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Query: KEGG:D04296 (Asthma)
 25,733 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Allergic dermatosis is a class of immunologic skin diseases manifested as intense itching, which potentially leads to a cycle of skin pain, damage, and infection. Information collected from clinical samples on health-related quality of life shows that some individuals may suffer from poor-quality sleep, physical and emotional distress, and limitations in social functioning. Although many individual factors may moderate the impact of disease on quality of life, disease severity is consistently linked to amount of limitation. There are only sparse data from population surveys in which participants are not selected based on willingness to join a treatment trial for relief of symptoms. This article presents quality-of-life and disease burden data on 559 persons in a community survey who reported signs and symptoms consistent with allergic dermatosis. Quality of life was assessed using the Dermatology-specific Quality of Life (DSQL) questionnaire. Overall, greater disease severity was associated with higher DSQL scores. Noticeable deficits were reported among those who rated their disease as moderate or severe, especially in terms of physical discomfort, sleep disturbance, and negative self-perceptions and emotions. These complaints correlated significantly with out-of-pocket expenses for lotions and emollients to control skin disease. Despite these complaints, the median number of days from the last primary healthcare visit was 453 days, indicating that many dermatosis sufferers are not accessing expert medical care that could alleviate distress.
Curr Allergy Asthma Rep 2001 Jul
PMID:Effects of allergic dermatosis on health-related quality of life. 1189 52

Background: Atopic dermatitis (AD) is a dermatologic condition that affects a large percentage of children and adults in the United States. The disease process is not fully understood, and, currently, there is no cure, so today's treatment methodologies focus on the rash and the symptoms, e.g., pruritus. Even though there is no mortality with this condition, there is significant morbidity and burden. Objective: This review concentrated on several areas in which AD influences quality of life. The areas include sleep, interference with daily activities (e.g., school and/or work), psychological stressors, and the impact on parents and caregivers. The direct and indirect costs of AD are also examined. Methods: A medical literature search was conducted that focused on quality of life (QOL), health-related quality of life, and costs in patients with AD. Results: AD caused poor QOL as assessed in both generic and specific QOL questionnaires. Skin pain was frequently experienced in this condition, which worsens QOL. A significant effect on sleep was found in multiple studies. A large amount of school and/or work absenteeism and psychological stressors was seen in patients with AD. Multiple burdens of the caregivers and parents of patients with AD were documented. Medical costs were also significantly higher compared with patients without AD. Conclusion: The impact of AD is likely more significant than previously acknowledged. AD results in significant morbidity as seen through generic and specific QOL questionnaires, sleep studies, and other questionnaires that measure psychological effects. Physicians should consider evaluating patients with AD beyond their rash and symptoms to achieve the best care possible.
Allergy Asthma Proc 2018 Nov 01
PMID:The burden of atopic dermatitis. 3040 18