Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D05575 (
Pramipexole
)
205
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
tyrosine hydroxylase
11
dopamine D2 receptor
10
Sep
10
dopamine D3 receptor
5
prolactin
5
CGI
5
SCH
5
D3R
5
Mol
5
neurotrophic factor
4
Bcl-2
4
VMAT2
3
Pol
3
olfactory
3
hOCT2
3
DAT
3
dopamine transporter
3
HEK
2
D2R
2
ubiquitin
2
cytochrome
2
dopamine D1 receptor
2
Nurr1
2
DCX
2
MPP
2
superoxide dismutase
2
glutathione peroxidase
2
catalase
2
PPX
2
MES
2
CA1
2
synuclein
2
growth hormone
2
D2 dopamine receptor
2
dopa decarboxylase
2
proteasome
2
brain-derived neurotrophic factor
2
caspase-3
2
microtubule associated protein
2
lactate dehydrogenase
2
more...
Disease
Parkinson's disease
113
restless legs syndrome
28
depression
25
pathological gambling
8
hallucinations
7
dyskinesia
7
parkinsonism
7
major depressive disorder
6
psychosis
6
SCH
5
schizophrenia
5
neuroblastoma
4
akinesia
4
bipolar depression
4
amyotrophic lateral sclerosis
3
mania
3
anhedonia
3
unipolar depression
3
movement disorder
3
addiction
3
delusions
3
Alzheimer's disease
3
hypersexuality
2
mental illness
2
compulsion
2
stroke
2
ICH
2
drug addiction
2
major depressive episode
2
cocaine abuse
2
ischemia
2
cognitive impairment
2
chronic pain
2
catalepsy
2
incontinence
1
subarachnoid hemorrhage
1
behavior disorder
1
macular degeneration
1
hypomania
1
diabetes
1
more...
Symptom
sleepiness
12
tremor
9
insomnia
8
nausea
7
pain
4
dystonia
3
fatigue
3
constipation
2
agitation
2
hypothermia
2
dizziness
2
motor symptom
2
shoulder pain
1
discomfort
1
hypotonia
1
anesthesia
1
dysesthesia
1
muscle rigidity
1
apathy
1
bradykinesia
1
vomiting
1
eds
1
Psychiatric symptoms
1
leg edema
1
discomfort
1
paresthesia
1
Other hallucinations
1
orofacial pain
1
consciousness disturbance
1
Drug
Pramipexole
205
Pramipexole
204
Rotigotine
4
Mirapex
4
Spectrum
2
Sulpiride
2
Prozac
1
ROS
1
Pregabalin
1
DEX
1
Lisuride
1
Tapentadol
1
Carbidopa
1
Portal
1
MAP
1
Cimetidine
1
Azithromycin
1
Rasagiline
1
Frentizole
1
Cimetidine
1
Modafinil
1
Akineton
1
TAK
1
Sinemet
1
Etilevodopa
1
Enzyme
tyrosine hydroxylase
11
DAT
3
superoxide dismutase
3
glutathione peroxidase
2
catalase
2
lactate dehydrogenase
2
caspase-3
2
proteasome
2
MPP
2
protein kinase
1
AMP-activated protein kinase
1
AMPK
1
ACS
1
monoamine oxidase
1
mitogen-activated protein kinase
1
DOPA decarboxylase
1
complex I
1
creatine kinase
1
AMPK
1
MAP
1
phosphodiesterase
1
aconitase
1
PARP
1
luciferase
1
Compound
Clin
16
Dec
15
L-DOPA
13
Dopamine
11
oxygen
9
water
8
sodium
7
Ropinirole
6
MPTP
6
hydrogen
5
salt
4
DAT
3
nitric oxide
3
calcium
3
H2O2
3
DSM
2
MES
2
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
2
5-HT
2
glutamate
2
acetate
2
PD 168
2
MPP
2
Bromocriptine
2
DNA
2
phosphate
2
MTT
2
dUTP
2
tyrosine
2
iron
2
MPP
2
Pergolide
2
MES
2
DOPAC
1
TPA
1
Amantadine
1
Chloroquine
1
TPA
1
ethanol
1
MAP
1
more...