Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D02165 (Docetaxel)
1,764 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 103
Mol 70
epidermal growth factor receptor 45
PC3 44
prostate-specific antigen 43
PC-3 42
HER2 39
granulocyte colony-stimulating factor 38
Bcl-2 33
P-glycoprotein 32
p53 31
caspase-3 31
androgen receptor 28
PSA 27
PEG 23
tyrosine kinase 23
G-CSF 23
albumin 18
bcl-2 17
PLA 16
NMR 16
TAG-1 15
annexin V 15
EGFR 15
PCL 14
CYP3A4 14
beta-tubulin 14
granulocyte 13
neu 13
C18 12
AKT 12
CD44 11
P-gp 11
cytochrome P450 11
JNK 11
MRI 11
vascular endothelial growth factor 11
p21 11
ABCB1 10
survivin 10
more...
Disease
cancer 666
tumor 421
breast cancer 335
prostate cancer 326
neutropenia 261
lung cancer 167
non-small cell lung cancer 155
metastatic breast cancer 145
metastases 110
tumor growth 94
carcinoma 79
gastric cancer 71
adenocarcinoma 70
ovarian cancer 61
MCF 59
lung carcinoma 59
squamous cell carcinoma 51
myelosuppression 42
anemia 33
thrombocytopenia 29
leukopenia 29
peripheral neuropathy 29
melanoma 29
tumor progression 28
stomatitis 27
head and neck cancer 27
PSA 27
neuropathy 26
bone metastases 22
esophageal cancer 20
primary tumor 20
liver metastases 20
small cell lung cancer 20
esophageal cancer 19
leukemia 19
rash 17
Febrile neutropenia 17
measurable disease 16
epithelial ovarian cancer 16
onycholysis 16
more...
Symptom
diarrhea 56
fatigue 53
nausea 47
vomiting 46
asthenia 30
pain 28
anorexia 27
nausea and vomiting 13
erythema 11
myalgia 8
Ill 6
dyspnea 6
paresthesia 5
discomfort 4
constipation 4
weakness 4
discomfort 4
numbness 3
bone pain 3
cough 3
arthralgia 3
headache 3
abdominal pain 2
cachexia 2
decreased appetite 2
dysuria 2
seizures 2
exertional dyspnea 2
respiratory distress 2
epigastric pain 2
back pain 1
night sweats 1
chest tightness 1
Flare 1
bloating 1
leg pain 1
dry eye 1
acidity 1
onychophosis 1
hypothermia 1
more...
Drug
Docetaxel 1764
Taxotere 540
Taxol 119
Vinorelbine 36
Herceptin 27
Navelbine 26
GEO 24
CPT-11 23
Gemzar 23
G-CSF 22
Irinotecan 21
Pemetrexed 20
Adriamycin 18
Cremophor EL 16
CTX 15
Erlotinib 14
Bevacizumab 13
Xeloda 12
Dermatol 10
TTC 10
Alimta 10
vitamin E 9
CSF 9
Cetuximab 9
TAC 8
Filgrastim 8
Gefitinib 8
Indomethacin 8
Tarceva 7
Filgrastim 7
Vitamin E 7
EPI 7
Paraplatin 6
ADM 5
Zoledronic acid 5
Oxaliplatin 5
Epidoxorubicin 5
Zoledronic acid 5
ROS 4
Imatinib 4
more...
Enzyme
ERK 68
prostate-specific antigen 40
P-glycoprotein 32
mitogen-activated protein kinase 24
caspase-3 24
luciferase 17
CYP3A4 14
protein kinase 13
topoisomerase 10
topoisomerase 10
PARP 10
focal adhesion kinase 9
lactate dehydrogenase 8
DCF 8
alanine aminotransferase 7
glutathione peroxidase 7
thymidine phosphorylase 6
ACS 6
MDR 5
alkaline phosphatase 5
thymidylate synthase 4
AMPK 4
phosphodiesterase 4
AMP-activated protein kinase 4
caspase-9 4
AMPK 4
superoxide dismutase 4
proteasome 3
kinesin 3
thrombin 3
MEK 3
caspase-2 3
MTD 3
caspase-8 3
catalase 3
prostate-specific membrane antigen 3
NADPH oxidase 3
cdc2 3
protein kinase C 3
aspartate aminotransferase 3
more...
Compound
Docetaxel 1372
Dec 138
Clin 126
Paclitaxel 82
PEG 71
MDA 63
DNA 58
DDP 57
MTT 53
water 47
5-FU 43
PEG 36
Adriamycin 36
acetate 25
Gemcitabine 23
oxygen 23
Gemcitabine 23
CPT-11 22
Tween 80 21
ADR 21
CBDCA 17
CBDCA 17
ethanol 16
PLA 16
CTX 15
sodium 13
acetonitrile 12
phosphate 11
Androgen 11
iodine 10
bromide 10
Pluronic 9
Epirubicin 9
DOC 9
Capecitabine 9
GTP 8
Topotecan 8
Topotecan 8
calcium 8
retinoic acid 8
more...