Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D01968 (
Zoledronic acid
)
505
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
41
Mol
21
alkaline phosphatase
17
RANKL
13
type I collagen
12
insulin
11
aromatase
11
osteosarcoma
9
cytokine
9
osteocalcin
9
RANK
8
collagen
8
caspase-3
8
BMD
8
CTX
7
MRI
7
She
7
osteoprotegerin
6
parathyroid hormone
6
LHRH
6
more...
Disease
cancer
164
bone metastases
138
osteoporosis
121
breast cancer
101
prostate cancer
91
tumor
85
multiple myeloma
69
bone disease
60
metastases
45
hypercalcemia
42
lung cancer
33
hypercalcemia of malignancy
24
spinal cord compression
23
tumor growth
23
PDB
16
metastatic breast cancer
13
renal cell carcinoma
13
influenza
11
carcinoma
11
osteosarcoma
10
more...
Symptom
pain
53
bone pain
47
nausea
6
fatigue
5
arthralgia
4
vomiting
4
myalgia
4
weakness
2
anesthesia
2
headache
2
constipation
2
back pain
2
diarrhea
2
chills
1
halitosis
1
anorexia
1
functional recovery
1
acute pain
1
dyspnea
1
photophobia
1
more...
Drug
Zoledronic acid
505
Zoledronic acid
505
Denosumab
22
APD
17
Aredia
17
Bevacizumab
11
Gleevec
10
Pegasys
9
CTX
9
Gefitinib
8
Cetuximab
7
Rosuvastatin calcium
7
Bortezomib
7
Sorafenib
7
Teriparatide
7
CTX
7
Fondaparinux
7
G-CSF
7
Adalimumab
7
CTX
7
more...
Enzyme
alkaline phosphatase
17
mitogen-activated protein kinase
7
caspase-3
6
FAST
4
ERK
4
GSK
4
luciferase
3
focal adhesion kinase
3
protein kinase
3
prostate-specific antigen
3
cathepsin K
3
alanine aminotransferase
3
ACE
2
PARP
2
urokinase-type plasminogen activator
2
gamma-glutamyl transpeptidase
2
aspartate aminotransferase
2
MEK
2
farnesyltransferase
2
acid phosphatase
2
more...
Compound
Clin
69
nitrogen
59
calcium
54
Dec
33
creatinine
18
vitamin D
17
sodium
17
Alendronate
14
acetate
13
Pamidronate
13
MDA
12
PEG
11
salt
11
CTX
9
Alendronate
8
BMD
8
phosphate
8
Aripiprazole
7
Androgen
7
bromide
7
more...