Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D01398 (
Dermatol
)
262,401
document(s) hit in 31,850,051 MEDLINE articles (0.07 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
15821
JAMA
3011
collagen
2651
cytokine
1608
She
1145
keratin
1068
tumor necrosis factor
873
IgE
829
CD4
697
IgA
694
interferon
615
hairless
593
tyrosinase
552
lymphoid
523
mast cell
520
CD8
517
TNF
499
HLA
490
p53
450
IL-17
432
HLA-DR
427
IL-6
417
fibronectin
415
IFN
410
IL-4
387
filaggrin
387
insulin
381
IL-8
380
interferon-gamma
357
K10
348
involucrin
343
BRAF
308
IFN-gamma
303
TNF-alpha
295
IL-10
291
type VII collagen
281
IL-1
275
epidermal growth factor
271
ICAM-1
270
mucin
267
chemokine
267
elastin
266
polypeptide
250
IL-23
249
BP180
249
calcineurin
236
collagenase
235
glycoprotein
231
IL-2
224
CD1a
224
vascular endothelial growth factor
223
substance P
222
K14
216
CO2
214
all-trans
213
X-linked
205
endoplasmic reticulum
203
neurofibromatosis
203
p38
202
epidermal growth factor receptor
195
S100
192
nodal
186
matrix metalloproteinase
180
major histocompatibility complex
180
type I collagen
178
loricrin
178
vimentin
178
CD20
177
CD34
175
scratch
175
beta-endorphin
174
tyrosine kinase
173
peroxidase
171
tumor necrosis factor alpha
171
AMP
170
transglutaminase
169
cytokeratin
165
adhesion molecule
165
CD30
163
Ki-67
162
more...
Disease
psoriasis
7084
tumor
5209
melanoma
4662
cancer
4195
skin disease
4007
atopic dermatitis
3318
dermatitis
2544
pruritus
2251
acne
2172
mole
2108
skin cancer
2095
plaque
2061
squamous cell carcinoma
1824
basal cell carcinoma
1433
Contact Dermatitis
1429
pemphigoid
1421
pemphigus
1415
vitiligo
1321
lupus
1260
systemic lupus erythematosus
1248
mole
1238
epidermolysis bullosa
1161
eczema
1133
carcinoma
1095
vasculitis
1078
metastases
1074
acne vulgaris
1059
rash
1051
mycosis fungoides
1042
urticaria
1020
lichen planus
1015
HIV
1007
lymphoma
964
hyperkeratosis
940
alopecia areata
861
warts
824
diabetes
805
lupus
794
ichthyosis
788
PSS
758
keratosis
748
cutaneous T-cell lymphoma
739
ichthyosis
733
erythroderma
687
immunodeficiency
677
scleroderma
638
rosacea
628
autoimmune disease
597
leprosy
584
photosensitivity
578
fungal infection
559
psoriatic arthritis
537
pyoderma gangrenosum
533
sarcoidosis
528
herpes simplex
513
onychomycosis
498
rheumatoid arthritis
494
carcinogenesis
484
AIDS
478
eosinophilia
478
lymphadenopathy
476
systemic disease
474
tuberculosis
473
arthritis
467
infectious diseases
467
hemangioma
466
dermatomyositis
462
depression
456
Kaposi's sarcoma
439
purpura
430
Mycobacterium
426
leukemia
415
panniculitis
415
folliculitis
412
seborrheic dermatitis
411
syphilis
390
erythema multiforme
381
cutaneous melanoma
381
Bowen's disease
378
lichen
374
more...
Symptom
erythema
2782
pain
1498
anesthesia
339
discomfort
315
discomfort
309
diarrhea
231
arthralgia
197
thinning
197
Welt
186
dry skin
185
headache
177
livedo
173
weakness
168
skin damage
165
skin irritation
152
flushing
148
tense
147
nausea
127
Ill
124
fatigue
120
seizures
106
pachyonychia
103
vomiting
103
hepatosplenomegaly
98
abdominal pain
81
dyspnea
76
myalgia
68
anorexia
62
photophobia
57
collapse
56
excessive sweating
54
hoarseness
54
paresthesia
53
hepatomegaly
52
pallor
51
cough
50
stigma
48
respiratory distress
48
overweight
47
splenomegaly
44
numbness
44
analgesia
43
chills
43
tingling
40
scaly skin
37
clubbing
35
back pain
34
onychomadesis
33
sleepiness
32
unwanted hair
30
adenitis
30
cyanosis
29
hypothermia
28
Darier's sign
28
physical appearance
27
generalized erythema
27
exhaustion
27
starvation
27
dizziness
25
asthenia
25
lethargy
23
brittle nails
23
constipation
23
neuralgia
23
insomnia
22
paresis
22
Livedoid
22
ataxia
22
dysesthesia
21
nausea and vomiting
20
Beau's lines
19
periorbital edema
19
sore throat
18
koilonychia
18
acidity
17
spasticity
17
agitation
16
dry eye
16
generalized rash
16
syncope
16
more...
Drug
Dermatol
262401
IFN-gamma
290
Retinoic acid
265
IL-2
228
Imiquimod
148
Isotretinoin
141
CSF
140
vitamin E
113
lysine
103
ascorbate
96
Histamine
92
Rituximab
88
Tacrolimus
80
Infliximab
72
Infliximab
72
Itraconazole
68
Retinoic Acid
64
Adalimumab
59
Acitretin
58
ALA
58
Clobetasol propionate
55
Dithranol
55
ampicillin
54
Triclosan
53
CAM
52
Vitamin A
51
ROS
48
Calcipotriol
48
caffeine
47
Adapalene
42
Omalizumab
42
niacin
42
Indomethacin
39
Ketoconazole
39
p75
38
Gel
38
Allergen
37
MAP
33
Efalizumab
32
Efalizumab
32
Pimecrolimus
32
ABC
31
Acyclovir
31
CTX
30
Leaf
29
Finasteride
28
Diphenhydramine
27
Alefacept
26
Fluconazole
25
Bexarotene
23
Doxycycline
23
EE2
23
L-tyrosine
22
Ipilimumab
22
Lamisil
22
Lamisil
22
NADH
22
Prednisolone
21
Botox
21
ENT
20
nitroglycerin
19
KGF
19
Sorafenib
19
Glutathione
19
Paraffin
18
CPO
18
Imatinib
18
citric acid
18
Gleevec
18
ICI
17
CaCl2
17
IFN-beta
17
CaCl2
17
CaCl2
17
lactose
17
PDL
17
Asthma
16
Aloe
16
G-CSF
16
Prednisone
15
more...
Enzyme
mitogen-activated protein kinase
541
tyrosinase
537
ERK
449
collagenase
368
trypsin
327
peroxidase
265
reverse transcriptase
253
calcineurin
242
protein kinase C
213
transglutaminase
199
protein kinase
185
catalase
168
ATPase
155
superoxide dismutase
152
phosphodiesterase
152
focal adhesion kinase
151
MEK
141
tryptase
129
alkaline phosphatase
127
adenylate cyclase
110
caspase-3
104
lactate dehydrogenase
103
plasmin
101
DCF
101
luciferase
100
urokinase-type plasminogen activator
93
elastase
92
hyaluronidase
85
ornithine decarboxylase
82
lysozyme
81
hyaluronidase
71
lipoxygenase
69
RNA polymerase
65
beta-galactosidase
64
phospholipase C
63
acid phosphatase
63
glutathione peroxidase
61
endonuclease
60
APC
60
MMP-3
59
lipase
59
phospholipase A2
58
chymase
57
CD10
54
RNase
54
RNase
54
kallikrein
52
transcriptase
50
granzyme B
47
caspase-1
46
neutrophil elastase
45
ACE
44
type III procollagen
42
interstitial collagenase
42
thrombin
41
KLK7
41
alanine aminotransferase
41
proteasome
40
neuraminidase
39
matrix metalloproteinase 2
39
beta-glucuronidase
38
DNA polymerase
37
pepsin
37
matrix metalloproteinase 9
35
glucose-6-phosphate dehydrogenase
34
glutathione S-transferase
34
cathepsin D
34
uroporphyrinogen decarboxylase
34
chymotrypsin
33
aspartate aminotransferase
33
xanthine oxidase
32
arylsulfatase
32
ferrochelatase
32
MMP
31
tissue plasminogen activator
30
gamma-glutamyl transpeptidase
29
phosphatidylinositol 3-kinase
29
botulinum neurotoxin
28
glutathione reductase
27
papain
27
more...
Compound
Dec
17342
Clin
17167
DNA
3312
water
1492
calcium
1231
sodium
815
oxygen
764
retinoic acid
692
sulfate
574
acetate
570
TNF
499
zinc
462
His
454
vitamin D
397
CO2
397
hyaluronic acid
361
phosphate
360
potassium
328
nickel
307
tyrosine
286
BMC
271
glucose
271
salt
238
nitrogen
230
serine
227
iodine
225
silver
220
iron
214
urea
205
salicylic acid
205
leucine
203
arginine
203
ethanol
196
hydrogen
182
cAMP
177
AMP
177
SDS
170
Collagen
169
cysteine
168
pyrimidine
165
pyrimidine
164
retinol
162
nitric oxide
160
hydroquinone
153
acetone
149
Cyclosporine
141
copper
140
aluminum
137
galactose
130
hydroxide
126
lysine
122
Methotrexate
122
KOH
122
azelaic acid
122
methionine
121
MOP
119
DSS
113
proline
111
nicotinamide
108
Phe
108
MEK
106
phenol
106
formaldehyde
105
Etretinate
105
ATP
103
FK506
101
PGE2
100
creatinine
99
Keratin
98
tryptophan
95
TCA
94
Histamine
92
H2O2
89
propylene glycol
89
bromide
86
EDTA
85
glycerol
85
EDTA
85
SCC
85
formaldehyde
84
more...