Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D03301 (PDL)
 658 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PD-1 88
Sep 50
cytokine 38
collagen 38
CD8 36
CTLA-4 30
PD-L1 29
Mol 26
CD4 26
PD1 24
IL-10 24
osteogenic 24
CD86 23
TNF 21
IFN 21
alkaline phosphatase 19
CD80 15
IL-6 15
CD25 14
CD40 14
fibronectin 13
interferon 12
BRAF 12
lymphoid 12
programmed death ligand 1 12
CTLA4 12
IFN-gamma 11
CD28 10
PGA 10
MHC 10
PI3K 9
mTOR 9
IDO 9
osteocalcin 9
PEG 9
PD-L2 9
HLA-DR 8
NMR 8
insulin 8
IL-4 8
bone sialoprotein 8
IL-2 8
Poly 8
HER2 8
osteopontin 7
LPS 7
STAT3 7
Rho 6
MEK 6
IL-17 6
Cytokine 6
ANOVA 6
VEGF 6
EGFR 6
RANKL 6
PLA 5
ICOS ligand 5
TCP 5
polypeptide 5
OX40 5
ICOS 5
vascular endothelial growth factor 5
4-1BB 5
MHC class II 5
p53 5
CD40L 5
PMD 5
type I collagen 5
CD14 5
PDL1 5
serum albumin 5
p38 5
CO2 5
lipopolysaccharide 5
IL-23 4
p65 4
superoxide dismutase 4
epidermal growth factor receptor 4
AKT 4
RANTES 4
CD163 4
osteosarcoma 4
GSH 4
PAH 4
indoleamine 2,3-dioxygenase 4
PDGF 4
TNF-alpha 4
PDL2 4
lipase 4
focal adhesion kinase 4
lectin 4
CD83 4
MAP kinase 4
lymphocyte antigen 4
ATP 4
IL-1 beta 4
MAPK 4
tumor necrosis factor 4
4-1BBL 3
FBS 3
ATR 3
MET 3
PIK3CA 3
TGF-beta 3
TIG-1 3
epidermal growth factor 3
SDS 3
amelogenin 3
CD44 3
IL-8 3
ICAM-1 3
CD200 3
proteoglycan 3
parathyroid hormone 3
San 3
RUNX2 3
NOD 3
interleukin-10 3
MHC class I 3
B7-H3 3
LAG-3 3
MSC 3
TNF-R1 3
HLA 3
receptor tyrosine kinase 3
IL-13 3
gut 3
tyrosine kinase 3
CD146 3
PCL 3
membrane protein 3
VEGFR2 3
osteoprotegerin 3
STAT 3
major histocompatibility complex 3
p40 3
CCL2 3
granzyme B 3
CD29 3
TIM-3 3
MMP-8 3
MCP-1 3
OPG 3
Ki-67 3
TLR9 3
chemokine 3
GM-CSF 3
TLR4 3
CD11b 3
histone 3
RANK 3
IPL 3
CD11c 2
TERT 2
CD206 2
ALP 2
PRL 2
caspase-3 2
ape 2
EGF 2
GTP 2
anaplastic lymphoma kinase 2
CD209 2
TLR2 2
AMP 2
FISH 2
brain-derived neurotrophic factor 2
ROS 2
axonal 2
JAK2 2
IRAK1 2
PDH 2
HLA-G 2
OSP 2
core protein 2
nitric oxide synthase 2
CD1a 2
cytokeratin 2
adhesion molecule 2
runt-related transcription factor 2 2
FOXP3 2
vascular cell adhesion molecule-1 2
CD127 2
CD70 2
glycoprotein 2
Laminin 2
brush border 2
c-Jun 2
T-bet 2
Fas 2
glutathione peroxidase 2
relaxin 2
amylase 2
ILT3 2
enamel matrix protein 2
programmed cell death 1 2
MEK1 2
CCR7 2
lactate dehydrogenase 2
type I interferon 2
MMP-1 2
SOX9 2
CXCR4 2
vitronectin 2
estrogen receptor 2
biglycan 2
collagenase 2
TTF-1 2
ERK1 2
acid phosphatase 2
GABA 2
tartrate-resistant acid phosphatase 2
chymotrypsin 2
DPP 2
IGF-I 2
TIL 2
bone morphogenetic protein 2
PLG 2
IGF-1 2
RAP 2
FasL 2
FGF 2
interferon gamma 2
BMP-2 2
casein 2
bone) 2
TLR7 2
CD69 2
dentin matrix protein 1 2
inducible nitric oxide synthase 2
KRAS 2
interferon-gamma 2
CD27 2
CCL3 2
periostin 2
ERK 2
CDK4 2
She 2
ABC 2
macrophage receptor 2
NGF 2
fused 2
thymus 2
Pseudomonas 2
GITR 2
CIITA 2
ALA 2
catenin 2
CD200R 2
interferon alpha 2
c-kit 2
YAP 2
THP 2
IL-1 2
IFI27 1
urokinase-type plasminogen activator 1
MCP-2 1
protein kinase B 1
IL17 1
p24 1
TACE 1
CCL20 1
CF2 1
IFIT1 1
C-1 1
STAT5 1
esterase 1
CRMP5 1
IL1RN 1
p38MAPK 1
LIGHT 1
Jagged1 1
beta-glucuronidase 1
RNA-binding protein 1
P2X7 1
TRAF6 1
CD95L 1
paxillin 1
Complement C3 1
Lipocalin-2 1
Fas ligand 1
Net 1
fibronectin 1 1
PDX-1 1
matrix metalloproteinase 20 1
Bfl-1 1
vinculin 1
H-ras 1
DM1 1
ras 1
neurotrophic factor 1
novel kinase 1
PLC 1
P32 1
ECM 1
CD31 1
adapter protein 1
severe combined immunodeficiency 1
platelet-derived growth factor 1
osterix 1
myosin light chain 2 1
HDAC3 1
caveolin 1
semaphorin 3A 1
EP4 1
surface antigen 1
platelet-derived 1
POSTN 1
KIR 1
TRAP 1
CD107a 1
GDF6 1
acetyl-CoA synthetase 1
COX2 1
Growth hormone 1
tPA 1
PLB 1
NGN3 1
Hua 1
elastin 1
more...
Disease
tumor 93
cancer 83
melanoma 26
periodontitis 20
metastases 13
non-small cell lung cancer 12
periodontal disease 12
PGA 11
arthrodesis 10
lung cancer 10
tumor growth 9
Blocking 9
breast cancer 9
lymphoma 9
carcinoma 8
renal cell carcinoma 8
metastatic melanoma 7
SEM 7
virus infection 6
Hodgkin's disease 6
diabetes 6
tooth loss 5
systemic lupus erythematosus 5
tumor progression 5
nephritis 5
TCP 5
adenocarcinoma 5
type 1 diabetes 5
PMD 5
squamous cell carcinoma 5
autoimmune disease 5
rheumatoid arthritis 5
Pelizaeus-Merzbacher disease 5
encephalomyelitis 5
plaque 5
infectious diseases 4
SCID 4
gastric cancer 4
carcinogenesis 4
acne vulgaris 4
osteosarcoma 4
Mycobacterium 4
hepatocellular carcinoma 4
GSH 4
primary tumor 4
HIV 4
pneumonia 4
hepatitis C 3
cold 3
chronic lymphocytic leukemia 3
chronic lymphocytic leukemia 3
hematologic malignancies 3
glioma 3
SDS 3
Hepatocellular carcinoma 3
PCL 3
acne 3
lung carcinoma 3
purpura 3
leprosy 3
toxoplasmosis 3
Melanoma 3
liver cancer 3
FBS 3
NOD 3
leukemia 3
graft-versus-host disease 3
renal cancer 3
skin cancer 3
immunodeficiency 3
arthritis 3
fibrosarcoma 2
leishmaniasis 2
Infection 2
Vesicular stomatitis 2
atherosclerosis 2
dental root 2
colorectal cancer 2
skin disease 2
Alzheimer's disease 2
histiocytic lymphoma 2
myelosuppression 2
Parkinson's disease 2
anemia 2
PSS 2
Klebsiella 2
head and neck cancer 2
liver cancer 2
cervical cancer 2
Roth 2
interstitial nephritis 2
nephrosis 2
colitis 2
angiokeratoma 2
chronic obstructive pulmonary disease 2
FHF 2
multiple sclerosis 2
PLG 2
T-cell lymphoma 2
T-cell lymphomas 2
histiocytic lymphoma 2
telangiectasia 2
Marek's disease 2
tuberculosis 2
cognitive impairment 2
hemangioma 2
psoriasis 2
encephalitis 2
Merkel cell carcinoma 2
immunotoxicity 2
aggression 2
bladder cancer 2
prostate cancer 2
bacterial infection 2
thrombocytopenia 2
influenza 2
pancreatic cancer 2
leiomyosarcoma 1
laryngeal cancer 1
hepatitis 1
PDR 1
MCF 1
immune deficiency 1
AIDS dementia complex 1
Civatte 1
immunopathology 1
Cutaneous leishmaniasis 1
agraphia 1
thyroid mass 1
rosacea 1
chronic hepatitis 1
diphtheria 1
HHT 1
Orbit 1
Metaplastic Breast Carcinoma 1
Gerstmann 1
Sjogren's syndrome 1
PSS 1
CEM 1
dysphonia 1
coronary artery disease 1
diplopia 1
ductal carcinoma 1
Necrobiosis lipoidica 1
teratoma 1
dental caries 1
EDC 1
dementia 1
B-cell chronic lymphocytic leukemia 1
lupus 1
acute pancreatitis 1
EMD 1
proliferative diabetic retinopathy 1
dysplasia 1
Posterior 1
Best 1
gingivitis 1
inflammatory bowel disease 1
COPD 1
acute myeloid leukemia 1
Persistent infection 1
tumorigenesis 1
intraocular pressure 1
cervical squamous cell carcinoma 1
Endodontic disease 1
herpes 1
lung metastases 1
retinitis 1
herpes labialis 1
salmonellosis 1
aggressiveness 1
glaucoma 1
herpes simplex 1
metastatic gastric cancer 1
sarcoidosis 1
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy 1
glioblastoma multiforme 1
Actinic cheilitis 1
SARS 1
chronic pancreatitis 1
Tumour necrosis 1
FAS 1
Allergic contact dermatitis 1
sepsis 1
liver fibrosis 1
hyperglycemia 1
Leiomyosarcoma 1
keratopathy 1
acute hepatitis 1
EBV infection 1
bone disease 1
petechiae 1
mental retardation 1
stage IIIA NSCLC 1
disorientation 1
mesothelioma 1
Spleen 1
cytomegalovirus 1
non-Hodgkin's lymphoma 1
ISM 1
adenoma 1
viral hepatitis 1
macular degeneration 1
leukoencephalopathy 1
PCS 1
Adhesion 1
laryngeal cancer 1
EMA 1
retinoblastoma 1
residual cancer 1
atopic dermatitis 1
autoimmune hemolytic anemia 1
vitamin D deficiency 1
Osteosarcoma 1
PNS 1
vitiligo 1
Ludwig 1
Osteosarcoma 1
xanthoma 1
panmyelosis 1
malaria 1
melanoma stage 1
immaturity 1
Obturation 1
osteitis 1
keratosis 1
cheilitis 1
progeria 1
recurrent laryngeal cancer 1
NS3 1
Xanthelasma palpebrarum 1
anaplastic thyroid cancer 1
warts 1
prolapse 1
retinopathy of prematurity 1
cutaneous melanoma 1
AIDS 1
Cerebral malaria 1
HCC 1
haemophilia 1
MTS 1
keratosis 1
pericardial effusion 1
ACD 1
stomatitis 1
bone cancer 1
Tension 1
renal disease 1
EDA 1
TEM 1
pulpitis 1
B-cell lymphomas 1
heart disease 1
multiple myeloma 1
laryngeal squamous cell carcinoma 1
periosteum 1
pericarditis 1
TEM 1
hepatitis B 1
HPA 1
heart failure 1
gallstones 1
PSS 1
ICP 1
CTX 1
basal cell carcinoma 1
WT1 1
Crohn's disease 1
dysphagia 1
sepsis 1
Gallbladder carcinoma 1
pleurisy 1
cholera 1
Tuberculoid leprosy 1
lupus 1
RCM 1
small cell lung cancer 1
sarcoma 1
ovarian cancer 1
SWS 1
cataract 1
myasthenia gravis 1
gastritis 1
acalculia 1
adrenocortical carcinoma 1
glucose intolerance 1
congenital disorder 1
adrenalitis 1
fear and anxiety 1
latent infection 1
cardiac tamponade 1
familial disorder 1
Autoimmune hepatitis 1
poikiloderma 1
hemiparesis 1
osteoporosis 1
gastrointestinal cancer 1
hyperkeratosis 1
carcinoma in situ 1
synovial sarcoma 1
cervical intraepithelial neoplasia 1
pancreatitis 1
cardiovascular disease 1
encephalopathy 1
uveitis 1
enophthalmos 1
agnosia 1
CAP 1
papilloma 1
HGF 1
hepatitis D 1
PAA 1
B-cell lymphoma 1
premature aging 1
mental retardation 1
TOC 1
leukopenia 1
Malassez 1
DM1 1
IMT 1
more...
Symptom
exhaustion 11
pain 10
anesthesia 6
discomfort 4
discomfort 4
hoarseness 2
erythema 2
analgesia 1
joint stiffness 1
collapse 1
seizures 1
diarrhea 1
functional recovery 1
numbness 1
paresthesia 1
stigma 1
vomiting 1
fatigue 1
starvation 1
shortness of breath 1
fasciculation 1
dyspnea 1
Drug
PDL 658
lysine 35
Dermatol 17
IFN-gamma 11
IL-2 9
Ipilimumab 4
CSF 4
Monit 3
balanced salt solution 2
Gelatin 2
ascorbate 2
ALA 2
G418 2
ABC 2
EE2 2
ROS 2
vitamin E 1
PPA 1
Activin 1
Swainsonine 1
THF 1
Pemetrexed 1
uPA 1
Papain 1
Fraction 1
Volociximab 1
Regitine 1
Bevacizumab 1
Check 1
Emla 1
CTX 1
lactose 1
Emla 1
DPA 1
Growth hormone 1
CTX 1
MAP 1
Cortrosyn 1
Cortrosyn 1
NADH 1
Singular 1
DNase I 1
Doxycycline 1
Gel 1
CTX 1
DM1 1
Emla 1
Arsenic trioxide 1
Growth hormone 1
Rituximab 1
Enzyme
ERK 20
alkaline phosphatase 19
mitogen-activated protein kinase 13
focal adhesion kinase 9
MEK 9
superoxide dismutase 5
protein kinase 5
PAH 4
lipase 4
collagenase 4
granzyme B 3
luciferase 3
indoleamine 2,3-dioxygenase 3
reverse transcriptase 3
elastase 2
trypsin 2
lactate dehydrogenase 2
acid phosphatase 2
chymotrypsin 2
catalase 2
ACE 2
glutathione peroxidase 2
PDH 2
caspase-3 2
ALDH 1
proteasome 1
laccase 1
TSA 1
glycerol dehydratase 1
gamma-glutamylcysteine synthetase 1
tryptophan 2,3-dioxygenase 1
tissue plasminogen activator 1
pepsin 1
manganese peroxidase 1
phosphodiesterase 1
MMP-3 1
xanthine oxidase 1
ricin 1
AMPK 1
CAD 1
plasmin 1
calcineurin 1
lysozyme 1
chondroitinase AC 1
ATPase 1
ACS 1
chondroitinase 1
urokinase-type plasminogen activator 1
p100 1
carnitine acetyltransferase 1
Thy1 1
cdc2 1
glucose-6-phosphate dehydrogenase 1
PARP 1
beta-glucuronidase 1
phospholipase C 1
chondroitinase 1
MAP 1
prostate-specific membrane antigen 1
matrix metalloproteinase 9 1
micrococcal nuclease 1
ethanolamine ammonia-lyase 1
CAD 1
hyaluronidase 1
FFT 1
cathepsin K 1
CAD 1
NO synthase 1
DNA polymerase 1
ascorbate peroxidase 1
peroxidase 1
TACE 1
DAT 1
Compound
Dec 49
lysine 35
Clin 33
DNA 29
TNF 21
calcium 15
water 15
phosphate 14
PEG 14
sodium 12
PEG 12
PGA 10
glycerol 9
glucose 9
MTT 9
CO2 8
adipate 7
oxygen 7
potassium 6
arginine 6
acetate 6
MEK 6
copper 5
TCP 5
zinc 5
PEI 5
TCP 5
bromide 5
TCP 5
PEI 5
TCP 5
PLA 4
Collagen 4
EDTA 4
leucine 4
PAH 4
GSH 4
ATP 4
EDTA 4
GSH 4
cAMP 4
methionine 4
tryptophan 3
silicon 3
L-leucine 3
PDT 3
SDS 3
SiO2 3
A 3 3
ASA 3
nitric oxide 3
tryptophan 3
hydrogen 3
1,3-propanediol 3
tryptophan 3
tryptophan 3
butyric acid 3
proline 3
butyric acid 3
Lactic acid 3
titanium 3
PGE2 3
butyric acid 3
Pluronic 2
Alizarin 2
ethanol 2
DEAE 2
H2O2 2
MDA 2
MTA 2
carbonate 2
PDH 2
GTP 2
vitamin D 2
Dexamethasone 2
aspartic acid 2
acrylamide 2
salt 2
hydroxide 2
glutamate 2
ALP 2
aspartic acid 2
tyrosine 2
diacetate 2
GABA 2
AMP 2
BCG 2
GABA 2
Asp 2
ABA 2
THF 2
aspartic acid 2
THP 2
Insulin 2
DMSO 2
Cortisol 2
THP 2
Estradiol 2
aluminum 2
ETH 2
HCl 2
galactose 2
ABA 2
aspartic acid 2
C28H38O7 1
DAT 1
retinol 1
iodine 1
CBS 1
DPA 1
hexose 1
Bongkrekic acid 1
cadmium 1
Salt 1
corrin 1
Arsenite 1
cobalt 1
TEA 1
TNM 1
ASE 1
phenanthrene 1
chloroform 1
DPA 1
DPA 1
PPi 1
Thymidine 1
sodium chloride 1
retinoic acid 1
formic acid 1
acetic acid 1
MAP 1
TACE 1
DPA 1
formic acid 1
TEA 1
aflatoxin B1 1
APAP 1
Tris 1
PPO 1
Withanolide E 1
CAT 1
2,3-butanediol 1
Norton 1
C28H38O7 1
GMP 1
Rhodamine B 1
formic acid 1
hexose 1
L-Lactate 1
Vimentin 1
Cytochalasin D 1
PPI 1
BzATP 1
acetaldehyde 1
20-Hydroxyecdysone 1
MBT 1
A 1 1
2,3-butanediol 1
acetonitrile 1
aldehyde 1
Estrogen 1
phosphorus 1
Adenosine 1
Ethionine 1
Inosine 1
NADPH 1
BOP 1
urea 1
C11H11NO5 1
NAD 1
ETH 1
formic acid 1
PMA 1
Swainsonine 1
NADH 1
formic acid 1
iron 1
TEM 1
MTS 1
Pyruvate 1
ITP 1
PPA 1
triphenylphosphine 1
HEMA 1
DQ1 1
Sucrose 1
ADR 1
TCA 1
phenol 1
tert-butyl hydroperoxide 1
formic acid 1
FK506 1
molybdenum 1
formic acid 1
ACS 1
CTX 1
Estrogen 1
Triamcinolone 1
EDC 1
Neuronal 1
NAD 1
Lactate 1
DPA 1
CAM 1
PAA 1
Doxycycline 1
Triamcinolone acetonide 1
DPA 1
DPA 1
nitrogen 1
Valproic acid 1
DLA 1
TAR 1
CAP 1
Nodular 1
THF 1
threonine 1
Fosfomycin 1
1H-indole 1
SCC 1
Fibrin 1
Phe 1
nitrate 1
Pyruvate kinase 1
hydroxyglutarate 1
TXA2 1
nickel 1
ACS 1
D-glucuronic acid 1
Trypsin 1
ACTH 1
PVA 1
CAT 1
hexose 1
COX 1
PPA 1
Abbott 1
glutamine 1
DPA 1
aldosterone 1
formic acid 1
PMA 1
formic acid 1
cGMP 1
2,3-butanediol 1
propionaldehyde 1
betaine 1
methylformamide 1
DMF 1
CAP 1
DPA 1
Calcitonin 1
Gentamicin 1
Pac 1
glutamic acid 1
PPD 1
Biliverdin 1
DPA 1
6-12 1
C28H38O7 1
adenosylmethionine 1
tungsten 1
Adriamycin 1
PPD 1
hydroxylamine 1
DPA 1
formic acid 1
fluorine 1
sulfate 1
PHB 1
TMB 1
DPA 1
vinyl acetate 1
Tris 1
H2S 1
NADPH 1
CAT 1
Brilliant Blue 1
hydroxylamine 1
Optimal 1
Alginate 1
hexose 1
toluene 1
Chitosan 1
Thyroid 1
strontium 1
Sodium 1
Tween 80 1