Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: KEGG:D03374 (Capsicum)
 2,272 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Oral cancer is linked with apoptotic proteins such as Bcl-xl, Bcl-2 and Mcl-1. Therefore it is of interest to document the molecular docking analysis of capsaicin (principle present in the Capsicum annum) with apoptotic proteins in this context. We report the molecular binding features of capsaicin with apoptotic proteins such as Bcl-xl, Bcl-2 and Mcl-1 for further consideration.
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PMID:Molecular docking analysis of capsaicin with apoptotic proteins. 3299 81

Chili pepper is a prominent cultivated horticultural crop that is traditionally used for food seasoning and is applied for the treatment and prevention of multiple diseases. Its beneficial health properties are due to its abundance and variety of bioactive components, such as carotenoids, capsaicinoids, and vitamins. In particular, carotenoids have important nutraceutical properties, and several studies have focused on their potential in the prevention and treatment of human diseases. In this article, we reviewed the state of knowledge of general aspects of chili pepper carotenoids (biosynthesis pathway, types and content in Capsicum spp., and the effects of processing on carotenoid content) and recent findings on the effects of carotenoid nutraceuticals, such as antioxidant, cancer preventive, anti-inflammatory, cardiovascular disorder preventive, and anti-obesity effects.
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PMID:Chili Pepper Carotenoids: Nutraceutical Properties and Mechanisms of Action. 3326 Sep 97


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