Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D06103 (
Theophylline
)
2,023
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AMP
205
phosphodiesterase
181
Sep
128
adenosine receptor
86
insulin
63
ATP
57
adenylate cyclase
47
glucagon
31
Mol
24
CO2
24
microsomal
23
adenosine deaminase
22
cyclic nucleotide phosphodiesterase
22
ADP
21
cytochrome P-450
18
renin
17
cyclic AMP phosphodiesterase
16
Gen
16
PDE4
14
COPD
14
mast cell
14
IgE
13
albumin
12
cytochrome P450
12
adenosine A1 receptor
12
vasopressin
12
cytokine
12
somatostatin
11
interferon
11
CYP1A2
11
substance P
10
serum albumin
10
5-hydroxytryptamine
10
prolactin
9
GTP
9
calmodulin
9
PDE
8
Pol
8
alkaline phosphatase
8
erythropoietin
7
adenyl cyclase
7
Mal
7
polypeptide
7
histone deacetylase
7
ATPase
7
calcitonin
7
epididymal
7
IL-8
7
glycoprotein
7
IMP
7
calcium channel
7
ANOVA
7
secretin
7
granulocyte
7
cyclooxygenase
7
hemoglobin
7
cytochrome
6
collagenase
6
serum protein
6
NMR
6
alpha, beta
6
tumor necrosis factor
6
histone
6
REM
6
lipopolysaccharide
6
growth hormone
6
C18
6
adenylyl cyclase
6
Phosphodiesterase
5
GABA
5
GMP
5
NAD
5
CA1
5
RPMI
5
P450
5
PEF
5
olfactory
5
Bcl-2
5
IL-5
5
CYP3A
5
more...
Disease
asthma
275
chronic obstructive pulmonary disease
104
SEM
29
depression
24
cancer
21
fits
19
bronchospasm
18
prematurity
16
congestive heart failure
15
diabetes
15
tumor
15
cholera
15
COPD
14
chronic bronchitis
13
melanoma
12
acute renal failure
11
respiratory disease
10
ischemia
10
renal disease
10
renal failure
10
influenza
9
sympathomimetic
9
heart failure
9
lung disease
9
bronchitis
8
PDE
8
respiratory failure
8
status asthmaticus
8
sleep apnea
8
cold
8
emphysema
8
bronchitis
8
pneumonia
7
uterus
7
hypertension
7
status epilepticus
7
cirrhosis
7
eosinophilia
6
epilepsy
6
gastroesophageal reflux disease
6
obstructive airway disease
6
NAME
6
mole
5
hepatocellular carcinoma
5
stroke
5
childhood asthma
5
neuroblastoma
5
anaphylaxis
5
myocardial ischemia
5
Evans
5
liver disease
5
breast cancer
5
pertussis
5
obstructive sleep apnea
5
cystic fibrosis
5
Thorax
5
obesity
5
Nelson
5
epididymis
5
mole
5
lung cancer
5
MRS
4
SCH
4
encephalopathy
4
chronic renal failure
4
hyperglycemia
4
pulmonary hypertension
4
carcinoma
4
SRS
3
cor pulmonale
3
GSH
3
dehydration
3
sudden infant death syndrome
3
Luminal
3
Merkel cell carcinoma
3
aggression
3
sick sinus syndrome
3
peptic ulcer
3
malnutrition
3
bronchopulmonary dysplasia
3
more...
Symptom
seizures
48
dyspnea
19
tremor
18
cough
12
nausea
12
vomiting
12
diarrhea
12
fatigue
11
headache
11
wheezing
9
agitation
8
hypercapnia
8
anesthesia
8
nausea and vomiting
6
pain
5
hypothermia
5
collapse
4
discomfort
4
incoordination
4
respiratory distress
4
discomfort
4
dizziness
4
weakness
4
CSR
3
hyperoxia
3
spasm
3
sleepiness
3
analgesia
3
insomnia
2
chest pain
2
shortness of breath
2
exertional dyspnea
2
Welt
2
tachypnea
2
chest tightness
2
syncope
2
Periodic breathing
2
localized edema
2
hemiplegia
2
overweight
2
Ill
1
physical appearance
1
flushing
1
functional recovery
1
inanition
1
myalgia
1
decreased appetite
1
asthenia
1
neurological disability
1
exhaustion
1
renal colic
1
twitching
1
pleuritic chest pain
1
thinning
1
ataxia
1
acidity
1
cardialgia
1
sore throat
1
polyuria
1
starvation
1
chronic cough
1
blurred vision
1
erythema
1
Acquired stuttering
1
lethargy
1
ENT
1
regurgitation
1
angina
1
Anoxia
1
tense
1
Drug
Theophylline
2023
caffeine
147
Xanthium
41
Monit
33
Asthma
28
Salbutamol
16
Enprofylline
15
lactose
13
Nephron
13
Ouabain
12
Cimetidine
10
Cimetidine
10
Atropine
9
citric acid
8
Indomethacin
8
Papaverine
7
Cardiovasc
6
Salicylate
5
CTX
5
-deoxyadenosine
5
Histamine
5
Ipratropium bromide
5
CSF
5
Dermatol
5
lysine
5
Glucagon
4
nitroglycerin
4
Prednisolone
4
Rolipram
4
Ethanol
4
Adenosine triphosphate
4
Valproic Acid
3
Gel
3
ICI
3
9-THC
3
Clonidine
3
Adenosine deaminase
3
Amiloride
3
Atrovent
3
Methyldopa
3
Doxofylline
3
Vitamin B
3
Ethylenediamine
3
ampicillin
3
Amiloride
3
Ranitidine
2
Budesonide
2
Forskolin
2
Dial
2
Fenoterol
2
Methylene blue
2
Ringer's solution
2
IL-2
2
CaCl2
2
IFN-gamma
2
MAP
2
Kollidon
2
CaCl2
2
Beta-2
2
Atenolol
2
Riopan
2
Dirithromycin
2
CaCl2
2
Phentolamine
2
NAG
2
Angiotensin II
2
NADH
1
Asn
1
Glide
1
Lactose
1
Roflumilast
1
Kainic acid
1
Gemifloxacin
1
Growth hormone
1
Ethmozine
1
ABC
1
Zileuton
1
Allergen
1
Adriamycin
1
pyridoxal phosphate
1
more...
Enzyme
phosphodiesterase
182
adenylate cyclase
54
PDE
32
adenosine deaminase
22
adenosine deaminase
22
protein kinase
20
renin
17
alkaline phosphatase
8
peroxidase
8
ATPase
7
collagenase
6
mitogen-activated protein kinase
6
guanylate cyclase
5
protein kinase C
5
5'-nucleotidase
4
tyrosinase
4
demethylase
4
ERK
4
adenosine kinase
3
phospholipase C
3
MEK
3
thrombin
3
NO synthase
3
phospholipase A2
3
cGMP phosphodiesterase
3
pyridoxal kinase
3
catalase
3
superoxide dismutase
3
phosphorylase
3
PAH
3
MAT
2
SPT
2
beta-glucuronidase
2
AMPK
2
kallikrein
2
CPT
2
MAT
2
CYP3A4
2
calcineurin
2
trypsin
2
lipoxygenase
2
SPT
2
phosphoinositide 3-kinase
2
glutathione peroxidase
2
MIP
2
ACE
2
lipase
1
deaminase
1
SST
1
prostaglandin synthetase
1
PAF acetyltransferase
1
purine nucleoside phosphorylase
1
MMP
1
PKG
1
phosphofructokinase
1
ornithine decarboxylase
1
histidase
1
nucleotidase
1
PAF acetyltransferase
1
focal adhesion kinase
1
aequorin
1
glutathione reductase
1
monoamine oxidase
1
proteasome
1
sucrase
1
carbonic anhydrase
1
aspartate aminotransferase
1
hexosaminidase
1
phospholipase D
1
nucleotide pyrophosphatase
1
uridine kinase
1
isocitrate dehydrogenase
1
CPT
1
PST
1
tissue kallikrein
1
Mg2+-ATPase
1
elastase
1
lysozyme
1
gamma-glutamyl transpeptidase
1
uricase
1
more...
Compound
Theophylline
2022
Clin
284
AMP
215
cAMP
157
calcium
151
caffeine
147
sodium
146
Dec
124
water
102
glucose
97
Adenosine
89
oxygen
67
ATP
57
cGMP
55
phosphate
49
noradrenaline
46
potassium
43
DNA
34
Aminophylline
30
CO2
29
ADP
28
adenylate
26
Isoproterenol
26
prostaglandin E1
25
acetate
25
Dipyridamole
23
Dipyridamole
23
Dipyridamole
23
Dipyridamole
23
arginine
22
ADP
22
galactose
22
ADP
21
Adrenal
20
ethanol
19
creatinine
18
HCl
18
PEG
17
Insulin
17
Salbutamol
16
glycerol
16
nitric oxide
16
carbonate
15
PGE2
15
leucine
14
bromide
14
Propranolol
14
Propranolol
14
urea
13
salt
13
sodium chloride
13
Ouabain
12
Norepinephrine
12
Dibutyryl cyclic AMP
12
Dibutyryl cyclic AMP
12
Diabetol
11
acetic acid
11
Abbott
11
hydrogen
11
Cardiol
11
methanol
11
Mg2+
10
PEG
10
Verapamil
10
GTP
10
prostacyclin
9
Atropine
9
salicylic acid
9
acetonitrile
9
Theobromine
9
tyrosine
8
Indomethacin
8
5-HT
8
GMP
8
Optimal
8
Verapamil
8
ammonium
8
IMP
7
TSH
7
ethyl acetate
7
more...