KEGG:D06320 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: KEGG:D06320 (Vorinostat)
355 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
histone deacetylase	176
histone	84
Histone deacetylase	67
HDAC	47
Mol	29
Sep	22
HDAC1	21
p53	18
HDAC6	18
p21	17
histone H3	15
insulin	14
HDAC2	11
caspase-3	10
Bcl-2	8
HDAC8	8
proteasome	8
cytokine	7
HDAC3	7
H2AX	7
cyclin D1	6
TNF	6
ERK	6
p27	6
proteasome inhibitor	6
AKT	6
mTOR	6
GSK	6
Erythropoietin	5
ACS	5
BOD	5
AML	5
caspase-8	5
Mcl-1	5
CD4	5
SCH	5
PC-3	5
PI3K	4
RLN2	4
BID	4
epidermal growth factor receptor	4
FLIP	4
AMG	4
BAX	4
RTS	4
c-Myc	4
LBH	4
STAT	4
ACE	4
Ghrelin	4
BET	4
ERK1	4
STAT3	4
Bcl-X	3
Chk1	3
HDAC4	3
SAR	3
JAK2	3
histone H4	3
JNK	3
CIP1	3
Hsp90	3
E-cadherin	3
vascular endothelial growth factor	3
c-FLIP	3
tumor necrosis factor	3
TRAIL	3
HDAC9	3
endoplasmic reticulum	3
mutant p53	3
MMR	3
WAF1	3
hemoglobin	3
AGS	3
NMR	3
TPI	3
NAD	3
PTEN	3
tyrosine kinase	3
Rad51	2

Disease
cancer	169
tumor	87
cutaneous T-cell lymphoma	70
tumor growth	26
breast cancer	20
lymphoma	16
thrombocytopenia	15
HIV	13
glioblastoma	12
acute myeloid leukemia	12
multiple myeloma	11
leukemia	11
hematologic malignancies	10
MCF	10
non-small cell lung cancer	9
carcinogenesis	8
tumorigenesis	7
lung cancer	7
B-cell lymphoma	6
glioma	6
carcinoma	6
malaria	6
SCH	5
neuroblastoma	5
anemia	5
Hodgkin's disease	5
mantle cell lymphoma	5
prostate cancer	5
T-cell lymphoma	5
mycosis fungoides	5
neutropenia	5
colorectal cancer	5
sarcoma	4
Niemann-Pick	4
endometrial cancer	4
depression	4
graft-versus-host disease	4
RTS	4
metastases	4
glioblastoma multiforme	4
solid tumor	4
hepatocellular carcinoma	4
AIDS	4
dehydration	4
diabetes	4
Rett syndrome	4
melanoma	4
tumor progression	3
AGS	3
hypertension	3
myelodysplastic syndrome	3
MDI	3
acute lymphoblastic leukemia	3
SAR	3
mesothelioma	3
epilepsy	3
influenza	3
pancreatic cancer	3
squamous cell carcinoma	3
primary tumor	3
diabetic nephropathy	3
immunodeficiency	3
brain tumor	3
Glioblastoma	2
Huntington's disease	2
pruritus	2
multiple sclerosis	2
aggressiveness	2
lung carcinoma	2
PHA	2
proteinuria	2
follicular lymphoma	2
liposarcoma	2
virus infection	2
cervical cancer	2
renal disease	2
MVA	2
lymphopenia	2
Leukemia	2
measurable disease	2

Drug
Vorinostat	355
lysine	24
Sorafenib	23
Romidepsin	22
Bortezomib	21
Everolimus	17
Bevacizumab	17
Pegasys	16
Cetuximab	15
Ezetimibe	15
Pemetrexed disodium	14
Denosumab	14
Gleevec	14
Sunitinib malate	13
PMPA	13
Rosuvastatin calcium	12
Tenofovir disoproxil fumarate	12
G-CSF	12
Gefitinib	12
Tarceva	11
Lenalidomide	11
CIA	11
Pregabalin	11
Dasatinib	11
Bosentan	10
Peginterferon alfa-2b	10
Aliskiren fumarate	10
Mycophenolic acid	10
Peginterferon alfa-2b	10
Adalimumab	10
Bosentan	10
Duloxetine hydrochloride	10
Pimecrolimus	9
Tocilizumab	9
Darbepoetin alfa	9
Teriparatide	9
Epoetin	9
Exenatide	9
Pitavastatin calcium	8
Entecavir	8
Adefovir dipivoxil	8
Escitalopram oxalate	8
Tykerb	8
Campath	8
Fondaparinux	8
Campath	8
Entecavir	8
Dutasteride	7
Liraglutide	7
IL-1ra	7
Olmesartan medoxomil	7
Vandetanib	7
Raltegravir	7
Etravirine	7
Anakinra	7
Ixabepilone	7
Axitinib	7
Tipifarnib	7
Enfuvirtide	6
Golimumab	6
Fulvestrant	6
Posaconazole	6
Telbivudine	6
Atazanavir sulfate	6
Eszopiclone	6
Abatacept	6
Ciclesonide	6
Valsartan	6
Natalizumab	6
Certolizumab pegol	6
Levitra	6
Clofarabine	6
Darunavir	6
Enzastaurin hydrochloride	5
Zoledronic acid	5
Solifenacin succinate	5
Tapentadol	5
Insulin detemir	5
Deferasirox	5
Zoledronic acid	5

Enzyme
ERK	13
mitogen-activated protein kinase	8
proteasome	8
GSK	6
ACS	5
caspase-3	5
luciferase	4
focal adhesion kinase	4
topoisomerase	4
ACE	4
cdc2	4
topoisomerase	4
catalase	3
MEK	3
caspase-8	3
PARP	3
alcohol dehydrogenase	2
phosphoinositide 3-kinase	2
lactate dehydrogenase	2
reverse transcriptase	2
ADH	2
protein kinase	2
aspartoacylase	1
demethylase	1
collagenase	1
delta-aminolevulinic acid dehydratase	1
CPT	1
protein kinase C	1
chaperonin	1
glucokinase	1
m-calpain	1
serine hydroxymethyltransferase	1
thymidine kinase	1
paraoxonase	1
CPT	1
peroxidase	1
phosphodiesterase	1
alanine aminotransferase	1
PAH	1
DNA methyltransferase	1
TMT	1
CDR	1
AMP-activated protein kinase	1
MDR	1
deaminase	1
guanylate cyclase	1
arginine deiminase	1
TSA	1
CPT	1
histone acetyltransferase	1
cathepsin B	1
lipase	1
caspase-9	1