Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D02596 (Tocilizumab)
 425 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
interleukin-6 143
IL-6 116
cytokine 92
Sep 36
C-reactive protein 33
TNF 31
tumor necrosis factor 29
SARS 18
interleukin 6 15
IL6 14
CRP 13
IL6R 13
She 12
insulin 11
CD19 10
sIL-6R 9
collagen 7
Mol 7
IL-8 7
gp130 7
more...
Disease
rheumatoid arthritis 167
arthritis 59
cancer 26
SARS 25
pneumonia 23
Castleman's disease 21
giant cell arteritis 20
vasculitis 19
tumor 15
systemic lupus erythematosus 14
neutropenia 13
thrombocytopenia 13
anemia 12
lymphadenopathy 11
rash 10
Still's disease 10
diabetes 10
amyloidosis 9
Crohn's disease 8
Cytokine release syndrome 8
more...
Symptom
respiratory distress 15
fatigue 10
pain 10
hepatosplenomegaly 7
arthralgia 5
dyspnea 5
splenomegaly 4
headache 4
diarrhea 3
night sweats 3
cough 3
anorexia 2
abdominal pain 2
sore throat 2
angina 2
intestinal bleeding 1
hip pain 1
swollen joints 1
seizures 1
hoarseness 1
more...
Drug
Tocilizumab 425
Abatacept 18
Adalimumab 14
Bortezomib 13
IL-1ra 13
Anakinra 13
Rosuvastatin calcium 12
Bevacizumab 12
Everolimus 12
Pemetrexed disodium 11
Rituximab 11
Sorafenib 11
Ezetimibe 11
Pegasys 11
Gleevec 10
Pregabalin 10
Sunitinib malate 10
Gefitinib 9
Peginterferon alfa-2b 9
Denosumab 9
more...
Enzyme
GSK 6
mitogen-activated protein kinase 5
catalase 3
lactate dehydrogenase 2
alanine aminotransferase 2
superoxide dismutase 2
CYP3A4 2
focal adhesion kinase 2
caspase-1 2
ACS 2
ERK 2
MMP-3 1
MEK 1
MDP 1
AOR 1
NADPH oxidase 1
neutrophil elastase 1
lactic acid dehydrogenase 1
aspartate aminotransferase 1
dihydropyrimidine dehydrogenase 1
more...
Compound
Clin 81
Dec 35
TNF 31
Methotrexate 16
sodium 13
Aripiprazole 11
salt 10
bromide 10
Lopinavir 9
DNA 8
oxygen 8
acetate 7
Paclitaxel 7
MTX 6
5-Azacytidine 6
PEG 6
potassium 6
Emtricitabine 6
Etanercept 6
5-Aza-2'-deoxycytidine 5
more...