Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D03343 (
MDS
)
2,225
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MDS
2225
AML
585
CML
123
Sep
117
MPN
113
ALL
109
FAB
92
HLA
84
p53
81
erythroid
80
CD34
53
FISH
48
Mol
46
hemoglobin
44
lymphoid
44
TET2
43
RARS
39
JAK2
38
ASXL1
38
cytokine
36
RUNX1
35
NHL
34
SF3B1
33
G-CSF
32
erythropoietin
29
MLL
26
GM-CSF
25
ferritin
25
granulocyte colony-stimulating factor
25
CLL
25
PCA
24
FLT3
24
AML1
23
non-Hodgkin's lymphoma
22
granulocyte
22
DNMT3A
21
She
21
NRAS
20
p15
20
MPD
20
more...
Disease
MDS
2225
myelodysplastic syndrome
2225
acute myeloid leukemia
790
cancer
367
leukemia
346
chronic myeloid leukemia
157
Parkinson's disease
155
lymphoma
139
acute lymphoblastic leukemia
133
anemia
126
chronic myelomonocytic leukemia
125
RAEB
124
tumor
117
acute leukemia
103
Leukemia
100
graft-versus-host disease
96
myeloproliferative disorders
88
refractory anemia
87
aplastic anemia
77
movement disorder
68
thrombocytopenia
66
dysplasia
66
multiple myeloma
58
neutropenia
56
non-Hodgkin's lymphoma
54
Hodgkin's disease
50
hematologic malignancies
50
pancytopenia
48
RARS
47
chronic lymphocytic leukemia
39
leukemogenesis
36
secondary AML
35
chronic lymphocytic leukemia
35
thrombocytosis
35
depression
34
NHL
34
AML/MDS
32
breast cancer
31
iron overload
31
juvenile myelomonocytic leukemia
31
more...
Symptom
tremor
21
fatigue
19
splenomegaly
17
bradykinesia
16
diarrhea
14
motor symptom
10
pain
8
nausea
8
hepatosplenomegaly
7
sleepiness
7
discomfort
7
apathy
6
vomiting
6
weakness
6
constipation
6
hypotonia
5
dystonia
4
abdominal pain
4
myoclonus
3
seizures
3
back pain
3
anorexia
3
dyspnea
3
headache
3
hypoproteinemia
2
overweight
2
dysarthria
2
bone pain
2
discomfort
2
arthralgia
2
hepatomegaly
2
spasticity
1
hypothermia
1
chest pain
1
tinnitus
1
agitation
1
right upper quadrant pain
1
angina
1
exertional dyspnea
1
night sweats
1
more...
Drug
MDS
2225
CSF
37
G-CSF
31
Lenalidomide
18
Fludarabine
8
TRM
8
AraC
7
CTX
7
TEL
6
Spectrum
5
Deferasirox
5
lysine
5
DBS
5
ROC
5
ROS
5
TMS
5
IL-2
5
Leaf
4
MRC
3
TTC
3
Azacytidine
3
Monit
3
ARA-C
3
Revlimid
3
Vitamin K2
2
vitamin E
2
LCM
2
Posture
2
Epoetin
2
Dacogen
2
Dermatol
2
Amifostine
2
Rituximab
2
Silica
2
Frontal
2
Glutathione
2
niacin
2
BLM
2
LCM
2
VCR
2
more...
Enzyme
focal adhesion kinase
51
ERK
49
topoisomerase
40
topoisomerase
40
BMT
39
STR
18
peroxidase
16
CD13
14
DNA methyltransferase
9
mitogen-activated protein kinase
9
MDR
6
lactate dehydrogenase
6
transcriptase
5
P-glycoprotein
5
alkaline phosphatase
5
RNA polymerase
5
reverse transcriptase
5
MEK
5
caspase-3
4
thymidine kinase
4
protein kinase C
4
endonuclease
3
alanine aminotransferase
3
tryptase
3
PARP
3
NQO1
3
protein kinase
3
CD10
3
deoxyguanosine kinase
3
proteasome
3
neutrophil elastase
3
AMP-activated protein kinase
3
APC
3
ribonucleotide reductase
3
ribonucleotide reductase
3
thyroid peroxidase
3
AMPK
3
NOS
3
AMPK
3
calcineurin
2
more...
Compound
DNA
176
Dec
152
Clin
108
iron
50
water
47
Ara-C
27
Ara-C
24
5-Azacytidine
22
PDQ
19
TBI
19
retinoic acid
18
acetonitrile
14
ammonium
13
DAC
13
oxygen
12
benzene
11
acetate
11
His
11
sodium
10
DFS
10
hydrogen
10
MTT
9
BCR
9
5-Aza-2'-deoxycytidine
9
formic acid
8
formic acid
8
formic acid
8
TNF
8
formic acid
8
formic acid
8
formic acid
8
formic acid
8
formic acid
8
formic acid
8
formic acid
8
nitrogen
7
CTX
7
methanol
7
zinc
6
CES
6
more...