Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D03276 (Parkin)
 1,863 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
BNIP3L protein 14.1
Parkin 2 14.1
Parkin 14.1
parkin isoform 13.1
C7orf13 13.1
PINK1 12.9
ZNF746 12.9
USP30 12.9
RING2 12.6
RING-IBR 12.5
synaptotagmin XI 12.5
DnaJ/Hsp40 chaperone 12.5
PARK6 12.3
PARK2 12.2
parkin 12.2
NMDMC 12.1
RAB9B 12.1
FBX 11.8
synphilin-1A 11.7
apoptosis facilitator 11.7
F-box and WD40 domain protein 7 11.7
PARKIN 11.7
RING1 11.6
Inhibitory PAS domain protein 11.6
HRD1 protein 11.6
CUL9 11.6
synphilin-1 11.6
SPAG16L 11.5
TBC1D17 11.5
RNF32 11.5
microtubule-associated proteins 1A/1B light chain 3 11.5
PNUTL2 11.5
FBXO7 11.5
PMPCB 11.5
PACRG 11.4
Synphilin-1 11.3
ATP13A2 protein 11.3
VPS13C 11.3
SYNJ1 11.3
MARCH5 11.2
more...
Disease
Juvenile Parkinsonism 12.6
PARK6 12.4
PARK2 12.2
PARK1 11.8
PARK4 11.6
PARK3 11.0
PARK5 10.7
cerebral cancer 10.7
22q deletion syndrome 10.3
PARK8 10.1
KRS 9.9
PARK11 9.8
immature personality 9.7
IBR 9.4
PARK7 9.3
OPA1 9.0
IBMPFD 8.6
parkinsonism 8.4
nervous disorder 8.2
Complex I deficiency 8.1
XDP 8.1
Parkinson's disease 8.0
ARTS 7.8
Metastatic colorectal cancer 7.6
Dubowitz 7.5
sphingolipidosis 7.4
SPG11 7.3
Oppenheim 7.2
SCA2 6.9
movement disorder 6.8
RDP 6.8
Alcoholic liver disease 6.8
camptocormia 6.8
Diabetic peripheral neuropathy 6.6
hemiparkinsonism 6.6
UIP 6.6
PDR 6.5
Dementia with Lewy bodies 6.4
MERRF 6.4
primary lateral sclerosis 6.3
more...
Symptom
Dribbling 9.8
acid regurgitation 6.7
bradykinesia 5.7
dystonia 4.7
hypersomnia 4.0
tremor 4.0
starvation 3.8
memory loss 3.8
muscle stiffness 3.8
anosmia 3.5
hyperoxia 3.3
cachexia 3.2
dysarthria 3.2
myoclonus 3.0
collapse 3.0
ataxia 2.4
cerebellar ataxia 2.2
functional recovery 1.9
acute stress 1.9
lethargy 1.6
weakness 1.2
hypothermia 1.0
respiratory distress 0.8
low back pain 0.8
insomnia 0.7
sleepiness 0.4
exhaustion 0.3
fatigue -0.0
seizures -0.2
diarrhea -1.8
pain -1.9
Drug
Parkin 14.1
Parkin 14.1
Formycin 10.3
Demerol 8.6
Madopar 8.2
Ioversol 8.2
Demerol 8.0
Jujube 7.9
3-Methyladenine 7.7
Nexavar 7.3
Florfenicol 6.9
Vitamin K2 6.8
Sinemet 6.3
Liraglutide 6.3
Sinemet 6.2
IPD 5.8
Colombo 5.7
Artesunate 5.6
RFP 5.4
ROS 5.3
Sinemet 5.0
CED 4.9
CFT 4.9
Kainic acid 4.7
OTC 4.5
Xanthium 4.4
DBS 4.3
TAK 4.1
OTC 4.0
TAT 3.8
Vitamin B12 3.8
Nitric Oxide 3.7
Alliance 3.7
Bortezomib 3.5
Sorafenib 3.5
Heme 3.5
ADM 3.4
ADR 3.1
Glycerol 2.9
Silica 2.8
more...
Enzyme
AMP nucleosidase 10.2
ubiquitin-protein ligase 9.8
nucleoside hydrolase 9.3
rhomboid protease 8.9
Omi/HtrA2 8.8
MPP 7.2
isopeptidase 6.9
glucocerebrosidase 6.9
proteasome 6.5
SNO 6.5
methylmalonyl-CoA mutase 6.4
complex I 6.3
AMPK 6.2
inositol 3-kinase 6.2
pantothenate kinase 6.1
carbonyl reductase 6.0
adrenodoxin reductase 5.9
AMP-activated protein kinase 5.8
phosphoglycerate dehydrogenase 5.7
MsrA 5.7
aconitase 5.6
AMPK 5.3
PHD 5.3
choline kinase 5.3
PGM 5.2
phosphoribulokinase 5.0
IKK 5.0
HK2 4.9
branching enzyme 4.8
citrate synthase 4.7
poly(A) polymerase 4.7
neutral sphingomyelinase 4.7
phosphatidylinositol 4-kinase 4.7
DAT 4.5
insulin-degrading enzyme 4.5
tyrosine hydroxylase 4.5
triphosphatase 4.5
polo-like kinase 1 4.5
ClpP 4.5
caspase-2 4.5
more...
Compound
Vasicinone 11.5
NIX 11.5
C23H22O6 11.3
IPAS 9.6
Rocaglamide 9.4
Tributyrin 8.4
Notoginsenoside R1 8.3
Alantolactone 8.3
Palmatine 8.2
L-chicoric acid 8.1
CHIP 8.0
CCP 8.0
3-Methyladenine 7.7
1-Methyl-4-phenylpyridinium 7.6
Sesamin 7.6
Paricalcitol 7.3
MPP 7.2
MPP 7.2
Ubiquitin 7.1
TRU 7.0
MPTP 6.9
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 6.9
Valinomycin 6.8
CUE 6.6
Elan 6.5
Monocrotaline 6.5
Sanguinarine 6.5
Genipin 6.4
Rotenone 6.4
Elan 6.2
1,2,3,6-tetrahydropyridine 6.2
Lipoxin A4 6.2
1,2,3,6-tetrahydropyridine 6.2
Matrine 6.2
Matrine 6.2
Matrine 6.2
Fisetin 6.1
CPH 6.0
Ephedrine 6.0
IAS 6.0
more...