Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D04296 (
Asthma
)
25,733
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
1701
IgE
1136
cytokine
572
IL-5
387
IL-4
342
IL-13
336
Mol
238
FEV
217
mast cell
185
COPD
163
IL-10
153
TNF
146
CD4
144
IFN
127
IL-17
119
IL-6
118
collagen
103
tumor necrosis factor
94
interferon
94
eosinophil cationic protein
92
lymphoid
88
IL-8
79
IFN-gamma
73
IL-33
71
C1 inhibitor
71
eotaxin
70
chemokine
68
gut
64
ICS
61
thymic stromal lymphopoietin
57
interleukin-4
56
PEF
51
She
49
IgA
49
lipopolysaccharide
49
TNF-alpha
48
CD8
46
Pol
46
IL-2
44
Cytokine
42
HLA
42
bradykinin
40
CD25
38
ICD
38
mucin
34
IL-9
34
C-reactive protein
33
Mal
33
TLR4
32
NDF
32
IL-25
31
phosphodiesterase
31
TGF-beta
31
IL-1
30
periostin
30
interferon-gamma
29
GM-CSF
29
p38
28
vascular endothelial growth factor
28
X-linked
28
histone
28
San
28
ADAM33
27
reserved
27
CCR3
27
insulin
26
glucocorticoid receptor
26
cyclooxygenase
25
5-lipoxygenase
25
ICAM-1
24
kit
24
ACT
24
matrix metalloproteinase
23
inducible nitric oxide synthase
23
IL-23
23
RANTES
23
human leukocyte antigen
22
SDS
22
IL-4 receptor
22
PBS
22
more...
Disease
asthma
25733
allergic rhinitis
920
chronic obstructive pulmonary disease
599
rhinitis
598
childhood asthma
444
chronic disease
374
atopic dermatitis
359
respiratory disease
334
eosinophilia
333
anaphylaxis
297
urticaria
261
eczema
245
obesity
241
food allergy
240
lung disease
185
COPD
163
immunodeficiency
148
gastroesophageal reflux disease
143
pruritus
139
depression
135
sinusitis
133
cancer
133
bronchospasm
124
cold
122
hay fever
113
Hereditary angioedema
109
pneumonia
108
diabetes
104
virus infection
94
cystic fibrosis
89
bronchitis
87
infectious diseases
85
influenza
85
rash
84
bronchitis
83
chronic urticaria
82
chronic sinusitis
82
Thoracic
82
otitis media
76
hypertension
76
bronchiolitis
72
polyposis
69
tuberculosis
68
autoimmune disease
67
chronic bronchitis
67
bronchiectasis
65
status asthmaticus
64
ICS
62
multiple sclerosis
61
aspergillosis
59
emphysema
59
conjunctivitis
59
respiratory infection
57
West
55
tumor
53
rheumatoid arthritis
53
allergic conjunctivitis
51
dermatitis
51
vasculitis
49
skin disease
45
drug hypersensitivity
45
Allergic asthma
43
Churg-Strauss syndrome
40
obstructive sleep apnea
39
Contact Dermatitis
38
ICD
38
systemic lupus erythematosus
36
HIV
36
Atopic
36
respiratory failure
35
immunopathology
32
esophagitis
31
hypersensitivity pneumonitis
31
Thorax
30
sickle cell disease
30
sleep disturbances
29
mastocytosis
27
immune deficiency
27
Bronchial hyperresponsiveness
27
arthritis
27
more...
Symptom
wheezing
686
cough
433
dyspnea
345
shortness of breath
116
chest tightness
106
rhinorrhea
91
nasal congestion
87
chronic cough
83
pain
81
sneezing
78
overweight
73
fatigue
61
headache
53
Welt
47
sleepiness
47
respiratory distress
46
diarrhea
43
vomiting
42
discomfort
38
discomfort
34
erythema
30
anesthesia
29
abdominal pain
28
nocturnal cough
28
nausea
24
Respiratory symptoms
22
collapse
22
flushing
20
seizures
19
spasm
17
postnasal drip
17
stridor
16
tremor
16
insomnia
14
chest pain
14
hoarseness
13
arthralgia
13
heartburn
12
persistent cough
12
dizziness
12
productive cough
12
snoring
11
syncope
11
anosmia
11
hemoptysis
10
exertional dyspnea
10
alexithymia
10
weakness
10
itchy nose
9
facial pain
9
ENT
9
dry eye
8
hepatosplenomegaly
8
nasal discharge
8
chills
8
stigma
8
hypercapnia
8
hypocapnia
7
myalgia
7
splenomegaly
7
sore throat
6
Nasal symptoms
6
bitter taste
6
labored breathing
5
Ill
5
angina
5
regurgitation
5
vertigo
4
exhaustion
4
fever of unknown origin
4
Depressive symptoms
4
pallor
4
lethargy
4
rales
4
cyanosis
3
constipation
3
lightheadedness
3
cachexia
3
analgesia
3
agitation
3
more...
Drug
Asthma
25733
Allergen
129
Omalizumab
76
IFN-gamma
73
IL-2
45
Budesonide
36
Histamine
34
Salbutamol
32
CSF
32
Theophylline
28
Leaf
27
ACT
24
ROC
18
Dermatol
16
Mepolizumab
15
Ciclesonide
14
vitamin E
14
Monit
14
Xanthium
12
Loratadine
10
Mometasone furoate
10
lysine
10
ascorbate
9
Android
9
ENT
9
Ipratropium bromide
8
Ranitidine
8
ROS
8
EPA
8
Fluticasone propionate
8
Becotide
8
Alliance
8
MAP
8
Nitric Oxide
8
Glycyrrhiza
7
Prednisone
7
PFT
6
Ventolin
6
ETS
6
Ketotifen
6
MgSO4
5
Check
5
Diurnal
5
MRC
5
Spectrum
5
Olopatadine hydrochloride
5
Fluticasone furoate
5
lactose
5
Foradil
4
Bifidobacterium
4
Prednisolone
4
ICI
4
Foradil
4
MINO
4
IPD
4
Ecallantide
4
Foradil
4
Albumin
4
CAM
4
citric acid
4
Dakar
3
Itraconazole
3
IFN-beta
3
Arial
3
Atrovent
3
Magnesium sulfate
3
Nedocromil sodium
3
Heme
3
Intal
3
nitroglycerin
3
Flunisolide
3
DEX
3
p75
3
PFA
3
BCG vaccine
3
Fragment
3
ABC
3
Flixotide
3
Roflumilast
3
Patanol
3
more...
Enzyme
trypsin
54
mitogen-activated protein kinase
53
tryptase
48
ERK
37
peroxidase
36
phosphodiesterase
31
superoxide dismutase
27
catalase
23
Der p 1
22
BAL
20
plasmin
18
kallikrein
18
focal adhesion kinase
16
luciferase
16
protein kinase
14
ACE
12
arginase
12
calcineurin
12
thrombin
11
collagenase
10
reverse transcriptase
10
chitinase
10
protein kinase C
9
NO synthase
9
APC
9
MIP
9
SPT
8
SPT
8
thyroid peroxidase
8
glutathione peroxidase
7
lipoxygenase
7
neutrophil elastase
7
NADPH oxidase
6
NADPH oxidase
6
pepsin
6
caspase-3
6
glutathione S-transferase
6
aspartate aminotransferase
6
adenosine deaminase
6
adenosine deaminase
6
hexosaminidase
6
MMP
5
GSK
5
PARP
5
MAP
5
IKK
5
hyaluronidase
5
hyaluronidase
5
matrix metalloproteinase 9
4
LTC4 synthase
4
phospholipase A2
4
CYP3A4
4
DNase
4
LTA4 hydrolase
4
caspase-1
4
proteasome
4
guanylate cyclase
4
phosphoinositide 3-kinase
4
aldehyde dehydrogenase
4
adenylate cyclase
4
phospholipase C
3
myosin light chain kinase
3
CFI
3
papain
3
CD10
3
Pla
3
creatine kinase
3
AOR
3
NOS
3
acid phosphatase
3
alanine aminotransferase
3
lactate dehydrogenase
3
elastase
3
transglutaminase
3
matrix metalloproteinase 2
2
beta-lactamase
2
urease
2
PDE
2
TSP-1
2
acetylcholinesterase
2
more...
Compound
Dec
1615
Clin
1605
nitric oxide
303
DNA
220
oxygen
169
TNF
146
sodium
101
water
84
nitrogen
80
vitamin D
76
calcium
67
CO2
60
acetate
57
Pac
54
ASA
47
sulfate
46
phosphate
42
bromide
39
His
38
Vitamin D
37
arginine
37
Salbutamol
35
Histamine
34
Theophylline
33
Optimal
32
6-12
31
Montelukast
29
SDS
29
cAMP
23
glucose
23
CAM
22
Methacholine
22
HFA
22
Adrenal
21
BAL
20
ethanol
20
SO2
19
creatinine
19
ECP
19
Dexamethasone
19
ECP
19
ECP
19
MDR
18
Formoterol
18
GSH
17
CAP
17
CAP
17
Salmeterol
17
galactose
17
GSH
17
potassium
16
AMP
16
aluminum
16
zinc
16
toluene
16
serine
15
MTT
15
nickel
14
Disodium cromoglycate
14
salt
14
cysteine
14
tyrosine
13
hydroxide
13
LTC4
13
INH
13
Pyruvate
13
PGD2
12
formaldehyde
12
MDA
12
formaldehyde
12
ACTH
12
PAS
11
lysine
11
BCG
11
nitrate
11
chlorine
10
Fluticasone
10
Fluticasone
10
Asp
9
Fexofenadine
9
more...