Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D01398 (Dermatol)
262,401 document(s) hit in 31,850,051 MEDLINE articles (0.07 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 15821
JAMA 3011
collagen 2651
cytokine 1608
She 1145
keratin 1068
tumor necrosis factor 873
IgE 829
CD4 697
IgA 694
interferon 615
hairless 593
tyrosinase 552
lymphoid 523
mast cell 520
CD8 517
TNF 499
HLA 490
p53 450
IL-17 432
HLA-DR 427
IL-6 417
fibronectin 415
IFN 410
IL-4 387
filaggrin 387
insulin 381
IL-8 380
interferon-gamma 357
K10 348
involucrin 343
BRAF 308
IFN-gamma 303
TNF-alpha 295
IL-10 291
type VII collagen 281
IL-1 275
epidermal growth factor 271
ICAM-1 270
mucin 267
chemokine 267
elastin 266
polypeptide 250
IL-23 249
BP180 249
calcineurin 236
collagenase 235
glycoprotein 231
IL-2 224
CD1a 224
vascular endothelial growth factor 223
substance P 222
K14 216
CO2 214
all-trans 213
X-linked 205
endoplasmic reticulum 203
neurofibromatosis 203
p38 202
epidermal growth factor receptor 195
S100 192
nodal 186
matrix metalloproteinase 180
major histocompatibility complex 180
type I collagen 178
loricrin 178
vimentin 178
CD20 177
CD34 175
scratch 175
beta-endorphin 174
tyrosine kinase 173
peroxidase 171
tumor necrosis factor alpha 171
AMP 170
transglutaminase 169
cytokeratin 165
adhesion molecule 165
CD30 163
Ki-67 162
more...
Disease
psoriasis 7084
tumor 5209
melanoma 4662
cancer 4195
skin disease 4007
atopic dermatitis 3318
dermatitis 2544
pruritus 2251
acne 2172
mole 2108
skin cancer 2095
plaque 2061
squamous cell carcinoma 1824
basal cell carcinoma 1433
Contact Dermatitis 1429
pemphigoid 1421
pemphigus 1415
vitiligo 1321
lupus 1260
systemic lupus erythematosus 1248
mole 1238
epidermolysis bullosa 1161
eczema 1133
carcinoma 1095
vasculitis 1078
metastases 1074
acne vulgaris 1059
rash 1051
mycosis fungoides 1042
urticaria 1020
lichen planus 1015
HIV 1007
lymphoma 964
hyperkeratosis 940
alopecia areata 861
warts 824
diabetes 805
lupus 794
ichthyosis 788
PSS 758
keratosis 748
cutaneous T-cell lymphoma 739
ichthyosis 733
erythroderma 687
immunodeficiency 677
scleroderma 638
rosacea 628
autoimmune disease 597
leprosy 584
photosensitivity 578
fungal infection 559
psoriatic arthritis 537
pyoderma gangrenosum 533
sarcoidosis 528
herpes simplex 513
onychomycosis 498
rheumatoid arthritis 494
carcinogenesis 484
AIDS 478
eosinophilia 478
lymphadenopathy 476
systemic disease 474
tuberculosis 473
arthritis 467
infectious diseases 467
hemangioma 466
dermatomyositis 462
depression 456
Kaposi's sarcoma 439
purpura 430
Mycobacterium 426
leukemia 415
panniculitis 415
folliculitis 412
seborrheic dermatitis 411
syphilis 390
erythema multiforme 381
cutaneous melanoma 381
Bowen's disease 378
lichen 374
more...
Symptom
erythema 2782
pain 1498
anesthesia 339
discomfort 315
discomfort 309
diarrhea 231
arthralgia 197
thinning 197
Welt 186
dry skin 185
headache 177
livedo 173
weakness 168
skin damage 165
skin irritation 152
flushing 148
tense 147
nausea 127
Ill 124
fatigue 120
seizures 106
pachyonychia 103
vomiting 103
hepatosplenomegaly 98
abdominal pain 81
dyspnea 76
myalgia 68
anorexia 62
photophobia 57
collapse 56
excessive sweating 54
hoarseness 54
paresthesia 53
hepatomegaly 52
pallor 51
cough 50
stigma 48
respiratory distress 48
overweight 47
splenomegaly 44
numbness 44
analgesia 43
chills 43
tingling 40
scaly skin 37
clubbing 35
back pain 34
onychomadesis 33
sleepiness 32
unwanted hair 30
adenitis 30
cyanosis 29
hypothermia 28
Darier's sign 28
physical appearance 27
generalized erythema 27
exhaustion 27
starvation 27
dizziness 25
asthenia 25
lethargy 23
brittle nails 23
constipation 23
neuralgia 23
insomnia 22
paresis 22
Livedoid 22
ataxia 22
dysesthesia 21
nausea and vomiting 20
Beau's lines 19
periorbital edema 19
sore throat 18
koilonychia 18
acidity 17
spasticity 17
agitation 16
dry eye 16
generalized rash 16
syncope 16
more...
Drug
Dermatol 262401
IFN-gamma 290
Retinoic acid 265
IL-2 228
Imiquimod 148
Isotretinoin 141
CSF 140
vitamin E 113
lysine 103
ascorbate 96
Histamine 92
Rituximab 88
Tacrolimus 80
Infliximab 72
Infliximab 72
Itraconazole 68
Retinoic Acid 64
Adalimumab 59
Acitretin 58
ALA 58
Clobetasol propionate 55
Dithranol 55
ampicillin 54
Triclosan 53
CAM 52
Vitamin A 51
ROS 48
Calcipotriol 48
caffeine 47
Adapalene 42
Omalizumab 42
niacin 42
Indomethacin 39
Ketoconazole 39
p75 38
Gel 38
Allergen 37
MAP 33
Efalizumab 32
Efalizumab 32
Pimecrolimus 32
ABC 31
Acyclovir 31
CTX 30
Leaf 29
Finasteride 28
Diphenhydramine 27
Alefacept 26
Fluconazole 25
Bexarotene 23
Doxycycline 23
EE2 23
L-tyrosine 22
Ipilimumab 22
Lamisil 22
Lamisil 22
NADH 22
Prednisolone 21
Botox 21
ENT 20
nitroglycerin 19
KGF 19
Sorafenib 19
Glutathione 19
Paraffin 18
CPO 18
Imatinib 18
citric acid 18
Gleevec 18
ICI 17
CaCl2 17
IFN-beta 17
CaCl2 17
CaCl2 17
lactose 17
PDL 17
Asthma 16
Aloe 16
G-CSF 16
Prednisone 15
more...
Enzyme
mitogen-activated protein kinase 541
tyrosinase 537
ERK 449
collagenase 368
trypsin 327
peroxidase 265
reverse transcriptase 253
calcineurin 242
protein kinase C 213
transglutaminase 199
protein kinase 185
catalase 168
ATPase 155
superoxide dismutase 152
phosphodiesterase 152
focal adhesion kinase 151
MEK 141
tryptase 129
alkaline phosphatase 127
adenylate cyclase 110
caspase-3 104
lactate dehydrogenase 103
plasmin 101
DCF 101
luciferase 100
urokinase-type plasminogen activator 93
elastase 92
hyaluronidase 85
ornithine decarboxylase 82
lysozyme 81
hyaluronidase 71
lipoxygenase 69
RNA polymerase 65
beta-galactosidase 64
phospholipase C 63
acid phosphatase 63
glutathione peroxidase 61
endonuclease 60
APC 60
MMP-3 59
lipase 59
phospholipase A2 58
chymase 57
CD10 54
RNase 54
RNase 54
kallikrein 52
transcriptase 50
granzyme B 47
caspase-1 46
neutrophil elastase 45
ACE 44
type III procollagen 42
interstitial collagenase 42
thrombin 41
KLK7 41
alanine aminotransferase 41
proteasome 40
neuraminidase 39
matrix metalloproteinase 2 39
beta-glucuronidase 38
DNA polymerase 37
pepsin 37
matrix metalloproteinase 9 35
glucose-6-phosphate dehydrogenase 34
glutathione S-transferase 34
cathepsin D 34
uroporphyrinogen decarboxylase 34
chymotrypsin 33
aspartate aminotransferase 33
xanthine oxidase 32
arylsulfatase 32
ferrochelatase 32
MMP 31
tissue plasminogen activator 30
gamma-glutamyl transpeptidase 29
phosphatidylinositol 3-kinase 29
botulinum neurotoxin 28
glutathione reductase 27
papain 27
more...
Compound
Dec 17342
Clin 17167
DNA 3312
water 1492
calcium 1231
sodium 815
oxygen 764
retinoic acid 692
sulfate 574
acetate 570
TNF 499
zinc 462
His 454
vitamin D 397
CO2 397
hyaluronic acid 361
phosphate 360
potassium 328
nickel 307
tyrosine 286
BMC 271
glucose 271
salt 238
nitrogen 230
serine 227
iodine 225
silver 220
iron 214
urea 205
salicylic acid 205
leucine 203
arginine 203
ethanol 196
hydrogen 182
cAMP 177
AMP 177
SDS 170
Collagen 169
cysteine 168
pyrimidine 165
pyrimidine 164
retinol 162
nitric oxide 160
hydroquinone 153
acetone 149
Cyclosporine 141
copper 140
aluminum 137
galactose 130
hydroxide 126
lysine 122
Methotrexate 122
KOH 122
azelaic acid 122
methionine 121
MOP 119
DSS 113
proline 111
nicotinamide 108
Phe 108
MEK 106
phenol 106
formaldehyde 105
Etretinate 105
ATP 103
FK506 101
PGE2 100
creatinine 99
Keratin 98
tryptophan 95
TCA 94
Histamine 92
H2O2 89
propylene glycol 89
bromide 86
EDTA 85
glycerol 85
EDTA 85
SCC 85
formaldehyde 84
more...