Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D02165 (
Docetaxel
)
1,764
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
103
Mol
70
epidermal growth factor receptor
45
PC3
44
prostate-specific antigen
43
PC-3
42
HER2
39
granulocyte colony-stimulating factor
38
Bcl-2
33
P-glycoprotein
32
p53
31
caspase-3
31
androgen receptor
28
PSA
27
PEG
23
tyrosine kinase
23
G-CSF
23
albumin
18
bcl-2
17
PLA
16
NMR
16
TAG-1
15
annexin V
15
EGFR
15
PCL
14
CYP3A4
14
beta-tubulin
14
granulocyte
13
neu
13
C18
12
AKT
12
CD44
11
P-gp
11
cytochrome P450
11
JNK
11
MRI
11
vascular endothelial growth factor
11
p21
11
ABCB1
10
survivin
10
more...
Disease
cancer
666
tumor
421
breast cancer
335
prostate cancer
326
neutropenia
261
lung cancer
167
non-small cell lung cancer
155
metastatic breast cancer
145
metastases
110
tumor growth
94
carcinoma
79
gastric cancer
71
adenocarcinoma
70
ovarian cancer
61
MCF
59
lung carcinoma
59
squamous cell carcinoma
51
myelosuppression
42
anemia
33
thrombocytopenia
29
leukopenia
29
peripheral neuropathy
29
melanoma
29
tumor progression
28
stomatitis
27
head and neck cancer
27
PSA
27
neuropathy
26
bone metastases
22
esophageal cancer
20
primary tumor
20
liver metastases
20
small cell lung cancer
20
esophageal cancer
19
leukemia
19
rash
17
Febrile neutropenia
17
measurable disease
16
epithelial ovarian cancer
16
onycholysis
16
more...
Symptom
diarrhea
56
fatigue
53
nausea
47
vomiting
46
asthenia
30
pain
28
anorexia
27
nausea and vomiting
13
erythema
11
myalgia
8
Ill
6
dyspnea
6
paresthesia
5
discomfort
4
constipation
4
weakness
4
discomfort
4
numbness
3
bone pain
3
cough
3
arthralgia
3
headache
3
abdominal pain
2
cachexia
2
decreased appetite
2
dysuria
2
seizures
2
exertional dyspnea
2
respiratory distress
2
epigastric pain
2
back pain
1
night sweats
1
chest tightness
1
Flare
1
bloating
1
leg pain
1
dry eye
1
acidity
1
onychophosis
1
hypothermia
1
more...
Drug
Docetaxel
1764
Taxotere
540
Taxol
119
Vinorelbine
36
Herceptin
27
Navelbine
26
GEO
24
CPT-11
23
Gemzar
23
G-CSF
22
Irinotecan
21
Pemetrexed
20
Adriamycin
18
Cremophor EL
16
CTX
15
Erlotinib
14
Bevacizumab
13
Xeloda
12
Dermatol
10
TTC
10
Alimta
10
vitamin E
9
CSF
9
Cetuximab
9
TAC
8
Filgrastim
8
Gefitinib
8
Indomethacin
8
Tarceva
7
Filgrastim
7
Vitamin E
7
EPI
7
Paraplatin
6
ADM
5
Zoledronic acid
5
Oxaliplatin
5
Epidoxorubicin
5
Zoledronic acid
5
ROS
4
Imatinib
4
more...
Enzyme
ERK
68
prostate-specific antigen
40
P-glycoprotein
32
mitogen-activated protein kinase
24
caspase-3
24
luciferase
17
CYP3A4
14
protein kinase
13
topoisomerase
10
topoisomerase
10
PARP
10
focal adhesion kinase
9
lactate dehydrogenase
8
DCF
8
alanine aminotransferase
7
glutathione peroxidase
7
thymidine phosphorylase
6
ACS
6
MDR
5
alkaline phosphatase
5
thymidylate synthase
4
AMPK
4
phosphodiesterase
4
AMP-activated protein kinase
4
caspase-9
4
AMPK
4
superoxide dismutase
4
proteasome
3
kinesin
3
thrombin
3
MEK
3
caspase-2
3
MTD
3
caspase-8
3
catalase
3
prostate-specific membrane antigen
3
NADPH oxidase
3
cdc2
3
protein kinase C
3
aspartate aminotransferase
3
more...
Compound
Docetaxel
1372
Dec
138
Clin
126
Paclitaxel
82
PEG
71
MDA
63
DNA
58
DDP
57
MTT
53
water
47
5-FU
43
PEG
36
Adriamycin
36
acetate
25
Gemcitabine
23
oxygen
23
Gemcitabine
23
CPT-11
22
Tween 80
21
ADR
21
CBDCA
17
CBDCA
17
ethanol
16
PLA
16
CTX
15
sodium
13
acetonitrile
12
phosphate
11
Androgen
11
iodine
10
bromide
10
Pluronic
9
Epirubicin
9
DOC
9
Capecitabine
9
GTP
8
Topotecan
8
Topotecan
8
calcium
8
retinoic acid
8
more...