Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D03229 (
BLM
)
1,348
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
BLM
1264
helicase
364
WRN
203
Bloom syndrome
169
Mol
123
DNA helicase
113
Sep
95
RECQL4
73
BRCA1
57
p53
56
ATM
52
RAD51
51
BLM protein
48
CHOP
47
telomeric
47
RMI1
46
Werner syndrome
46
ATP
46
BRCA2
35
ATR
31
more...
Disease
BLM
1264
cancer
426
WRN
210
tumor
194
melanoma
63
ATM
61
RTS
56
lymphoma
55
premature aging
47
immunodeficiency
46
pulmonary fibrosis
46
genetic disorder
45
anemia
42
Fanconi
37
breast cancer
33
carcinoma
32
tumorigenesis
32
non-Hodgkin's lymphoma
28
metastases
26
idiopathic pulmonary fibrosis
22
more...
Symptom
collapse
10
erythema
7
pain
3
nausea
2
chest pain
2
diarrhea
2
hemoptysis
2
dyspnea
2
Anoxia
1
hypothermia
1
flank pain
1
lassitude
1
ophthalmoplegia
1
anesthesia
1
anorexia
1
vomiting
1
cachexia
1
sleepiness
1
ataxia
1
thinning
1
more...
Drug
BLM
1348
VCR
25
ADM
22
VCR
20
ADR
13
Adriamycin
10
CPM
9
CTX
8
caffeine
7
lysine
7
Dermatol
7
ACT
6
ROS
4
Mutagen
4
CTX
3
CTX
3
Blenoxane
3
Etoposide
3
MDS
2
CPT-11
2
more...
Enzyme
topoisomerase
58
topoisomerase
58
ATPase
31
endonuclease
30
PARP
13
superoxide dismutase
11
DNA polymerase
10
mitogen-activated protein kinase
9
CPM
9
focal adhesion kinase
9
ERK
8
protein kinase
6
alanine aminotransferase
6
APC
6
cdc2
5
phospholipase C
5
protein kinase C
5
RNA polymerase
5
catalase
4
glutathione peroxidase
4
more...
Compound
BLM
1347
DNA
638
Dec
85
ATP
46
water
42
Clin
31
MMC
31
calcium
29
Methotrexate
26
MTX
24
oxygen
23
5-FU
21
methyl methanesulfonate
21
iron
18
copper
17
hydrogen
17
sodium
16
BBM
13
ADR
13
VP-16
12
more...