Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D06103 (Theophylline)
 2,023 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AMP 205
phosphodiesterase 181
Sep 128
adenosine receptor 86
insulin 63
ATP 57
adenylate cyclase 47
glucagon 31
CO2 24
Mol 24
microsomal 23
adenosine deaminase 22
cyclic nucleotide phosphodiesterase 22
ADP 21
cytochrome P-450 18
renin 17
cyclic AMP phosphodiesterase 16
Gen 16
PDE4 14
mast cell 14
more...
Disease
asthma 275
chronic obstructive pulmonary disease 104
SEM 29
depression 24
cancer 21
fits 19
bronchospasm 18
prematurity 16
congestive heart failure 15
tumor 15
cholera 15
diabetes 15
COPD 14
chronic bronchitis 13
melanoma 12
acute renal failure 11
renal failure 10
renal disease 10
respiratory disease 10
ischemia 10
more...
Symptom
seizures 48
dyspnea 19
tremor 18
cough 12
nausea 12
vomiting 12
diarrhea 12
fatigue 11
headache 11
wheezing 9
agitation 8
anesthesia 8
hypercapnia 8
nausea and vomiting 6
hypothermia 5
pain 5
collapse 4
dizziness 4
respiratory distress 4
discomfort 4
more...
Drug
Theophylline 2023
caffeine 147
Xanthium 41
Monit 33
Asthma 28
Salbutamol 16
Enprofylline 15
lactose 13
Nephron 13
Ouabain 12
Cimetidine 10
Cimetidine 10
Atropine 9
citric acid 8
Indomethacin 8
Papaverine 7
Cardiovasc 6
-deoxyadenosine 5
Salicylate 5
Dermatol 5
more...
Enzyme
phosphodiesterase 182
adenylate cyclase 54
PDE 32
adenosine deaminase 22
adenosine deaminase 22
protein kinase 20
renin 17
alkaline phosphatase 8
peroxidase 8
ATPase 7
mitogen-activated protein kinase 6
collagenase 6
protein kinase C 5
guanylate cyclase 5
demethylase 4
5'-nucleotidase 4
tyrosinase 4
ERK 4
phospholipase A2 3
NO synthase 3
more...
Compound
Theophylline 2022
Clin 284
AMP 215
cAMP 157
calcium 151
caffeine 147
sodium 146
Dec 124
water 102
glucose 97
Adenosine 89
oxygen 67
ATP 57
cGMP 55
phosphate 49
noradrenaline 46
potassium 43
DNA 34
Aminophylline 30
CO2 29
more...