Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D02598 (Infliximab)
 1,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
LRRC31 13.2
IL12R 10.4
p75 TNF receptor 10.3
TSA2 10.1
FKBP1A 9.7
HLA-B52 9.5
FGF12 9.1
AKR1D1 9.1
chemokine receptor CCR9 9.0
TNF receptor type 2 8.8
HLA-A26 8.8
DDAH-1 8.8
HLA-B51 8.7
Gamma-glutamyltransferase 8.7
IL12RB2 8.7
CARD15 8.7
ankylosing spondylitis 8.6
DDAH1 8.6
GCD 8.3
CNI 8.3
TNFRSF1B 8.1
Ly-6E 8.1
IBD 8.0
Matrix metalloproteinase 9 8.0
ITGB2 8.0
Tumor necrosis factor 7.9
DLT 7.8
lymphotoxin alpha 7.7
insulin receptor substrate-2 7.6
TNF-alpha converting enzyme 7.6
ACT2 7.6
TED 7.6
HLA B 7.5
TNG 7.5
JIP 7.5
Tumor necrosis factor alpha 7.5
ANO1 7.5
MMP-11 7.3
PAPA 7.3
thiopurine S-methyltransferase 7.3
TNF receptor 7.2
CDP 7.2
matrix metalloproteinase 3 7.2
TNF-R1 7.0
tumor necrosis factor alpha 7.0
IL-20 7.0
TNF-alpha 6.9
CD52 6.9
TNF 6.8
serum amyloid A protein 6.8
tumor necrosis factor 6.8
P70S6K 6.7
IL23R 6.6
MPS VI 6.6
peroxisome proliferator activated receptor gamma 6.6
CCP 6.6
p75 6.6
GCP 6.5
NAP1 6.5
TNF-a 6.4
ACT1 6.4
immunoglobulin kappa 6.4
MTX 6.3
DICER1 6.2
Fractalkine 6.2
TNFR2 6.2
wich 6.2
CCR9 6.2
IRIS 6.1
HCP 6.1
IL-11 6.1
ICAM-2 6.1
HSE 6.1
PTK 6.0
4-1BBL 6.0
VDR mRNA 6.0
MHC class II antigen 6.0
NOD2 6.0
CXCL16 6.0
IMPACT 6.0
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Disease
Vulval Crohn's disease 13.2
Lupus-like syndrome 13.0
Perianal Crohn's disease 11.8
Skin induration 11.6
Indeterminate colitis 11.0
drug induced lupus 10.5
Phlegmonous gastritis 10.1
EIM 10.1
lupus pernio 10.1
Erythrodermic psoriasis 9.9
Acne fulminans 9.8
Autoimmune enteropathy 9.8
Pathergy 9.7
Latent tuberculosis 9.6
Granulomatous interstitial nephritis 9.6
Retinal vasculitis 9.5
melanoma stage 9.4
Witts 9.4
Plaque psoriasis 9.3
Nail psoriasis 9.2
Acute anterior uveitis 9.2
psoriatic arthritis 9.1
Toxic megacolon 9.1
Chronic arthritis 9.0
Crohn's disease 9.0
pyoderma gangrenosum 8.9
small bowel lymphoma 8.9
relapsed CML 8.9
Neurosarcoidosis 8.8
Inflammatory disease 8.8
Acute transverse myelitis 8.7
Bone marrow edema 8.6
ankylosing spondylitis 8.6
Generalized pustular psoriasis 8.5
Hallopeau 8.5
Pneumocystis jiroveci pneumonia 8.4
Generalized pustular psoriasis 8.4
Multifocal motor neuropathy 8.4
SAPHO syndrome 8.3
Tubulointerstitial nephritis 8.3
proctosigmoiditis 8.2
ulcerative colitis 8.2
Pityriasis rubra pilaris 8.2
infectious colitis 8.0
nail disease 8.0
spondyloarthropathy 8.0
Cogan 8.0
Collagenous colitis 8.0
serum sickness 8.0
Tumour necrosis 8.0
autoimmune vasculitis 7.9
Crohn's colitis 7.9
inflammatory bowel disease 7.9
Cardiac sarcoidosis 7.9
Marburg virus disease 7.8
Pouchitis 7.8
dactylitis 7.7
Spondyloarthritis 7.7
other autoimmune disease 7.7
Granuloma annulare 7.7
ileitis 7.7
episcleritis 7.6
hidradenitis 7.6
Steinbrocker 7.6
psoriasis 7.5
Still's disease 7.5
Behcet's disease 7.5
Hidradenitis suppurativa 7.5
Lymphomatoid papulosis 7.4
VES 7.4
scleredema 7.4
Clostridium difficile colitis 7.4
enthesitis 7.3
interstitial keratitis 7.2
Colitis 7.2
dacryoadenitis 7.1
PAPA 7.1
rheumatoid arthritis 7.1
erythema nodosum 7.0
proctitis 7.0
more...
Symptom
Nuchal rigidity 10.8
painful swallowing 8.7
anal pain 6.9
swollen joints 6.7
Spots 6.0
tenesmus 5.9
hyperesthesia 5.7
blurred vision 5.3
arthralgia 5.3
Hudson 4.7
hypoproteinemia 4.6
abdominal pain 4.4
sore throat 4.3
chills 4.3
photophobia 4.2
despair 4.1
diarrhea 4.1
fever of unknown origin 3.8
chorea 3.7
nausea 3.7
erythema 3.4
shoulder pain 3.3
knee pain 3.3
cachexia 3.3
snoring 3.3
hemoptysis 3.2
acute abdomen 3.2
bone pain 3.2
dizziness 3.1
epigastric pain 3.0
headache 3.0
Ill 2.9
dysarthria 2.9
cough 2.8
hepatosplenomegaly 2.7
anorexia 2.6
paresthesia 2.5
shortness of breath 2.4
discomfort 2.3
thinning 2.3
lethargy 2.3
back pain 2.2
discomfort 2.2
vertigo 2.0
tremor 1.6
dyspnea 1.6
respiratory distress 1.5
constipation 1.5
weakness 1.2
sleepiness 1.1
fatigue 1.1
pain 1.0
ataxia 0.8
vomiting 0.8
chest pain 0.7
collapse -0.0
anesthesia -1.0
seizures -1.5
Drug
Infliximab 14.8
Infliximab 14.8
Lenercept 12.8
Adalimumab 12.5
Visilizumab 12.0
Nalfurafine hydrochloride 12.0
Abetimus sodium 11.8
Paclitaxel poliglumex 11.3
Certolizumab pegol 11.2
Trospium 11.2
Pitavastatin calcium 10.9
Acthar 10.9
Golimumab 10.8
Thymalfasin 10.7
Abatacept 10.6
Anakinra 10.6
Tamsulosin hydrochloride 10.6
Efalizumab 10.5
Dexmedetomidine hydrochloride 10.5
Efalizumab 10.5
Peginterferon alfa-2b 10.3
Peginterferon alfa-2b 10.3
Alefacept 10.1
Basiliximab 10.0
Basiliximab 10.0
Arava 9.8
Methotrexat 9.7
Escitalopram oxalate 9.7
Daclizumab 9.6
Epratuzumab 9.5
Januvia 9.5
Chantix 9.3
Somatropin 9.3
Silodosin 9.1
Ziagen 9.0
Natalizumab 9.0
Rosuvastatin calcium 8.8
p75 8.7
Bexxar 8.6
Fosamax 8.6
Levitra 8.6
Mepolizumab 8.4
Tocilizumab 8.4
Ketalar 8.3
Pegasys 8.2
Insulin glargine 8.2
Belimumab 8.2
IL-1ra 8.2
Novantrone 8.1
Budesonide 8.1
Lipitor 8.0
Lipitor 8.0
Dutasteride 7.9
Belatacept 7.9
Zevalin 7.8
Rituximab 7.8
Sunitinib malate 7.6
Acitretin 7.6
Abciximab 7.5
Bevacizumab 7.5
Teriparatide 7.4
Herceptin 7.3
Filgrastim 7.3
Gemzar 7.2
Cetuximab 7.2
Filgrastim 7.1
Ipilimumab 7.1
Ranibizumab 7.1
Palivizumab 7.1
Tarceva 7.0
Entecavir 7.0
Entecavir 7.0
Mesalazine 7.0
FCV 6.9
Valsartan 6.9
Pirfenidone 6.9
Zoledronic acid 6.8
Prednisone 6.8
Magnesium sulfate 6.8
CDP 6.6
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Enzyme
thiopurine methyltransferase 6.7
peptidylarginine deiminase 6.3
dihydroorotate dehydrogenase 5.8
dihydroorotate dehydrogenase 5.8
SPT 5.7
p80 5.7
TSP-1 5.0
SPT 5.0
MMP-3 4.6
21-hydroxylase 4.6
CPS 4.5
indoleamine 2,3-dioxygenase 4.3
PNGase F 4.2
MMP 3.7
TAT 3.6
MIP 3.5
MAP 3.5
CDR 3.5
hypoxanthine-guanine phosphoribosyltransferase 3.5
AST 3.2
aspartate aminotransferase 3.2
aldehyde dehydrogenase 3.1
aldolase 3.0
alanine aminotransferase 2.9
hyaluronidase 2.6
adenosine deaminase 2.5
adenosine deaminase 2.4
glutathione peroxidase 2.4
collagenase 2.2
hyaluronidase 2.2
caspase-1 2.2
CYP3A4 2.1
papain 2.1
caspase-8 2.0
caspase-9 1.9
xanthine oxidase 1.7
calcineurin 1.7
phosphodiesterase 1.6
transcriptase 1.6
phosphatidylinositol 3-kinase 1.3
superoxide dismutase 1.3
AMP-activated protein kinase 1.1
P-glycoprotein 1.1
peroxidase 0.8
RNA polymerase 0.7
caspase-3 0.7
ACE 0.6
trypsin 0.4
glutathione S-transferase 0.3
ERK 0.2
lactate dehydrogenase -0.1
mitogen-activated protein kinase -0.2
thrombin -0.2
renin -0.3
luciferase -0.4
focal adhesion kinase -0.6
catalase -1.0
Compound
Etanercept 11.9
Cipralex 11.8
Rabeprazole sodium 10.7
Olsalazine 9.6
Azathioprine 8.8
6-Mercaptopurine 8.4
Sulfasalazine 8.3
Deoxyspergualin 8.3
Mesalamine 8.2
Latrunculin B 8.1
Candesartan cilexetil 8.0
Rabeprazole 7.9
6-Thioguanine 7.7
Ethambutol 7.6
Glimepiride 7.6
Solu-Medrol 7.5
Leflunomide 7.4
Temsirolimus 7.4
Tumor Necrosis Factor 7.3
Risedronate 7.3
11-dehydro-thromboxane 7.2
HAQ 7.2
Methotrexate 7.1
CDP 7.1
Bepridil 7.1
Eplerenone 7.1
Hydroxychloroquine 6.9
TNF 6.8
Irbesartan 6.7
Magnesium sulfate 6.7
Chlorambucil 6.6
Trimethoprim 6.6
Mycophenolate mofetil 6.6
Magnesium sulfate 6.6
Psoralen 6.5
Prednisone 6.4
ADMA 6.4
MTX 6.3
Neo 6.3
Sotalol 6.1
Pentoxifylline 6.1
HCP 6.0
BAS 5.9
Sertraline 5.9
Allergan 5.8
Telmisartan 5.8
Capecitabine 5.8
Sulfamethoxazole 5.7
Tigecycline 5.7
HCP 5.7
Abbott 5.7
CCP 5.7
Cyclosporine 5.6
Alendronate 5.6
pentosidine 5.5
Clarithromycin 5.4
Diphenhydramine 5.4
Tramadol 5.4
Prednisolone 5.3
Methylprednisolone 5.1
Purine 4.9
Celecoxib 4.9
Octreotide 4.8
Acyclovir 4.8
Rifampicin 4.7
Ciprofloxacin 4.7
FK506 4.6
AAF 4.4
Docetaxel 4.4
Gemcitabine 4.1
Gemcitabine 4.1
Metformin 4.1
Metformin 4.0
NIDA 4.0
Chloroquine 3.9
Chloroquine 3.9
ANCA 3.9
ATF 3.9
Tween 20 3.8
Colchicine 3.8
more...