Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D03899 (
ADR
)
2,057
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ADR
2057
P-glycoprotein
390
Sep
152
P-gp
112
Mol
91
ATP
72
MDR1
70
Bcl-2
53
PEG
51
mdr1
45
p53
40
GSH
40
ATPase
39
caspase-3
38
MRP
35
NMR
35
multidrug resistance-associated protein
35
ACS
34
MRP1
30
MTX
29
more...
Disease
cancer
801
MCF
571
tumor
514
breast cancer
340
leukemia
185
carcinoma
93
tumor growth
90
adenocarcinoma
47
ovarian cancer
45
gastric cancer
41
GSH
40
melanoma
35
CEM
31
metastases
30
hepatocellular carcinoma
29
lung cancer
27
lung carcinoma
27
acute myeloid leukemia
23
epithelial ovarian cancer
22
proteinuria
21
more...
Symptom
vomiting
19
nausea
17
pain
17
dizziness
9
dyspnea
9
diarrhea
8
headache
8
abdominal pain
7
fatigue
5
chest pain
3
chills
3
flushing
3
discomfort
2
heartburn
2
collapse
2
chest tightness
2
discomfort
2
numbness
2
analgesia
2
acidity
2
more...
Drug
ADR
2057
Adriamycin
136
VCR
75
VCR
75
Taxol
23
CTX
22
Dexrazoxane
19
ADM
17
ROS
16
BLM
13
CPM
12
CTX
12
CTX
12
ABC
10
lysine
9
Lipiodol
6
Monit
6
IL-2
6
vitamin E
5
Dial
4
more...
Enzyme
P-glycoprotein
390
MDR
78
mitogen-activated protein kinase
49
topoisomerase
39
ATPase
39
protein kinase C
35
topoisomerase
34
ACS
34
ERK
32
caspase-3
27
protein kinase
26
luciferase
19
caspase-9
16
PARP
14
CYP3A4
14
CPM
12
glutathione S-transferase
11
catalase
11
lactate dehydrogenase
10
caspase-8
10
more...
Compound
ADR
2057
Adriamycin
181
DNA
173
Dec
118
PEG
115
MTT
86
PEG
81
oxygen
80
MDR
78
MDA
75
Clin
73
ATP
72
MMC
47
5-FU
46
GSH
42
GSH
42
iron
40
water
40
calcium
40
sodium
39
more...