Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D06320 (Vorinostat)
 355 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
histone deacetylase 176
histone 84
Histone deacetylase 67
HDAC 47
Mol 29
Sep 22
HDAC1 21
p53 18
HDAC6 18
p21 17
histone H3 15
insulin 14
HDAC2 11
caspase-3 10
proteasome 8
HDAC8 8
Bcl-2 8
HDAC3 7
H2AX 7
cytokine 7
more...
Disease
cancer 169
tumor 87
cutaneous T-cell lymphoma 70
tumor growth 26
breast cancer 20
lymphoma 16
thrombocytopenia 15
HIV 13
glioblastoma 12
acute myeloid leukemia 12
leukemia 11
multiple myeloma 11
hematologic malignancies 10
MCF 10
non-small cell lung cancer 9
carcinogenesis 8
tumorigenesis 7
lung cancer 7
glioma 6
B-cell lymphoma 6
more...
Symptom
fatigue 13
nausea 10
diarrhea 9
anorexia 8
vomiting 6
asthenia 2
dyspnea 1
decreased appetite 1
pain 1
syncope 1
seizures 1
lightheadedness 1
splenomegaly 1
Drug
Vorinostat 355
lysine 24
Sorafenib 23
Romidepsin 22
Bortezomib 21
Everolimus 17
Bevacizumab 17
Pegasys 16
Cetuximab 15
Ezetimibe 15
Denosumab 14
Gleevec 14
Pemetrexed disodium 14
PMPA 13
Sunitinib malate 13
Rosuvastatin calcium 12
Tenofovir disoproxil fumarate 12
Gefitinib 12
G-CSF 12
Dasatinib 11
more...
Enzyme
ERK 13
proteasome 8
mitogen-activated protein kinase 8
GSK 6
caspase-3 5
ACS 5
ACE 4
cdc2 4
focal adhesion kinase 4
topoisomerase 4
luciferase 4
topoisomerase 4
MEK 3
catalase 3
caspase-8 3
PARP 3
lactate dehydrogenase 2
phosphoinositide 3-kinase 2
alcohol dehydrogenase 2
protein kinase 2
more...
Compound
DNA 53
Clin 28
lysine 27
Histone 23
sodium 22
Dec 18
MDA 13
salt 13
acetate 13
Aripiprazole 12
bromide 12
oxygen 12
5-Azacytidine 11
Paclitaxel 10
PEG 10
Amlodipine 9
potassium 9
zinc 8
5-Aza-2'-deoxycytidine 7
Rapamycin 7
more...