Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D02027 (Tranilast)
 205 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
collagen 23
mast cell 16
platelet-derived growth factor 12
TGF-beta 10
transforming growth factor-beta 9
Mol 9
Sep 8
cytokine 8
p21 8
tumor necrosis factor 6
IgE 6
insulin 5
interferon-gamma 5
lipopolysaccharide 4
serum albumin 4
cyclooxygenase 4
beta 1 4
IL-1 3
MHC 3
p53 3
ERK1 3
cyclin D1 3
IL-6 3
lactate dehydrogenase 3
lacrimal 3
lymphoid 3
TRPV2 3
cyclin-dependent kinase 3
fibronectin 3
heme oxygenase-1 3
cyclin 3
MMP-9 3
SRS 3
interleukin-2 3
vascular endothelial growth factor 3
Smad2 3
CSD 3
myeloperoxidase 2
metalloproteinase 2
chemokine 2
aryl hydrocarbon receptor 2
IL-13 2
IL-10 2
glucuronosyltransferase 2
c-myc 2
ALK-5 2
substance P 2
cyclooxygenase-2 2
PARP 2
CDK2 2
caspase-8 2
monocyte chemoattractant protein 2
COL3A1 2
angiotensin II 2
SOD 2
matrix metalloproteinase 2
TNF 2
LDH 2
cyclin-dependent kinase 2 2
alkaline phosphatase 2
IL-2 2
PDGF 2
TRPV4 2
albumin 2
TGF-beta3 2
IL-1 beta 2
phosphatidylinositol 3-kinase 2
follicle-stimulating hormone 2
insulin-like growth factor 2
TGF-beta type II receptor 2
inducible nitric oxide synthase 2
eosinophil peroxidase 2
IL-5 2
thrombin 2
phosphodiesterase 2
stem cell factor 2
ACS 2
AMP 2
NMR 1
platelet-derived growth factor-BB 1
OAT3 1
indoleamine 2,3-dioxygenase 1
ADP 1
fibronectin mRNA 1
lymphokine 1
ATPase 1
IL-33 1
BLM 1
CTLA-4 1
PAF 1
ICAM-1 1
HOS 1
cage 1
interleukin 6 1
HLA class II 1
nitric oxide synthase 1
MMP-7 1
ATP 1
hairless 1
ATP7B 1
neurofibromin 1
UTR 1
ABCG2 1
GLUT9 1
transforming growth factor beta 1 1
amphiregulin 1
NPT1 1
IL-17 1
Axin2 1
cyclin-dependent kinase inhibitor 1
Cytokine 1
OAT1 1
CXCL9 1
cyclooxygenase 2 1
MAPK 1
p27 1
She 1
histamine H1 receptor 1
ATOX1 1
vascular cell adhesion molecule-1 1
DBA 1
TRP 1
Hua 1
rat) 1
ROS 1
MAP 1
class II antigen 1
PD-1 1
NMDA receptor 1
TGF-beta2 1
UGT1A1 1
signal transducer and activator of transcription 1 1
EDS1 1
Wilson disease 1
CD34 1
ALK2 1
VRL-1 1
mitogen-activated protein 1
low-density lipoprotein receptor 1
AIT 1
CD18 1
microsomal 1
HO-1 1
lysyl hydroxylase 1
NF1 1
EBP 1
CD38 1
apolipoprotein E 1
HLA-DR 1
transcriptional coactivator 1
endothelial nitric oxide synthase 1
pyrin 1
thioredoxin 1
JNK 1
RST 1
HLA-DQ 1
proliferating cell nuclear antigen 1
B protein 1
CXCL12 protein 1
Indoleamine 2,3-dioxygenase 1
more...
Disease
asthma 25
tumor 16
cancer 11
cystitis 8
anaphylaxis 7
atherosclerosis 7
breast cancer 7
atopic dermatitis 7
diabetes 5
pruritus 4
myocardial infarction 4
tumor growth 4
allergic rhinitis 4
allergic conjunctivitis 3
rheumatoid arthritis 3
diabetic nephropathy 3
SRS 3
MCF 3
ischemia 3
retinoblastoma 2
arthritis 2
lung cancer 2
hay fever 2
pyuria 2
Alzheimer's disease 2
Larynx 2
Larynx 2
carcinoma 2
Larynx 2
conjunctiva 2
metastases 2
arteriosclerosis 2
urticaria 2
skin disease 2
hypertension 2
leiomyoma 2
neurofibroma 2
hyperbilirubinemia 2
eosinophilia 2
otitis media 2
tumor progression 2
sarcoidosis 2
Larynx 2
scleroderma 2
heart failure 2
Vesicoureteral reflux 1
cornea 1
tumor angiogenesis 1
glomerulonephritis 1
Bladder 1
primary tumor 1
sarcoma 1
progeria 1
Osteosarcoma 1
muscular dystrophy 1
proteinuria 1
Schistosoma mansoni 1
diabetic retinopathy 1
gastric cancer 1
Evans 1
renal disease 1
Bladder 1
obesity 1
colorectal cancer 1
violence 1
Nystagmus 1
glomerulosclerosis 1
lung carcinoma 1
multiple sclerosis 1
Osteosarcoma 1
LTD 1
Eosinophilic cystitis 1
Conjunctiva 1
coronary heart disease 1
diabetic cardiomyopathy 1
localized scleroderma 1
insulinoma 1
macular degeneration 1
genetic disorder 1
EMA 1
chronic pain 1
PAF 1
endolymphatic hydrops 1
vulvitis 1
nasal allergy 1
Sarcoma 1
facial palsy 1
Sarcoma 1
premature aging 1
blepharitis 1
proliferative diabetic retinopathy 1
tumor initiation 1
HOS 1
prurigo 1
gout 1
stroke 1
Gilbert 1
aqueous humor 1
Rosenthal 1
cardiomyopathy 1
graft-versus-host disease 1
colitis 1
pulmonary fibrosis 1
BLM 1
leukemia 1
thrombocytopenia 1
ATM 1
ulcerative colitis 1
cheilitis 1
uterine leiomyoma 1
Renal interstitial fibrosis 1
ventricular hypertrophy 1
polymyositis 1
Syndrome 1
Bladder 1
Chlamydia 1
Glioblastoma 1
morphea 1
hepatic encephalopathy 1
osteoporosis 1
DBA 1
Adhesion 1
amyotrophic lateral sclerosis 1
uricosuria 1
nystagmus 1
epithelial ovarian cancer 1
hyperuricemia 1
neurofibromatosis type 1 1
glaucoma 1
INS 1
herpes 1
ovarian cancer 1
osteosarcoma 1
dermatitis 1
glioblastoma 1
dysphagia 1
FBS 1
liver fibrosis 1
mastocytoma 1
degenerative disease 1
Chronic GVHD 1
GSH 1
male infertility 1
hypercholesterolemia 1
adenocarcinoma 1
psoriasis 1
middle ear effusion 1
Conjunctiva 1
bacterial infection 1
type 2 diabetes 1
glioma 1
vasculitis 1
petechiae 1
inflammatory bowel disease 1
rhinitis 1
Symptom
pain 5
sneezing 2
erythema 1
dry eye 1
nasal congestion 1
sleepiness 1
cough 1
dyspnea 1
skin damage 1
Drug
Tranilast 205
Dermatol 10
Clofibrate 3
Ketotifen 3
Cinnarizine 3
Patanol 2
Cardiovasc 2
Zepelin 2
IL-2 2
Livostin 2
Levocabastine 2
Olopatadine hydrochloride 2
Zaditen 1
Carbopol 934 1
nitroglycerin 1
ROS 1
Histamine 1
niacin 1
Asthma 1
ADM 1
BLM 1
Intal 1
Angiotensin II 1
Pemirolast 1
Gel 1
Rolipram 1
Indomethacin 1
Methylprednisolone 1
Ozagrel 1
MAP 1
Rutin 1
Adriamycin 1
Ibudilast 1
Enzyme
mitogen-activated protein kinase 8
protein kinase 4
lactate dehydrogenase 3
reverse transcriptase 3
phosphodiesterase 2
thrombin 2
alkaline phosphatase 2
UDP-glucuronosyltransferase 2
PARP 2
hexosaminidase 2
peroxidase 2
luciferase 2
phosphatidylinositol 3-kinase 2
ACS 2
collagenase 1
firefly luciferase 1
prolyl hydroxylase 1
MAP 1
NO synthase 1
alanine aminotransferase 1
protein kinase C 1
phospholipase A2 1
aspartate aminotransferase 1
EC 5.3.99.2 1
indoleamine 2,3-dioxygenase 1
caspase-8 1
guanylate cyclase 1
heme oxygenase 1
PDO 1
phospholipase C 1
BMT 1
MMP 1
trypsin 1
tryptase 1
creatine kinase 1
lysyl hydroxylase 1
xanthine oxidase 1
ACE 1
superoxide dismutase 1
elastase 1
aequorin 1
ATPase 1
Compound
Dec 17
calcium 12
DNA 11
tryptophan 7
nitric oxide 7
Clin 7
tryptophan 6
tryptophan 6
tryptophan 6
water 5
sodium 5
glucose 5
urea 4
creatinine 4
MDA 4
silver 3
potassium 3
MTT 3
Cardiol 3
C18H17NO5 2
sulfate 2
salt 2
C18H17NO5 2
C18H17NO5 2
Nifedipine 2
ACS 2
ACS 2
C18H17NO5 2
C16H14N2O2 2
C18H17NO5 2
C18H17NO5 2
Disodium cromoglycate 2
C18H17NO5 2
PGE 2
Collagen 2
Azelastine 2
C18H17NO5 2
hydroxycinnamic acid 2
C18H17NO5 2
C18H17NO5 2
C18H17NO5 2
PGE2 2
C18H17NO5 2
C18H17NO5 2
AMP 2
Triamcinolone 2
TNF 2
tyrosine 2
C18H17NO5 2
PGH2 1
palmitic acid 1
C15H10FNO2 1
C15H10FNO2 1
Telmisartan 1
BLM 1
Verapamil 1
Piroxicam 1
ammonia 1
TAA 1
arginine 1
ADP 1
Angiotensin II 1
Hearts 1
C15H10FNO2 1
LTE4 1
proline 1
FMLP 1
uridine 1
Methotrexate 1
H2O2 1
UDP 1
Methylprednisolone 1
MAP 1
BCG 1
Metyrapone 1
Tetrahydrobiopterin 1
cGMP 1
Amphotericin B 1
Iodo 1
copper 1
C15H10FNO2 1
zinc 1
ATP 1
Isoproterenol 1
leucine 1
GSH 1
iron 1
Neuronal 1
Metyrapone 1
p-cresol 1
p-cresol 1
Dexamethasone 1
oxygen 1
Rose Bengal 1
LTC4 1
Insulin 1
Uric acid 1
3-hydroxyanthranilic acid 1
prostacyclin 1
Metformin 1
cAMP 1
TGR 1
nitrogen 1
iodine 1
Cyproterone acetate 1
hydrogen 1
DBA 1
bromide 1
C15H10FNO2 1
DPPH 1
Verapamil 1
Interleukin-2 1
DDP 1
Aminophylline 1
COS 1
Riluzole 1
SOA 1
Cinnamic acid 1
Pentoxifylline 1
C15H10FNO2 1
ethanol 1
Methacholine 1
DNP 1
palmitic acid 1
MEE 1
SP-1 1
NiCl2 1
Diabetol 1
ADP 1
acetate 1
Substance P 1
noradrenaline 1
tin 1
C15H10FNO2 1
Theophylline 1
hydroxide 1
ADP 1
Isatin 1
Histamine 1
DBA 1
Indomethacin 1
L-carnitine 1
DBA 1
adenylate 1
8-OHdG 1
GSH 1
aluminum 1
Hearts 1
benzene 1
serine 1
Metformin 1
LTD 1
Rutin 1
A 3 1
acridine 1