Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: KEGG:D03276 (Parkin)
1,863 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Parkin 1863 PINK1 586 ubiquitin 374 parkin 359 E3 ubiquitin ligase 235 Mol 222 PTEN 184 proteasome 155 PARK2 141 DJ-1 138 LC3 134 ubiquitin ligase 127 p62 116 alpha-synuclein 108 Sep 98 LRRK2 94 synuclein 84 ATP 82 endoplasmic reticulum 75 PARKIN 64 outer mitochondrial membrane 56 PARK6 53 ROS 45 p53 45 PGC 44 ubiquitin-protein ligase 43 SNCA 39 axonal 39 Bcl-2 38 PDB 38 dynamin-related protein 1 38 Ubiquitin 37 glucocerebrosidase 35 mTOR 35 caspase-3 34 Nix 31 PARK7 30 LC3B 30 BNIP3 30 interacting protein 28 more...

Disease Parkinson's disease 914 parkinsonism 277 PARK2 141 cancer 108 Alzheimer's disease 78 tumor 69 ischemia 42 neuroblastoma 38 PARK6 32 dementia 32 movement disorder 30 amyotrophic lateral sclerosis 26 diabetes 22 tumorigenesis 22 OPA1 20 lung cancer 18 type 2 diabetes 15 GSH 15 IBR 13 hepatocellular carcinoma 13 depression 12 cognitive impairment 12 heart failure 11 obesity 11 Huntington's disease 11 tumor growth 10 sepsis 10 PARK7 10 breast cancer 10 sepsis 10 stroke 10 PARK1 9 cerebral ischemia 9 myocardial infarction 8 tumor progression 8 gastric cancer 8 Dementia with Lewy bodies 8 neuropathy 8 infectious diseases 8 myocardial ischemia 8 more...

Symptom starvation 21 tremor 17 dystonia 13 collapse 13 bradykinesia 7 weakness 5 ataxia 5 pain 4 seizures 4 functional recovery 3 cachexia 3 memory loss 3 fatigue 3 hyperoxia 3 respiratory distress 2 myoclonus 2 dysarthria 2 hypothermia 2 diarrhea 1 Dribbling 1 muscle stiffness 1 insomnia 1 anosmia 1 exhaustion 1 lethargy 1 acid regurgitation 1 low back pain 1 acute stress 1 cerebellar ataxia 1 sleepiness 1 hypersomnia 1

Drug Parkin 1863 Parkin 1863 ROS 45 lysine 22 Monit 6 Cardiovasc 4 RFP 3 Madopar 2 Nitric Oxide 2 NADH 2 ADM 2 Heme 2 3-Methyladenine 2 TAT 2 Alliance 2 Liraglutide 2 ADR 1 Florfenicol 1 CFT 1 Jujube 1 TiO2 1 Alanine 1 Nephron 1 Sorafenib 1 HCH 1 OTC 1 Kainic acid 1 Formycin 1 CED 1 OTC 1 Indomethacin 1 Nexavar 1 Vitamin B12 1 TAK 1 Demerol 1 SiO2 1 Xanthium 1 Sinemet 1 Sinemet 1 DBS 1 more...

Enzyme proteasome 155 protein kinase 56 AMP-activated protein kinase 44 ubiquitin-protein ligase 43 complex I 42 mitogen-activated protein kinase 32 AMPK 29 AMPK 28 caspase-3 23 superoxide dismutase 22 tyrosine hydroxylase 20 ATPase 16 MPP 16 calcineurin 14 luciferase 10 glucocerebrosidase 10 nucleoside hydrolase 10 Omi/HtrA2 9 caspase-9 9 catalase 9 IKK 9 ATP synthase 8 lactate dehydrogenase 8 PARP 8 citrate synthase 7 succinate dehydrogenase 7 ERK 7 glutathione peroxidase 6 kinesin 6 GSK 5 protein kinase C 5 caspase-1 5 aconitase 5 isopeptidase 4 alanine aminotransferase 4 glutathione S-transferase 4 APC 4 ACS 4 aspartate aminotransferase 3 rhomboid protease 3 more...

Compound oxygen 190 Dec 126 DNA 119 ATP 82 glucose 48 calcium 40 MPTP 37 cyanide 36 cysteine 31 serine 29 lysine 29 CCP 25 Clin 24 hydrogen 22 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 22 threonine 22 Ubiquitin 21 TNF 20 iron 20 NIX 18 zinc 18 nitric oxide 17 water 17 leucine 15 GSH 15 GSH 15 MPP 15 MPP 15 CHIP 13 L-DOPA 12 glutamate 12 nitrogen 12 manganese 11 Melatonin 11 His 9 AMP 9 Neuronal 9 boron 9 MTT 9 phosphate 8 more...

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