Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D01849 (
Cardiovasc
)
199,335
document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
10356
Gen
2271
renin
1291
insulin
1030
angiotensin II
1009
collagen
788
She
766
endothelin-1
736
calcium channel
591
ATP
575
MRI
529
Ang II
487
thrombin
484
nitric oxide synthase
432
creatine kinase
375
nodal
367
ET-1
336
bradykinin
324
natriuretic peptide
305
ACE
301
phosphodiesterase
296
hemoglobin
296
Mal
285
C-reactive protein
282
cytokine
272
HDL
267
PCI
267
fibrinogen
265
beta 1
265
superoxide dismutase
263
ETA
262
angiotensin receptor
245
cardiac muscle
237
vasopressin
225
albumin
219
cyclooxygenase
218
lactate dehydrogenase
216
ETB
211
tumor necrosis factor
209
ADP
207
more...
Disease
heart failure
5111
hypertension
4808
myocardial infarction
4311
ischemia
3731
stroke
3244
coronary artery disease
3137
atherosclerosis
2712
cardiovascular disease
2666
tumor
2538
diabetes
2249
myocardial ischemia
2063
heart disease
1818
acute myocardial infarction
1623
congestive heart failure
1597
cancer
1489
plaque
1436
aortic stenosis
1224
cardiomyopathy
1214
mitral regurgitation
1108
endocarditis
1054
ventricular septal defect
944
obesity
921
pulmonary hypertension
893
aortic regurgitation
891
lung cancer
875
ventricular fibrillation
810
coronary heart disease
763
depression
748
essential hypertension
711
ventricular hypertrophy
643
aortic aneurysm
625
atrial septal defect
613
type 2 diabetes
582
vascular disease
562
unstable angina
540
abdominal aortic aneurysm
539
metastases
530
cold
502
dilated cardiomyopathy
497
pulmonary embolism
489
more...
Symptom
angina
1654
chest pain
1009
regurgitation
937
pain
901
dyspnea
822
anesthesia
711
hypothermia
705
syncope
366
spasm
313
hemoptysis
311
cough
298
functional recovery
276
fatigue
266
collapse
228
discomfort
193
cyanosis
193
discomfort
191
headache
189
respiratory distress
181
shortness of breath
176
overweight
165
abdominal pain
149
back pain
138
dizziness
135
weakness
126
exertional dyspnea
125
flushing
100
thinning
95
analgesia
90
nausea
79
vomiting
73
seizures
65
diarrhea
52
atypical chest pain
49
exertional angina
47
hypercapnia
45
hoarseness
44
sleepiness
39
paraparesis
39
hemiplegia
35
more...
Drug
Cardiovasc
199335
nitroglycerin
447
ETA
255
Angiotensin II
146
caffeine
93
Captopril
86
Clopidogrel
86
ROC
81
ICI
81
MAP
80
vitamin E
79
Indomethacin
71
Nephron
70
niacin
68
Levosimendan
62
ascorbate
52
Clonidine
51
lysine
49
APD
48
Ranolazine
48
Ranolazine
48
CTA
48
Felodipine
46
Atenolol
45
Ouabain
40
ROS
39
Nebivolol
39
Abciximab
39
CaCl2
39
Adenosine triphosphate
38
Ramipril
38
CaCl2
35
CaCl2
35
Valsartan
34
Aprotinin
34
Lipiodol
33
Isradipine
33
Gelfoam
32
NADH
32
Simvastatin
31
more...
Enzyme
renin
1291
ACE
553
creatine kinase
525
thrombin
467
phosphodiesterase
296
superoxide dismutase
292
lactate dehydrogenase
240
ATPase
237
protein kinase
235
protein kinase C
231
thromboplastin
221
mitogen-activated protein kinase
212
NO synthase
209
tissue plasminogen activator
187
catalase
172
urokinase-type plasminogen activator
162
guanylate cyclase
157
adenylate cyclase
135
ERK
130
CAD
118
CAD
118
CAD
118
CD10
109
peroxidase
99
NADPH oxidase
98
caspase-3
97
xanthine oxidase
88
endothelin-converting enzyme
85
glutathione peroxidase
73
plasmin
72
MAP
72
APC
69
proteasome
67
NOS
66
kallikrein
65
phospholipase C
62
NADPH oxidase
62
aspartate aminotransferase
60
ACS
60
phospholipase A2
55
more...
Compound
Dec
13559
calcium
3481
BMC
2658
oxygen
2395
Clin
1973
Diabetol
1944
Diabetol
1941
sodium
1864
nitric oxide
1372
potassium
1168
glucose
1161
water
825
arginine
667
aldosterone
625
ATP
576
DNA
504
acetate
484
creatinine
471
salt
470
His
440
phosphate
440
noradrenaline
437
prostacyclin
422
ADP
357
CO2
336
cGMP
267
PCI
263
Ang II
255
ETA
255
Angiotensin II
242
nitrate
232
Hearts
216
Hearts
214
ADP
212
ADP
207
AMP
204
ASA
174
ethanol
172
cAMP
169
iron
168
more...