Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: KEGG:D06320 (Vorinostat)
355 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A new derivative of phenylalanine, phenamide, was discovered from the fermentation broth of an actinomycete identified as a member of the Streptomyces albospinus cluster. Phenamide was purified using successive C18 reverse phase and cation exchange chromatography. Its structure was determined by spectroscopic and chemical methods. Its molecular formula, C14H20N2O3, was determined by HRFAB-MS. Phenamide showed activity against Septoria nodorum, the causal agent of wheat glume blotch.
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PMID:Phenamide, a fungicidal metabolite from Streptomyces albospinus A19301. Taxonomy, fermentation, isolation, physico-chemical and biological properties. 779 37