KEGG:D02165 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: KEGG:D02165 (Docetaxel)
1,764 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
Sep	103
Mol	70
epidermal growth factor receptor	45
PC3	44
prostate-specific antigen	43
PC-3	42
HER2	39
granulocyte colony-stimulating factor	38
Bcl-2	33
P-glycoprotein	32
p53	31
caspase-3	31
androgen receptor	28
PSA	27
PEG	23
tyrosine kinase	23
G-CSF	23
albumin	18
bcl-2	17
NMR	16
PLA	16
annexin V	15
TAG-1	15
EGFR	15
CYP3A4	14
PCL	14
beta-tubulin	14
granulocyte	13
neu	13
AKT	12
C18	12
p21	11
JNK	11
CD44	11
cytochrome P450	11
P-gp	11
MRI	11
vascular endothelial growth factor	11
ABCB1	10
survivin	10
CYP3A	9
glycoprotein	9
PI3K	9
She	9
topoisomerase I	8
E-cadherin	8
San	8
MDR1	8
GTP	8
prostate specific antigen	8
DCF	8
lactate dehydrogenase	8
PARP	8
cytochrome	7
cytokine	7
VEGF	7
glutathione peroxidase	7
erbB-2	7
CD133	7
ATP	7
caspase-9	6
ERK	6
ACS	6
STAT3	6
Ki-67	6
TNF	6
PBS	6
estrogen receptor	6
MAPK	6
Poly	6
ERK1	6
CYP1B1	5
caspase-8	5
alkaline phosphatase	5
HNSCC	5
folate receptor	5
EGF receptor	5
GSH	5
vascular endothelial growth factor receptor	5
cage	5

Disease
cancer	666
tumor	421
breast cancer	335
prostate cancer	326
neutropenia	261
lung cancer	167
non-small cell lung cancer	155
metastatic breast cancer	145
metastases	110
tumor growth	94
carcinoma	79
gastric cancer	71
adenocarcinoma	70
ovarian cancer	61
MCF	59
lung carcinoma	59
squamous cell carcinoma	51
myelosuppression	42
anemia	33
leukopenia	29
peripheral neuropathy	29
thrombocytopenia	29
melanoma	29
tumor progression	28
PSA	27
head and neck cancer	27
stomatitis	27
neuropathy	26
bone metastases	22
primary tumor	20
esophageal cancer	20
small cell lung cancer	20
liver metastases	20
leukemia	19
esophageal cancer	19
Febrile neutropenia	17
rash	17
onycholysis	16
hormone refractory prostate cancer	16
measurable disease	16
epithelial ovarian cancer	16
esophagitis	15
pneumonia	14
PCL	14
sensory neuropathy	13
glioma	12
colorectal cancer	12
Prostate Cancer	11
congestive heart failure	11
sepsis	10
hand-foot syndrome	10
tumorigenesis	10
sepsis	10
cervical cancer	9
agranulocytosis	9
pancreatic cancer	8
SCID	8
interstitial pneumonia	8
sarcoma	8
carcinogenesis	7
recurrent breast cancer	7
metastatic gastric cancer	7
bladder cancer	7
recurrent NSCLC	7
Leukemia	7
hypertension	7
stage III NSCLC	7
scleroderma	6
hepatocellular carcinoma	6
colon cancer	6
mammary tumor	6
epiphora	6
liver cancer	6
hyperglycemia	6
respiratory failure	5
tumor angiogenesis	5
dermatitis	5
GSH	5
DDP	5
prostatic adenocarcinoma	5

Enzyme
ERK	68
prostate-specific antigen	40
P-glycoprotein	32
mitogen-activated protein kinase	24
caspase-3	24
luciferase	17
CYP3A4	14
protein kinase	13
PARP	10
topoisomerase	10
topoisomerase	10
focal adhesion kinase	9
lactate dehydrogenase	8
DCF	8
glutathione peroxidase	7
alanine aminotransferase	7
ACS	6
thymidine phosphorylase	6
alkaline phosphatase	5
MDR	5
superoxide dismutase	4
thymidylate synthase	4
caspase-9	4
AMPK	4
AMP-activated protein kinase	4
phosphodiesterase	4
AMPK	4
catalase	3
proteasome	3
MEK	3
thrombin	3
kinesin	3
SPC	3
protein kinase C	3
caspase-8	3
cdc2	3
prostate-specific membrane antigen	3
caspase-2	3
NADPH oxidase	3
reverse transcriptase	3
aspartate aminotransferase	3
NADPH oxidase	3
MTD	3
caspase-2	3
hepsin	2
hyaluronidase	2
asparaginase	2
hyaluronidase	2
DNA methyltransferase	2
NOS	2
IKK	2
hepsin	2
collagenase	2
TAT	1
AST	1
APC	1
lipase	1
urokinase-type plasminogen activator	1
endonuclease	1
CPT	1
ALDH	1
creatine kinase	1
PDE	1
DNA polymerase	1
dihydropyrimidine dehydrogenase	1
Alternating	1
phospholipase C	1
CPT	1
ATPase	1
glyceraldehyde-3-phosphate dehydrogenase	1
polo-like kinase 1	1
DNase II	1
ribonucleotide reductase	1
phospholipase A2	1
ribonucleotide reductase	1
aldolase	1
GSK	1
carbonic anhydrase	1
PAM	1
CPM	1