Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D06103 (
Theophylline
)
2,023
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AMP
205
phosphodiesterase
181
Sep
128
adenosine receptor
86
insulin
63
ATP
57
adenylate cyclase
47
glucagon
31
Mol
24
CO2
24
microsomal
23
adenosine deaminase
22
cyclic nucleotide phosphodiesterase
22
ADP
21
cytochrome P-450
18
renin
17
Gen
16
cyclic AMP phosphodiesterase
16
mast cell
14
COPD
14
PDE4
14
IgE
13
cytokine
12
adenosine A1 receptor
12
cytochrome P450
12
vasopressin
12
albumin
12
CYP1A2
11
interferon
11
somatostatin
11
substance P
10
5-hydroxytryptamine
10
serum albumin
10
prolactin
9
GTP
9
calmodulin
9
alkaline phosphatase
8
PDE
8
Pol
8
cyclooxygenase
7
more...
Disease
asthma
275
chronic obstructive pulmonary disease
104
SEM
29
depression
24
cancer
21
fits
19
bronchospasm
18
prematurity
16
diabetes
15
cholera
15
tumor
15
congestive heart failure
15
COPD
14
chronic bronchitis
13
melanoma
12
acute renal failure
11
respiratory disease
10
ischemia
10
renal disease
10
renal failure
10
influenza
9
lung disease
9
sympathomimetic
9
heart failure
9
cold
8
PDE
8
status asthmaticus
8
bronchitis
8
respiratory failure
8
sleep apnea
8
emphysema
8
bronchitis
8
hypertension
7
status epilepticus
7
cirrhosis
7
uterus
7
pneumonia
7
epilepsy
6
gastroesophageal reflux disease
6
NAME
6
more...
Symptom
seizures
48
dyspnea
19
tremor
18
nausea
12
vomiting
12
cough
12
diarrhea
12
fatigue
11
headache
11
wheezing
9
agitation
8
anesthesia
8
hypercapnia
8
nausea and vomiting
6
pain
5
hypothermia
5
collapse
4
dizziness
4
discomfort
4
discomfort
4
respiratory distress
4
weakness
4
incoordination
4
sleepiness
3
hyperoxia
3
spasm
3
CSR
3
analgesia
3
syncope
2
localized edema
2
Periodic breathing
2
overweight
2
insomnia
2
chest pain
2
shortness of breath
2
Welt
2
exertional dyspnea
2
chest tightness
2
hemiplegia
2
tachypnea
2
more...
Drug
Theophylline
2023
caffeine
147
Xanthium
41
Monit
33
Asthma
28
Salbutamol
16
Enprofylline
15
lactose
13
Nephron
13
Ouabain
12
Cimetidine
10
Cimetidine
10
Atropine
9
Indomethacin
8
citric acid
8
Papaverine
7
Cardiovasc
6
-deoxyadenosine
5
CSF
5
lysine
5
Salicylate
5
CTX
5
Histamine
5
Dermatol
5
Ipratropium bromide
5
Adenosine triphosphate
4
Glucagon
4
Rolipram
4
nitroglycerin
4
Prednisolone
4
Ethanol
4
Valproic Acid
3
Gel
3
Ethylenediamine
3
Amiloride
3
Doxofylline
3
Atrovent
3
Clonidine
3
Adenosine deaminase
3
ampicillin
3
more...
Enzyme
phosphodiesterase
182
adenylate cyclase
54
PDE
32
adenosine deaminase
22
adenosine deaminase
22
protein kinase
20
renin
17
alkaline phosphatase
8
peroxidase
8
ATPase
7
collagenase
6
mitogen-activated protein kinase
6
protein kinase C
5
guanylate cyclase
5
tyrosinase
4
demethylase
4
5'-nucleotidase
4
ERK
4
catalase
3
PAH
3
cGMP phosphodiesterase
3
phospholipase A2
3
phosphorylase
3
phospholipase C
3
NO synthase
3
thrombin
3
pyridoxal kinase
3
superoxide dismutase
3
adenosine kinase
3
MEK
3
glutathione peroxidase
2
phosphoinositide 3-kinase
2
beta-glucuronidase
2
MIP
2
AMPK
2
MAT
2
SPT
2
SPT
2
trypsin
2
calcineurin
2
more...
Compound
Theophylline
2022
Clin
284
AMP
215
cAMP
157
calcium
151
caffeine
147
sodium
146
Dec
124
water
102
glucose
97
Adenosine
89
oxygen
67
ATP
57
cGMP
55
phosphate
49
noradrenaline
46
potassium
43
DNA
34
Aminophylline
30
CO2
29
ADP
28
Isoproterenol
26
adenylate
26
prostaglandin E1
25
acetate
25
Dipyridamole
23
Dipyridamole
23
Dipyridamole
23
Dipyridamole
23
arginine
22
galactose
22
ADP
22
ADP
21
Adrenal
20
ethanol
19
HCl
18
creatinine
18
Insulin
17
PEG
17
glycerol
16
more...