Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D03343 (MDS)
 2,225 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MDS 2225
AML 585
CML 123
Sep 117
MPN 113
ALL 109
FAB 92
HLA 84
p53 81
erythroid 80
CD34 53
FISH 48
Mol 46
lymphoid 44
hemoglobin 44
TET2 43
RARS 39
ASXL1 38
JAK2 38
cytokine 36
RUNX1 35
NHL 34
SF3B1 33
G-CSF 32
erythropoietin 29
MLL 26
ferritin 25
granulocyte colony-stimulating factor 25
GM-CSF 25
CLL 25
FLT3 24
PCA 24
AML1 23
non-Hodgkin's lymphoma 22
granulocyte 22
She 21
DNMT3A 21
MPD 20
p15 20
NRAS 20
SCT 19
cryptic 19
STR 18
megakaryocyte 17
p13 16
NPM1 15
CSF 15
tyrosine kinase 15
API 14
CD13 14
EPO 14
CD33 14
LDH 14
DAC 13
telomeric 13
CD4 12
RAI 12
ara 12
SAA 12
WT1 12
myeloperoxidase 12
ras 12
KRAS 12
histone 11
IFN 11
EZH2 11
GATA2 11
kit 11
interferon 11
histone deacetylase 10
thrombopoietin 10
MPL 10
EVI1 9
CBL 9
c-fms 9
p11 9
all-trans 9
HLA-DR 9
myelo 9
NMR 9
TEL 9
CHOP 9
DNA methyltransferase 9
BCR 9
CD8 9
CR1 9
Pol 9
collagen 9
Calreticulin 8
TNF 8
transferrin receptor 8
c-kit 8
SEB 8
TNF-alpha 8
MDS1 8
IL-3 8
olfactory 8
IDH1 8
bcl-2 7
ETO 7
MPV17 7
KIT 7
PTPN11 7
CD38 7
neurofibromatosis 7
Nei 7
PML 7
p10 7
transcobalamin II 7
MRI 7
BCR-ABL1 7
CD117 7
NUP98 7
IDH2 6
esterase 6
STAT5 6
follistatin 6
DIC 6
BRAF 6
p12 6
NF1 6
lactate dehydrogenase 6
HLA-A 6
KMT2A 6
fused 6
caspase-3 6
EFS 6
p21 6
c-myc 6
TK2 6
DGUOK 6
APL 6
NRM 5
C18 5
annexin V 5
REM 5
RARA 5
RIC 5
MTX 5
CD11b 5
CD19 5
granulocyte-macrophage 5
MEC 5
interferon alpha 5
TMS 5
Aiolos 5
PEG 5
ESI 5
G-CSF receptor 5
IL-2 5
P-glycoprotein 5
N-ras 5
DBS 5
ABL1 5
peroxidase 5
TOP1 5
CD14 5
HSC 5
ROS 5
STN 5
more...
Disease
MDS 2225
myelodysplastic syndrome 2225
acute myeloid leukemia 790
cancer 367
leukemia 346
chronic myeloid leukemia 157
Parkinson's disease 155
lymphoma 139
acute lymphoblastic leukemia 133
anemia 126
chronic myelomonocytic leukemia 125
RAEB 124
tumor 117
acute leukemia 103
Leukemia 100
graft-versus-host disease 96
myeloproliferative disorders 88
refractory anemia 87
aplastic anemia 77
movement disorder 68
thrombocytopenia 66
dysplasia 66
multiple myeloma 58
neutropenia 56
non-Hodgkin's lymphoma 54
Hodgkin's disease 50
hematologic malignancies 50
pancytopenia 48
RARS 47
chronic lymphocytic leukemia 39
leukemogenesis 36
secondary AML 35
thrombocytosis 35
chronic lymphocytic leukemia 35
depression 34
NHL 34
AML/MDS 32
juvenile myelomonocytic leukemia 31
breast cancer 31
iron overload 31
myelofibrosis 30
acute nonlymphocytic leukemia 29
trisomy 8 25
RAEB-T 25
PCA 24
myeloid leukemia 24
acute promyelocytic leukemia 23
blast crisis 21
refractory cytopenia with multilineage dysplasia 20
SCT 19
atypical chronic myeloid leukemia 19
cognitive impairment 18
Best 18
minimal residual disease 18
Fanconi 18
essential thrombocythemia 18
pneumonia 17
polycythemia vera 17
Therapy-related myelodysplastic syndrome 17
paroxysmal nocturnal hemoglobinuria 16
primary myelofibrosis 16
dementia 16
MAR 15
WT1 14
dyskinesia 13
immunodeficiency 13
sepsis 13
Acute graft-versus-host disease 12
trisomy 12
sepsis 12
RAEB-2 12
leukopenia 12
carcinoma 11
myelosuppression 11
severe congenital neutropenia 11
chronic myeloproliferative disorders 11
Down syndrome 11
primary tumor 11
West 10
tumorigenesis 10
RAEB-1 10
sarcoma 10
diabetes 10
erythroleukemia 9
megaloblastic anemia 9
influenza 9
macroglobulinemia 9
follicular lymphoma 9
parkinsonism 9
eosinophilia 9
ovarian cancer 9
cytomegalovirus 9
macrocytic anemia 8
veno-occlusive disease 8
residual disease 8
Alzheimer's disease 8
Syndrome 8
fungal infection 8
SDS 8
idiopathic thrombocytopenic purpura 8
PML 8
agranulocytosis 8
lissencephaly 7
hairy cell leukemia 7
lymphoblastic leukemia 7
lymphadenopathy 7
APC 7
DBA 7
tumor progression 7
MDS/MPD 7
solid tumor 7
progressive supranuclear palsy 6
non-small cell lung cancer 6
APL 6
B-cell lymphoma 6
fits 6
CES 6
HIV 6
APL 6
lung cancer 6
lymphedema 6
tuberculosis 6
SCID 6
hepatocellular carcinoma 6
hemolytic anemia 6
hallucinations 6
osteoporosis 6
rheumatoid arthritis 6
APL 6
emotional distress 5
CSA 5
carcinogenesis 5
melanoma 5
mastocytosis 5
childhood cancer 5
pediatric AML 5
lymphoproliferative disorders 5
adult AML 5
disseminated intravascular coagulation 5
renal failure 5
infectious diseases 5
systemic lupus erythematosus 5
dyskeratosis congenita 5
MEC 5
rare disease 5
chronic leukemia 5
aspergillosis 5
vasculitis 5
hypertension 5
iron deficiency anemia 5
decubitus 5
B-ALL 5
craniosynostosis 4
Ewing's sarcoma 4
FAB M2 4
MDS-U 4
Poland 4
neuroblastoma 4
iron deficiency 4
ABL 4
more...
Symptom
tremor 21
fatigue 19
splenomegaly 17
bradykinesia 16
diarrhea 14
motor symptom 10
nausea 8
pain 8
sleepiness 7
hepatosplenomegaly 7
discomfort 7
apathy 6
constipation 6
vomiting 6
weakness 6
hypotonia 5
abdominal pain 4
dystonia 4
seizures 3
myoclonus 3
back pain 3
anorexia 3
dyspnea 3
headache 3
dysarthria 2
bone pain 2
discomfort 2
overweight 2
hypoproteinemia 2
arthralgia 2
hepatomegaly 2
functional recovery 1
Sedation 1
acute abdomen 1
hypothermia 1
chest pain 1
tinnitus 1
agitation 1
right upper quadrant pain 1
angina 1
exertional dyspnea 1
night sweats 1
torticollis 1
ophthalmoplegia 1
cough 1
HSA 1
abnormal gait 1
alexithymia 1
hoarseness 1
dizziness 1
drooling 1
eds 1
limb pain 1
erythema 1
vertigo 1
memory loss 1
pallor 1
cachexia 1
tense 1
Rest tremor 1
Ill 1
spasticity 1
bradypnea 1
consciousness disturbance 1
hemiplegia 1
forgetfulness 1
Stepping 1
fever of unknown origin 1
Drug
MDS 2225
CSF 37
G-CSF 31
Lenalidomide 18
TRM 8
Fludarabine 8
CTX 7
AraC 7
TEL 6
lysine 5
DBS 5
IL-2 5
TMS 5
Spectrum 5
ROC 5
ROS 5
Deferasirox 5
Leaf 4
ARA-C 3
Revlimid 3
Monit 3
Azacytidine 3
TTC 3
MRC 3
BLM 2
Posture 2
Dermatol 2
Vitamin K2 2
Rituximab 2
Dacogen 2
Silica 2
VCR 2
LCM 2
niacin 2
vitamin E 2
Epoetin 2
Frontal 2
Glutathione 2
Camp 2
LCM 2
anti-CD33 2
Amifostine 2
Rasagiline 2
Infliximab 1
THF 1
CPR 1
Infliximab 1
Clofarabine 1
CCL 1
CTX 1
IL-11 1
ADR 1
Istradefylline 1
Gel 1
Exelon 1
MDM 1
IPD 1
CTX 1
Asn 1
ALA 1
Imatinib 1
Sobuzoxane 1
Herceptin 1
Ranimustine 1
Prednisolone 1
Android 1
IFN-gamma 1
CPT-11 1
Bestatin 1
Bexxar 1
ABC 1
Bayer 1
Coral 1
Alvocidib 1
HCH 1
ascorbate 1
Antithymocyte globulin 1
Alliance 1
Idarubicin 1
G418 1
Posaconazole 1
Novantrone 1
FCV 1
Zevalin 1
Everolimus 1
PFA 1
Bortezomib 1
Lipiodol 1
Spectrum 1
Campath 1
Triad 1
Campath 1
Darbepoetin alfa 1
Tipifarnib 1
Exelon 1
Cardiovasc 1
GEO 1
NBT 1
Biopolymers 1
Aclarubicin 1
Starasid 1
Etoposide 1
Vitamin K 1
Neoral 1
Enzyme
focal adhesion kinase 51
ERK 49
topoisomerase 40
topoisomerase 40
BMT 39
STR 18
peroxidase 16
CD13 14
DNA methyltransferase 9
mitogen-activated protein kinase 9
MDR 6
lactate dehydrogenase 6
transcriptase 5
P-glycoprotein 5
MEK 5
alkaline phosphatase 5
reverse transcriptase 5
RNA polymerase 5
thymidine kinase 4
protein kinase C 4
caspase-3 4
neutrophil elastase 3
AMP-activated protein kinase 3
endonuclease 3
APC 3
tryptase 3
deoxyguanosine kinase 3
NQO1 3
CD10 3
protein kinase 3
PARP 3
AMPK 3
proteasome 3
thyroid peroxidase 3
NOS 3
AMPK 3
alanine aminotransferase 3
ribonucleotide reductase 3
ribonucleotide reductase 3
glutathione S-transferase 2
DAT 2
calcineurin 2
ACE 2
MPP 2
GSK 2
CYP3A4 2
cytidine deaminase 2
aspartate aminotransferase 2
trypsin 2
isocitrate dehydrogenase 2
PFI 2
isocitrate dehydrogenase 2
CAD 1
PTA 1
phosphoglycerate kinase 1
CPR 1
AST 1
granzyme B 1
CDR 1
purine nucleoside phosphorylase 1
thromboplastin 1
methionine synthase 1
ALA synthase 1
phospholipase C 1
phospholipase D 1
matrix metalloproteinase 2 1
Omi/HtrA2 1
NADPH oxidase 1
ricin 1
tyrosine hydroxylase 1
tyrosinase 1
methionine synthase 1
monoamine oxidase 1
matrix metalloproteinase 9 1
phosphatidylinositol 3-kinase 1
ornithine decarboxylase 1
beta-glucuronidase 1
glutathione synthetase 1
trypanothione reductase 1
MTD 1
HSD 1
thymidylate synthase 1
NADPH oxidase 1
cdc2 1
thymidine phosphorylase 1
PAH 1
iduronate-2-sulfatase 1
asparaginase 1
acetylcholinesterase 1
LPL 1
adenosine deaminase 1
cholinesterase 1
methylenetetrahydrofolate reductase 1
PGM 1
deoxycytidine kinase 1
HCS 1
AGT 1
dihydrofolate reductase 1
adenosine deaminase 1
fatty acid desaturase 1
HDR 1
elastase 1
riboflavin kinase 1
methylenetetrahydrofolate reductase 1
CAD 1
gamma-glutamyl transpeptidase 1
LasR 1
CPS 1
cyclohydrolase 1
lysozyme 1
glyceraldehyde-3-phosphate dehydrogenase 1
demethylase 1
cholesterol 25-hydroxylase 1
ferrochelatase 1
legumain 1
caspase-1 1
CAD 1
beta-amylase 1
thrombin 1
Compound
DNA 176
Dec 152
Clin 108
iron 50
water 47
Ara-C 27
Ara-C 24
5-Azacytidine 22
TBI 19
PDQ 19
retinoic acid 18
acetonitrile 14
DAC 13
ammonium 13
oxygen 12
acetate 11
benzene 11
His 11
hydrogen 10
DFS 10
sodium 10
MTT 9
BCR 9
5-Aza-2'-deoxycytidine 9
formic acid 8
formic acid 8
formic acid 8
formic acid 8
formic acid 8
formic acid 8
formic acid 8
formic acid 8
TNF 8
formic acid 8
formic acid 8
CTX 7
nitrogen 7
methanol 7
MDA 6
MDR 6
PEG 6
CES 6
zinc 6
TEL 6
bromide 6
phosphate 5
PAC 5
lysine 5
calcium 5
MTX 5
L-DOPA 5
VP-16 5
MEK 5
Cyclosporine 5
ITP 5
DBS 5
PEG 5
Pac 5
Methotrexate 5
glutamate 4
Off 4
glutamine 4
ABL 4
boron 4
potassium 4
iodine 4
Benzene 4
phosphorus 4
Neo 4
salt 4
DHB 4
PMA 4
ethanol 4
leucine 3
NH2 3
pyrimidine 3
methionine 3
PMA 3
phosphoric acid 3
Topotecan 3
GMP 3
PAS 3
Hydroxyurea 3
ATP 3
Topotecan 3
THP 3
CIT 3
pyrimidine 3
TOF 3
L-PAM 3
glucose 3
Yellow 3
DSM 3
DIC 3
Busulfan 3
Hemoglobin 3
tyrosine 3
CIT 3
Valproic acid 3
SDS 3
THP 3
L-PAM 3
IDA 2
proline 2
HEI 2
Mitoxantrone 2
Phe 2
TTP 2
Ural 2
HNO3 2
Diazepam 2
Menadione 2
GTP 2
carbonate 2
Amifostine 2
BLM 2
alanine 2
Gly 2
GABA 2
galactose 2
HNO3 2
PID 2
HNO3 2
HNO3 2
GABA 2
MIC 2
ADR 2
LCR 2
6-12 2
HNO3 2
GSH 2
HNO3 2
CTP 2
ammonia 2
HNO3 2
SET 2
Mitoxantrone 2
serine 2
PEI 2
HNO3 2
copper 2
Optimal 2
HNO3 2
HNO3 2
silicon 2
sulfate 2
silver 2
PEI 2
CMK 2
DFO 2
HNO3 2
PID 2
PDB 2
HNO3 2
HNO3 2
tungsten 2
GSH 2
urea 2
HNO3 2
Nitrate 2
more...