
MgSO4 3.1
VCR 3.1
MIL 3.1
Simvastatin 3.0
MRC 3.0
HCH 2.9
Docetaxel 2.9
Parkin 2.8
Parkin 2.8
p75 2.8
CAM 2.8
Leaf 2.8
more...
Enzyme
hydroxylaminobenzene mutase 10.7
CMP-KDO synthetase 8.3
GK2 8.2
endoglycoceramidase 7.4
phosphatidylglycerophosphate synthase 7.0
sucrose phosphorylase 7.0
phosphocholine cytidylyltransferase 7.0
fatty-acid synthase 6.4
ceramidase 6.3
sarcosine oxidase 6.3
lysophosphatidylcholine acyltransferase 5.7
UDP-glucose dehydrogenase 5.4
spermidine synthase 5.3
phosphatidylinositol 4-kinase 5.3
alpha-L-fucosidase 5.2
dextranase 5.1
PMT 5.1
choline kinase 4.9
diacylglycerol kinase 4.8
alpha-L-fucosidase 4.7
alpha-L-fucosidase 4.7
DTA 4.6
NAT 4.3
microsomal epoxide hydrolase 4.1
S-adenosylmethionine decarboxylase 3.9
glucose oxidase 3.9
acylase 3.9
BMA 3.9
delta-aminolevulinic acid dehydratase 3.9
PAM 3.8
lysozyme 3.8
cytidine deaminase 3.8
ACS 3.8
cathepsin L 3.8
BAL 3.7
angiotensin-converting enzyme 2 3.7
cathepsin B 3.7
TPP 3.4
ribonuclease 3.3
ribonuclease 3.3
cathepsin D 3.3
lactate dehydrogenase 3.3
TPP 3.2
sialyltransferase 3.1
sialyltransferase 3.1
sialyltransferase 3.1
caspase-1 3.1
MIP 3.0
aryl hydrocarbon hydroxylase 3.0
papain 3.0
alpha-galactosidase 3.0
hexosaminidase 2.9
prolyl hydroxylase 2.9
endoglycosidase H 2.9
lipase 2.8
arginase 2.8
caspase-9 2.8
paraoxonase 2.7
PAH 2.6
soluble epoxide hydrolase 2.6
glutathione reductase 2.5
thioredoxin reductase 2.4
MAP 2.4
PKG 2.4
thymidine kinase 2.4
peroxiredoxin 2.3
MDP 2.3
firefly luciferase 2.3
protein phosphatase 2A 2.1
phospholipase C 2.1
superoxide dismutase 2.1
5'-nucleotidase 2.1
furin 2.1
aldehyde dehydrogenase 2.0
RNase 2.0
MMP-3 2.0
RNase 1.9
glutathione peroxidase 1.9
catalase 1.8
NADPH oxidase 1.8
more...
Compound
cyclohexanesulfonic acid 13.7
Diphenyldimethoxysilane 13.7
3-methoxyestra-1,3,5(10)-trien-17-one 11.7
1,1,4,4-tetramethyl-2-tetrazene 11.7
1,1,4,4-tetramethyl-2-tetrazene 11.7
4-(2-aminoethyl)phenol 11.5
triethoxy(octyl)silane 11.4
Pinacyanol 11.1
18-Hydroxycortisol 10.7
Trichloroisocyanuric acid 10.7
tetramethyl orthosilicate 10.5
Tectochrysin 10.4
Toremifene citrate 10.4
C4H10O4 10.1
benzyl acrylate 10.0
silicon 9.5
1,2,3-benzenetricarboxylic acid 9.4
tetraethyl orthosilicate 9.2
Glucoraphanin 9.1
dimethyl oxalate 9.1
Vanillyl alcohol 8.8
3-Aminopyridine 8.8
Tetryl 8.7
Kryptofix 2.2 8.7
stearamide 8.6
trimethyl borate 8.5
icosane 8.4
Magnesium hydroxide 8.3
Diol 8.2
ETN 8.1
Flunisolide 8.1
Ethylmorphine 8.1
2-ethylpyridine 8.0
diethyl succinate 8.0
triethoxysilane 8.0
2-methoxy-4-methylphenol 7.9
SiO2 7.8
2,4,6-trichloro-1,3,5-triazine 7.7
APTES 7.7
2-vinylpyridine 7.6
2-vinylpyridine 7.6
2-vinylpyridine 7.6
Rifamycin 7.6
Glabridin 7.5
TLL 7.5
Oxypurinol 7.5
Rifamycin 7.3
tert-butyl acrylate 7.3
methyl palmitate 7.3
Rifamycin 7.3
Pyrethrins 7.2
tetracosane 7.2
Bis-GMA 7.1
GDP-L-fucose 7.1
RUB 7.1
1,8-octanediol 7.1
2,6-dimethylpyridine 7.0
Silver, 7.0
ethyl palmitate 6.9
CeCl3 6.9
2-methylpyridine 6.8
2,5-dihydrofuran 6.8
tetramethylsilane 6.8
dolichyl-phosphate 6.7
Rifamycin 6.6
UDMA 6.6
NH4OH 6.6
Carrageenan 6.5
Dolichol 6.5
ACN 6.5
Erythritol 6.5
C 6 6.5
Span 80 6.4
DOA 6.4
Titanium dioxide 6.3
diphenylphosphine 6.1
triphenylphosphine oxide 6.1
GA2 6.1
9H-fluorene 6.0
tris(2-chloroethyl) phosphate 6.0
more...