Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: KEGG:D04166 (FeCl3)
 1,389 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The relationship between the structure of monomers with amide groups and their adhesiveness to tooth was investigated. The monomers used were methacrylamide (MA), p-methacryloxybenzamide (p-MBA), and 3,5-dimethacryloxybenzamide (3,5-DMBA). MA was commercially available. p-MBA and 3,5-DMBA were prepared from the reaction of methacryloyl chloride with p-hydroxybenzamide or 3,5-dihydroxybenzamide, respectively, in acetonitrile. The bovine enamel and dentin were etched with 10% citric acid -3% FeCl3 solution. The monomers were dissolved in MMA, and TBB-O was used as a polymerization initiator. The test samples were immersed in 37 degrees C water for 1 day, 1 month, or 3 months. Then the tensile bond strengths were measured. The bond strengths to enamel were almost the same, irrespective of the kinds of monomers after 1 day immersion. Although the bond strengths of MA (1.0%) and 3,5-DMBA (3.0%) decreased after 1 month immersion, those of MA (0.5%) and p-MBA (0.5%) did not decrease after 3 months immersion. There was no relationship between the bond strengths to enamel and the bending strengths of the resins. The bond strengths of 3,5-DMBA (1.0%) and 3,5-DMBA (3.0%) to dentin were about 5-7 MPa. The bond strengths of MA (0.5%) or MA (1.0%) decreased after 3 months or 1 month immersion, respectively. The bond strength of p-MBA (0.5%) did not decrease after 3 months immersion.
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PMID:[Studies on adhesion to tooth substrate. 5. The relationship between the structure of monomers and their adhesiveness]. 248 5

In this study the efficacy of the primer on adhesion of MMA (TBB-O) resin to dentin was investigated. The primer consists of two parts. One is 6% MTYA and 70% HEMA aqueous solution, and the other is 2% glutaraldehyde aqueous solution. As an etching agents, 10% citric acid-3% FeCl3 (10-3), 40% phosphoric acid, 10% citric acid, and 0.5 M EDTA were used. After etching, the two parts of the primer were mixed well and applied on the etched surface. Then MMA (TBB-O) resin or p-MBA/MMA (TBB-O) resin was applied on the treated surface. The tensile bond strengths after storage in 37 degrees C water were measured. It revealed that the primer treatment increased the bond strength despite the kind of etching agents. Though the thickness of the resin reinforced dentin was the same as that of demineralized dentin, it was not proportional to the bond strength. Then the durability of the adhesion to dentin treated with primer was examined by the thermal cycling tests. After 2000 thermocycles between 5 degrees C and 55 degrees C, the decrease in the bond strength was very small.
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PMID:[Studies on adhesion of MMA (TBB-O) resin to dentin. The efficacy of the primer treatment]. 249 Feb 3

Bovine enamels cleaned with citric acid and FeCl3 which had been brushed or ground were joined with PMMA rods with the 4-META/MMA-TBB cement. Their tensile adhesive strength was measured after post-treatments. Stable adhesive strength such as 6.2 MPa was obtained on an enamel which was brushed and washed with an aqueous solution of 10% citric acid-3% FeCl3 for 30 sec. even after a 60 times percolation test between 4 degrees C and 60 degrees C. It is adequate to clinics. The value increased to 16.1 MPa on ground enamel. These results suggest that phosphoric acid etching, essential nowadays, is not necessary for good adhesion to enamel. Monomers with both hydrophobic and hydrophilic groups like 4-META possess affinity with tooth substrates and promote the infiltration of cements into the enamel. The infiltrated monomers polymerized in situ and strong adhesion with the enamel took place. Comparison of the tag length formed in the enamel by cements, MMA-TBB, HNPM/MMA-TBB, Phenyl-P/MMA-TBB and 4-META/MMA-TBB supports this consideration.
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PMID:[Studies on dental self-curing resins (22) - adhesion of 4-META/MMA-TBB resin to enamel (author's transl)]. 704 69

The quantitative microleakage of class V cementum (dentin) cavities restored with six dentinal bonding restorative systems was determined in vitro. Ninety extracted human permanent first and second mandibular and maxillary premolars were used in this study. Class V preparations were made in cementum (dentin) at the root facial surfaces. The preparations were restored with 1) a dentin bonding system containing 2% HEMA and BisGMA and a light-cured microfilled composite; 2) the same materials only substituting META/MMA base and TBB catalyst monomers for the BisGMA sealer; 3) a dentin bonding system containing 35% HEMA with META/MMA base and TBB catalyst, and a light-cured hybrid composite; 5) the same dentin bonding system only substituting the 35% glycerylmethacrylate for the 35% HEMA and using the microfilled composite; and 6) the previously described system with a substitution of 0.5 mol EDTA for the 10% citric acid -3% FeCl3. Fifteen teeth were restored with each procedure. The restorations were finished with 12-bladed carbide burs 15 min after placement, the teeth were stored in saline at 37 degrees C for 24 h, finished with Sof-Lex discs and then thermocycled in 2% methylene blue solution 500 times between 50 degrees C and 8 degrees C with a dwell time of 15 s. Quantitative microleakage was determined by a spectrophotometric dye-recovery method and expressed in microgram/dye/restoration. The data were analyzed by ANOVA, Student-Newman-Keuls and Kruskal-Wallis tests. The quantitative microleakage of the teeth restored with the adhesive systems containing 35% glyceryl methacrylate was significantly reduced. The bonding mechanism of glyceryl methacrylate is not known.
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PMID:Quantitative microleakage of some dentinal bonding restorative systems. 859 39

The effectiveness of a barbituric acid/copper (II) chloride initiator system in dentin was examined in terms of the effects of barbituric acid structures and dentin conditioners on bond strength. Curing times and tensile bond strengths to bovine dentin were measured for PMMA/MMA resins in conjunction with initiators consisting of a combination of CuCl2 and four barbituric acids having different substituents. The dentin surfaces were treated with six conditioners consisting of 10% citric acid or phosphoric acid with or without 3% FeCl3 and CuCl2. Among the four barbituric acid systems studied, curing times varied significantly (p < 0.002), but the bond strengths to dentin, conditioned with 10% citric acid containing 3% CuCl2, did not (p > 0.60). The dentin conditioners influenced bond strength significantly (p < 0.02). The phosphoric acid based conditioners produced higher bond strengths than those based on citric acid. The bond strengths obtained under optimal conditions were comparable to those reported for MMA-TBB resin. Thus, the resin applied using the barbituric acid/CuCl2 system worked as well as one of the most effective bonding resins available.
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PMID:Effects of a barbituric acid/CuCl2 initiator system on resin adhesion to dentin. 894 May 60

As a part of a series of studies to examine the role of the initiator system in dentin bonding, the effectiveness of a new polymerization initiator system consisting of 2-methyl-1,3-cyclohexanedione (MCHD) and CuCl2 in dentin bonding was investigated in terms of the effects of dentin conditioners and CuCl2 concentration formulated in MMA/PMMA resins. Curing time and tensile bond strength to bovine dentin were measured using resins composed of MMA containing 0.001-0.03 wt% CuCl2 and PMMA powder containing 2 wt% MCHD. The dentin surfaces were treated with six conditioners consisting of 10 wt% phosphoric acid or citric acid containing 0-3 wt% FeCl3 or CuCl2. The bond strengths of about 10 MPa obtained under optimal conditions were comparable to those reported for tributylborane-initiated MMA resin which is one of the most effective bonding resins available. Thus, the resin using MCHD/CuCl2 system was concluded to be very effective for dentin bonding, especially when dentin was treated with acidic conditioners containing ferric or copper chloride.
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PMID:New initiator system for bonding to dentin using methylcyclohexanedione. 954 99