Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D04296 (Asthma)
25,733 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1701
IgE 1136
cytokine 572
IL-5 387
IL-4 342
IL-13 336
Mol 238
FEV 217
mast cell 185
COPD 163
IL-10 153
TNF 146
CD4 144
IFN 127
IL-17 119
IL-6 118
collagen 103
interferon 94
tumor necrosis factor 94
eosinophil cationic protein 92
lymphoid 88
IL-8 79
IFN-gamma 73
C1 inhibitor 71
IL-33 71
eotaxin 70
chemokine 68
gut 64
ICS 61
thymic stromal lymphopoietin 57
interleukin-4 56
PEF 51
lipopolysaccharide 49
IgA 49
She 49
TNF-alpha 48
CD8 46
Pol 46
IL-2 44
Cytokine 42
more...
Disease
asthma 25733
allergic rhinitis 920
chronic obstructive pulmonary disease 599
rhinitis 598
childhood asthma 444
chronic disease 374
atopic dermatitis 359
respiratory disease 334
eosinophilia 333
anaphylaxis 297
urticaria 261
eczema 245
obesity 241
food allergy 240
lung disease 185
COPD 163
immunodeficiency 148
gastroesophageal reflux disease 143
pruritus 139
depression 135
cancer 133
sinusitis 133
bronchospasm 124
cold 122
hay fever 113
Hereditary angioedema 109
pneumonia 108
diabetes 104
virus infection 94
cystic fibrosis 89
bronchitis 87
infectious diseases 85
influenza 85
rash 84
bronchitis 83
chronic sinusitis 82
chronic urticaria 82
Thoracic 82
hypertension 76
otitis media 76
more...
Symptom
wheezing 686
cough 433
dyspnea 345
shortness of breath 116
chest tightness 106
rhinorrhea 91
nasal congestion 87
chronic cough 83
pain 81
sneezing 78
overweight 73
fatigue 61
headache 53
Welt 47
sleepiness 47
respiratory distress 46
diarrhea 43
vomiting 42
discomfort 38
discomfort 34
erythema 30
anesthesia 29
nocturnal cough 28
abdominal pain 28
nausea 24
collapse 22
Respiratory symptoms 22
flushing 20
seizures 19
spasm 17
postnasal drip 17
stridor 16
tremor 16
insomnia 14
chest pain 14
hoarseness 13
arthralgia 13
persistent cough 12
heartburn 12
dizziness 12
more...
Drug
Asthma 25733
Allergen 129
Omalizumab 76
IFN-gamma 73
IL-2 45
Budesonide 36
Histamine 34
Salbutamol 32
CSF 32
Theophylline 28
Leaf 27
ACT 24
ROC 18
Dermatol 16
Mepolizumab 15
Ciclesonide 14
Monit 14
vitamin E 14
Xanthium 12
Loratadine 10
Mometasone furoate 10
lysine 10
ENT 9
ascorbate 9
Android 9
ROS 8
Ipratropium bromide 8
Ranitidine 8
Nitric Oxide 8
EPA 8
Alliance 8
MAP 8
Fluticasone propionate 8
Becotide 8
Prednisone 7
Glycyrrhiza 7
Ketotifen 6
PFT 6
Ventolin 6
ETS 6
more...
Enzyme
trypsin 54
mitogen-activated protein kinase 53
tryptase 48
ERK 37
peroxidase 36
phosphodiesterase 31
superoxide dismutase 27
catalase 23
Der p 1 22
BAL 20
plasmin 18
kallikrein 18
focal adhesion kinase 16
luciferase 16
protein kinase 14
arginase 12
calcineurin 12
ACE 12
thrombin 11
chitinase 10
reverse transcriptase 10
collagenase 10
NO synthase 9
MIP 9
protein kinase C 9
APC 9
thyroid peroxidase 8
SPT 8
SPT 8
lipoxygenase 7
glutathione peroxidase 7
neutrophil elastase 7
NADPH oxidase 6
NADPH oxidase 6
hexosaminidase 6
glutathione S-transferase 6
pepsin 6
caspase-3 6
adenosine deaminase 6
adenosine deaminase 6
more...
Compound
Dec 1615
Clin 1605
nitric oxide 303
DNA 220
oxygen 169
TNF 146
sodium 101
water 84
nitrogen 80
vitamin D 76
calcium 67
CO2 60
acetate 57
Pac 54
ASA 47
sulfate 46
phosphate 42
bromide 39
His 38
Vitamin D 37
arginine 37
Salbutamol 35
Histamine 34
Theophylline 33
Optimal 32
6-12 31
SDS 29
Montelukast 29
glucose 23
cAMP 23
HFA 22
Methacholine 22
CAM 22
Adrenal 21
BAL 20
ethanol 20
SO2 19
ECP 19
Dexamethasone 19
ECP 19
more...