Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D03343 (
MDS
)
2,225
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MDS
2225
AML
585
CML
123
Sep
117
MPN
113
ALL
109
FAB
92
HLA
84
p53
81
erythroid
80
CD34
53
FISH
48
Mol
46
lymphoid
44
hemoglobin
44
TET2
43
RARS
39
JAK2
38
ASXL1
38
cytokine
36
RUNX1
35
NHL
34
SF3B1
33
G-CSF
32
erythropoietin
29
MLL
26
CLL
25
GM-CSF
25
granulocyte colony-stimulating factor
25
ferritin
25
PCA
24
FLT3
24
AML1
23
non-Hodgkin's lymphoma
22
granulocyte
22
She
21
DNMT3A
21
MPD
20
NRAS
20
p15
20
cryptic
19
SCT
19
STR
18
megakaryocyte
17
p13
16
CSF
15
tyrosine kinase
15
NPM1
15
LDH
14
API
14
CD33
14
CD13
14
EPO
14
telomeric
13
DAC
13
ras
12
SAA
12
ara
12
RAI
12
CD4
12
WT1
12
KRAS
12
myeloperoxidase
12
interferon
11
IFN
11
EZH2
11
histone
11
kit
11
GATA2
11
MPL
10
histone deacetylase
10
thrombopoietin
10
DNA methyltransferase
9
CR1
9
CD8
9
CBL
9
Pol
9
HLA-DR
9
CHOP
9
p11
9
more...
Disease
MDS
2225
myelodysplastic syndrome
2225
acute myeloid leukemia
790
cancer
367
leukemia
346
chronic myeloid leukemia
157
Parkinson's disease
155
lymphoma
139
acute lymphoblastic leukemia
133
anemia
126
chronic myelomonocytic leukemia
125
RAEB
124
tumor
117
acute leukemia
103
Leukemia
100
graft-versus-host disease
96
myeloproliferative disorders
88
refractory anemia
87
aplastic anemia
77
movement disorder
68
thrombocytopenia
66
dysplasia
66
multiple myeloma
58
neutropenia
56
non-Hodgkin's lymphoma
54
Hodgkin's disease
50
hematologic malignancies
50
pancytopenia
48
RARS
47
chronic lymphocytic leukemia
39
leukemogenesis
36
chronic lymphocytic leukemia
35
thrombocytosis
35
secondary AML
35
NHL
34
depression
34
AML/MDS
32
juvenile myelomonocytic leukemia
31
iron overload
31
breast cancer
31
myelofibrosis
30
acute nonlymphocytic leukemia
29
trisomy 8
25
RAEB-T
25
myeloid leukemia
24
PCA
24
acute promyelocytic leukemia
23
blast crisis
21
refractory cytopenia with multilineage dysplasia
20
atypical chronic myeloid leukemia
19
SCT
19
cognitive impairment
18
Best
18
essential thrombocythemia
18
Fanconi
18
minimal residual disease
18
pneumonia
17
Therapy-related myelodysplastic syndrome
17
polycythemia vera
17
primary myelofibrosis
16
paroxysmal nocturnal hemoglobinuria
16
dementia
16
MAR
15
WT1
14
immunodeficiency
13
dyskinesia
13
sepsis
13
sepsis
12
Acute graft-versus-host disease
12
trisomy
12
RAEB-2
12
leukopenia
12
carcinoma
11
chronic myeloproliferative disorders
11
myelosuppression
11
Down syndrome
11
primary tumor
11
severe congenital neutropenia
11
diabetes
10
RAEB-1
10
more...
Symptom
tremor
21
fatigue
19
splenomegaly
17
bradykinesia
16
diarrhea
14
motor symptom
10
nausea
8
pain
8
sleepiness
7
hepatosplenomegaly
7
discomfort
7
apathy
6
constipation
6
vomiting
6
weakness
6
hypotonia
5
abdominal pain
4
dystonia
4
seizures
3
myoclonus
3
back pain
3
anorexia
3
dyspnea
3
headache
3
dysarthria
2
bone pain
2
discomfort
2
overweight
2
hypoproteinemia
2
arthralgia
2
hepatomegaly
2
functional recovery
1
Sedation
1
acute abdomen
1
hypothermia
1
chest pain
1
tinnitus
1
agitation
1
right upper quadrant pain
1
angina
1
exertional dyspnea
1
night sweats
1
torticollis
1
ophthalmoplegia
1
cough
1
HSA
1
abnormal gait
1
alexithymia
1
hoarseness
1
dizziness
1
drooling
1
eds
1
limb pain
1
erythema
1
vertigo
1
memory loss
1
pallor
1
cachexia
1
tense
1
Rest tremor
1
Ill
1
spasticity
1
bradypnea
1
consciousness disturbance
1
hemiplegia
1
forgetfulness
1
Stepping
1
fever of unknown origin
1
Drug
MDS
2225
CSF
37
G-CSF
31
Lenalidomide
18
TRM
8
Fludarabine
8
CTX
7
AraC
7
TEL
6
Spectrum
5
DBS
5
IL-2
5
Deferasirox
5
TMS
5
lysine
5
ROS
5
ROC
5
Leaf
4
Revlimid
3
ARA-C
3
Monit
3
Azacytidine
3
TTC
3
MRC
3
Dacogen
2
Posture
2
Dermatol
2
BLM
2
niacin
2
LCM
2
Silica
2
VCR
2
Rituximab
2
Glutathione
2
Epoetin
2
anti-CD33
2
Frontal
2
Vitamin K2
2
Camp
2
LCM
2
Amifostine
2
vitamin E
2
Rasagiline
2
Infliximab
1
THF
1
CPR
1
Infliximab
1
Clofarabine
1
CCL
1
CTX
1
IL-11
1
ADR
1
Istradefylline
1
Gel
1
Exelon
1
MDM
1
IPD
1
ascorbate
1
Alliance
1
Asn
1
Herceptin
1
Ranimustine
1
G418
1
ABC
1
Bayer
1
Sobuzoxane
1
Android
1
IFN-gamma
1
CPT-11
1
Posaconazole
1
Bexxar
1
Everolimus
1
PFA
1
Exelon
1
Lipiodol
1
Spectrum
1
Campath
1
Triad
1
Campath
1
Darbepoetin alfa
1
more...
Enzyme
focal adhesion kinase
51
ERK
49
topoisomerase
40
topoisomerase
40
BMT
39
STR
18
peroxidase
16
CD13
14
DNA methyltransferase
9
mitogen-activated protein kinase
9
lactate dehydrogenase
6
MDR
6
transcriptase
5
reverse transcriptase
5
MEK
5
P-glycoprotein
5
alkaline phosphatase
5
RNA polymerase
5
caspase-3
4
thymidine kinase
4
protein kinase C
4
neutrophil elastase
3
endonuclease
3
tryptase
3
deoxyguanosine kinase
3
AMPK
3
proteasome
3
APC
3
CD10
3
protein kinase
3
ribonucleotide reductase
3
NQO1
3
ribonucleotide reductase
3
AMP-activated protein kinase
3
AMPK
3
alanine aminotransferase
3
thyroid peroxidase
3
NOS
3
PARP
3
DAT
2
calcineurin
2
ACE
2
cytidine deaminase
2
GSK
2
CYP3A4
2
glutathione S-transferase
2
PFI
2
aspartate aminotransferase
2
MPP
2
trypsin
2
isocitrate dehydrogenase
2
isocitrate dehydrogenase
2
CAD
1
PTA
1
phosphoglycerate kinase
1
CPR
1
AST
1
granzyme B
1
CDR
1
purine nucleoside phosphorylase
1
thromboplastin
1
methionine synthase
1
ALA synthase
1
phospholipase C
1
phospholipase D
1
matrix metalloproteinase 2
1
Omi/HtrA2
1
beta-glucuronidase
1
ornithine decarboxylase
1
NADPH oxidase
1
tyrosine hydroxylase
1
asparaginase
1
trypanothione reductase
1
LPL
1
HSD
1
thymidylate synthase
1
NADPH oxidase
1
cdc2
1
PGM
1
deoxycytidine kinase
1
more...
Compound
DNA
176
Dec
152
Clin
108
iron
50
water
47
Ara-C
27
Ara-C
24
5-Azacytidine
22
PDQ
19
TBI
19
retinoic acid
18
acetonitrile
14
ammonium
13
DAC
13
oxygen
12
acetate
11
benzene
11
His
11
hydrogen
10
sodium
10
DFS
10
5-Aza-2'-deoxycytidine
9
BCR
9
MTT
9
formic acid
8
formic acid
8
formic acid
8
formic acid
8
formic acid
8
formic acid
8
formic acid
8
TNF
8
formic acid
8
formic acid
8
formic acid
8
nitrogen
7
CTX
7
methanol
7
bromide
6
MDA
6
zinc
6
CES
6
PEG
6
MDR
6
TEL
6
PEG
5
L-DOPA
5
Pac
5
PAC
5
calcium
5
DBS
5
ITP
5
MTX
5
MEK
5
lysine
5
VP-16
5
Cyclosporine
5
phosphate
5
Methotrexate
5
iodine
4
salt
4
ABL
4
PMA
4
DHB
4
boron
4
phosphorus
4
ethanol
4
glutamine
4
Off
4
potassium
4
Benzene
4
Neo
4
glutamate
4
pyrimidine
3
L-PAM
3
PAS
3
Valproic acid
3
ATP
3
pyrimidine
3
NH2
3
more...