Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D06320 (Vorinostat)
 355 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ataxin 3-like 16.5
Josephin domain containing 1 15.5
PEX11B 13.9
ING5 protein 13.6
Histone deacetylase 7 13.1
BRCA1-associated RING domain 1 12.9
CSTP1 12.8
RLN2 12.7
LBH 12.6
VBP1 12.3
USP16 12.1
Protocadherin-1 11.9
MXD1 11.9
Histone deacetylase 11.7
PTENP1 11.5
CALL 11.4
AK7 11.3
PAAF 11.1
REG1 11.0
HDAC11 11.0
HDAC8 10.9
CFLAR 10.9
HDAC6 10.8
C-MET 10.8
HDAC 10.8
Adipose differentiation-related protein 10.6
HDAC9 10.6
Histone H4 10.5
histone deacetylase 10.4
PEX3 10.4
LKR 10.3
ACAM 10.3
D54 10.2
HR23B 10.2
cathepsin L1 10.1
CD112 10.1
alpha tubulin 10.0
NKX6.1 10.0
HDAC7 10.0
HDAC2 9.9
RPA32 9.8
LOR 9.7
HDAC1 9.7
FAS ligand 9.7
GCR 9.7
PMP70 9.6
RTS 9.6
RGS16 9.6
aryl hydrocarbon receptor repressor 9.5
HDAC3 9.4
ITF 9.4
Histone deacetylase 6 9.4
TPI 9.4
RPA70 9.4
AML3 9.3
PRX 9.2
INK4d 9.2
ING1 9.2
ERCC5 9.2
JAK-2 9.1
KLF1 9.0
BMF 9.0
SOX11 8.9
CTCL 8.9
phosphoglycerate kinase 1 8.8
ADO 8.8
OBP 8.8
CIITA 8.7
EPAS1 8.7
HDAC4 8.7
BIK 8.7
HMGIC 8.7
ABCC4 8.6
phospholipase D1 8.6
OSC 8.6
apolipoprotein J 8.6
FFR 8.6
TCF3 8.6
c-FLIP 8.5
L19 8.5
more...
Disease
CMDR 13.5
cutaneous T-cell lymphoma 11.2
Papillary renal cell carcinoma 10.3
pediatric solid tumor 9.6
Fibrosarcoma 9.0
AML/MDS 8.9
RTS 8.9
Sezary syndrome 8.8
pineoblastoma 8.7
adult AML 8.4
CMD 8.3
MDI 8.3
MVA 8.3
CMD 8.3
IPV 8.2
Canavan 8.2
hypermagnesemia 8.1
PBD 8.1
FIP 8.0
PNET 7.8
Vesicular stomatitis 7.7
measurable disease 7.7
ASM 7.7
CHR 7.6
Persistent infection 7.5
Niemann-Pick 7.5
PBT 7.4
Leiomyosarcoma 7.4
cerebellar syndrome 7.4
mycosis fungoides 7.2
ATN 7.0
PNET 7.0
MCL 7.0
mantle cell lymphoma 7.0
AGS 6.9
lipidosis 6.9
APL 6.9
APL 6.8
hematologic malignancies 6.8
Rett syndrome 6.8
Parathyroid 6.7
second cancer 6.6
leukodystrophy 6.6
T-cell lymphoma 6.5
SCH 6.5
NPC 6.4
Neuroblastoma 6.3
Neuroblastoma 6.3
ADH 6.3
PER 6.3
primitive neuroectodermal tumor 6.1
hemoglobinopathies 6.1
APL 6.0
EMD 5.9
Glioblastoma 5.9
TTP 5.9
MICA 5.9
glioblastoma 5.9
torsades de pointes 5.9
primitive neuroectodermal tumor 5.8
erythroderma 5.8
oligodendroglioma 5.7
chordoma 5.7
liposarcoma 5.7
African swine fever 5.6
skin tumor 5.6
solid tumor 5.6
Tumour necrosis 5.5
NHL 5.5
follicular lymphoma 5.5
TAM 5.5
thrombocytopenia 5.5
erythroleukemia 5.5
PML 5.4
TTP 5.4
macroglobulinemia 5.3
tumor growth 5.3
glioblastoma multiforme 5.3
ependymoma 5.3
drug withdrawal 5.3
more...
Symptom
lightheadedness 7.4
decreased appetite 6.3
asthenia 6.1
anorexia 5.7
nausea 5.3
fatigue 4.5
vomiting 4.1
diarrhea 3.8
syncope 3.3
splenomegaly 3.2
dyspnea 1.7
seizures 0.2
pain -1.5
Drug
Lecozotan hydrochloride 16.5
Denibulin hydrochloride 16.5
Disomotide 16.5
Ispinesib mesylate 16.5
Apilimod mesylate 16.5
Esomeprazole sodium 16.5
Vorinostat 16.5
Rebimastat 16.5
Telavancin hydrochloride 16.1
Dronedarone hydrochloride 16.0
Forodesine hydrochloride 15.9
Belotecan hydrochloride 15.9
Pitavastatin calcium 15.5
Iratumumab 15.5
Casopitant mesylate 15.5
Linaclotide acetate 15.5
Enzastaurin hydrochloride 15.5
Atomoxetine hydrochloride 15.5
Disufenton sodium 15.5
Revaprazan hydrochloride 15.5
Tezampanel 15.5
Fenspiride hydrochloride 15.5
Velafermin 15.5
Peginterferon alfa-2b 15.3
Peginterferon alfa-2b 15.3
Sugammadex sodium 15.2
Aliskiren fumarate 15.2
Pemetrexed disodium 15.1
Pazopanib hydrochloride 15.0
Vernakalant hydrochloride 15.0
Farglitazar 14.9
Zosuquidar trihydrochloride 14.9
Duloxetine hydrochloride 14.9
Alosetron hydrochloride 14.9
Eltrombopag olamine 14.9
Denufosol tetrasodium 14.9
Icatibant acetate 14.9
Becatecarin 14.9
Darifenacin hydrobromide 14.7
Apaziquone 14.6
Volociximab 14.6
Canfosfamide hydrochloride 14.5
Lasofoxifene tartrate 14.5
Succinobucol 14.5
Escitalopram oxalate 14.4
Fosamprenavir calcium 14.3
Bavituximab 14.3
Atazanavir sulfate 14.3
Alvocidib 14.2
Bazedoxifene acetate 14.1
Pratosartan 14.1
Conivaptan hydrochloride 14.1
Mapatumumab 14.1
Romidepsin 14.1
Rosuvastatin calcium 14.1
Ziprasidone hydrochloride 14.1
Paclitaxel poliglumex 14.0
Solifenacin succinate 14.0
Tanespimycin 13.9
Pegasys 13.9
Desvenlafaxine succinate 13.9
Lexatumumab 13.9
Soblidotin 13.9
Lumiliximab 13.9
Asoprisnil 13.9
Oncophage 13.9
Lutropin alfa 13.8
Fingolimod hydrochloride 13.8
Dapoxetine hydrochloride 13.8
Insulin glulisine 13.7
Tykerb 13.7
Tandutinib 13.6
Alogliptin benzoate 13.6
Armodafinil 13.6
Mecasermin rinfabate 13.6
Visilizumab 13.6
Talabostat 13.6
Eszopiclone 13.5
Clevudine 13.5
Talaporfin sodium 13.5
more...
Enzyme
aspartoacylase 8.9
serine hydroxymethyltransferase 7.3
TMT 6.8
m-calpain 6.8
arginine deiminase 6.7
delta-aminolevulinic acid dehydratase 6.6
ADH 6.3
GSK 6.3
TSA 6.2
cdc2 5.4
paraoxonase 5.4
chaperonin 5.4
caspase-8 5.3
topoisomerase 5.3
topoisomerase 5.2
CDR 5.2
histone acetyltransferase 5.0
glucokinase 5.0
phosphoinositide 3-kinase 4.9
CPT 4.8
CPT 4.7
proteasome 4.6
cathepsin B 4.4
MDR 4.3
PAH 4.3
PARP 4.3
ACE 4.3
CPT 4.3
alcohol dehydrogenase 4.3
DNA methyltransferase 4.2
deaminase 4.1
demethylase 4.0
MEK 3.9
caspase-3 3.6
ERK 3.6
caspase-9 3.6
thymidine kinase 3.6
guanylate cyclase 3.4
luciferase 3.2
focal adhesion kinase 3.0
mitogen-activated protein kinase 2.9
AMP-activated protein kinase 2.8
lactate dehydrogenase 2.6
ACS 2.5
reverse transcriptase 2.5
collagenase 2.3
catalase 2.3
lipase 2.3
phosphodiesterase 2.3
alanine aminotransferase 1.7
protein kinase 1.1
protein kinase C 0.9
peroxidase 0.5
Compound
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
Triciribine phosphate 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
Triciribine phosphate 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
C14H20N2O3 16.5
4-anilino-4-oxobutanoic acid 15.9
C14H20N2O3 15.5
C14H20N2O3 15.5
C14H20N2O3 15.5
C28H38O5 15.5
C14H20N2O3 14.9
C21H18N2O3 14.9
C18H16N2O2 14.9
C20H24N2O4 14.5
Fungichromin 14.5
Berberine iodide 14.5
Moxifloxacin hydrochloride 14.1
C10H12O4 13.6
Fungichromin 13.5
C14H21N3O2 13.5
heptanamide 13.3
C19H22N2O2 12.6
Imexon 12.5
Talampanel 12.4
L-Alanosine 12.3
Acotiamide 12.2
Emtricitabine 12.2
Temsirolimus 11.9
1-hydrazinophthalazine 11.5
Mometasone furoate 11.4
C12H10O2 11.4
Etoricoxib 11.4
Lopinavir 11.3
5-Azacytidine 11.2
AS-101 11.1
Triacetin 11.1
Aripiprazole 11.0
Biapenem 11.0
Lubiprostone 10.9
Trifluorothymidine 10.9
Clindamycin phosphate 10.8
Eplerenone 10.7
Retigabine 10.5
10-Hydroxycamptothecin 10.4
Perillyl alcohol 10.4
Perillyl alcohol 10.4
Phentermine 10.4
Sertindole 10.4
Amlodipine 10.3
Combretum caffrum 10.2
2-Methoxyestradiol 10.1
Trimetrexate 10.1
5-Aza-2'-deoxycytidine 10.0
Morphine sulfate 9.8
Tigecycline 9.7
SDZ PSC 833 9.6
N-(4-hydroxyphenyl)retinamide 9.5
Telmisartan 9.5
TRU 9.4
Tranylcypromine 9.3
Eicosapentaenoic acid 9.2
more...