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 1,323 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The aim of this study was to assess the in vitro potential of ethanolic extract of Caesalpinia bonducella seeds as a natural antioxidant. The DPPH activity of the extract (20, 40, 50, 100 and 200 microg/ml) was increased in a dose dependent manner, which was found in the range of 38.93-74.77% as compared to ascorbic acid (64.26-82.58%). The IC(50) values of ethanolic extract and ascorbic acid in DPPH radical scavenging assay were obtained to be 74.73 and 26.68 microg/ml, respectively. The ethanolic extract was also found to scavenge the superoxide generated by EDTA/NBT system. Measurement of total phenolic content of the ethanolic extract of C. bonducella was achieved using Folin-Ciocalteau reagent containing 62.50mg/g of phenolic content, which was found significantly higher when compared to reference standard gallic acid. The ethanolic extract also inhibited the hydroxyl radical, nitric oxide, superoxide anions with IC(50) values of 109.85, 102.65 and 89.84 microg/ml, respectively. However, the IC(50) values for the standard ascorbic acid were noted to be 70.79, 65.98 and 36.68 microg/ml respectively. The results obtained in this study clearly indicate that C. bonducella has a significant potential to use as a natural antioxidant agent.
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PMID:Antioxidant activity and total phenolic content of ethanolic extract of Caesalpinia bonducella seeds. 1942 71

The aim of this study was to assess the in vitro potential of ethanolic leaf extract of Stevia rebaudiana as a natural antioxidant. The DPPH activity of the extract (20, 40, 50, 100 and 200 microg/ml) was increased in a dose dependent manner, which was found in the range of 36.93-68.76% as compared to ascorbic acid 64.26-82.58%. The IC(50) values of ethanolic extract and ascorbic acid in DPPH radical scavenging assay were obtained to be 93.46 and 26.75 microg/ml, respectively. The ethanolic extract was also found to scavenge the superoxide generated by EDTA/NBT system. Measurement of total phenolic content of the ethanolic extract of S. rebaudiana was achieved using Folin-Ciocalteau reagent containing 61.50 mg/g of phenolic content, which was found significantly higher when compared to reference standard gallic acid. The ethanolic extract also inhibited the hydroxyl radical, nitric oxide, superoxide anions with IC(50) values of 93.46, 132.05 and 81.08 microg/ml, respectively. However, the IC(50) values for the standard ascorbic acid were noted to be 26.75, 66.01 and 71.41 microg/ml respectively. The results obtained in this study clearly indicate that S. rebaudiana has a significant potential to use as a natural antioxidant agent.
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PMID:In vitro antioxidant activity and total phenolic content of ethanolic leaf extract of Stevia rebaudiana Bert. 1954 Sep