Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D01061 (CPT-11)
 1,899 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
topoisomerase I 0.008
carboxylesterase 0.002
CES2 0.002
DNA topoisomerase I 0.002
CES1 0.001
cholesteryl ester hydrolase 0.001
CPT 0.001
D14S1461E 0.001
CES1A1 0.000
canalicular multispecific organic anion transporter 0.000
TXL 0.000
UGT1A1 0.000
CEA 0.000
TSC1 protein 0.000
HB1 0.000
dihydropyrimidine dehydrogenase 0.000
NB3 0.000
CLCN4 0.000
DNA topoisomerase 0.000
type I DNA topoisomerase 0.000
POR1 0.000
CES3 0.000
CAC-1 0.000
colon carcinoma 0.000
PSN1 0.000
IRIS 0.000
ABCG2 0.000
LY6D 0.000
N-MYC 0.000
UGT1A 0.000
thymidylate synthase 0.000
DRG1 0.000
UDP-glucuronosyltransferase 1A1 0.000
Carboxylesterase 0.000
intestine, liver 0.000
breast cancer resistance protein 0.000
DEXI 0.000
UDP-glucuronosyltransferase 0.000
BCRP 0.000
KCP 0.000
MST 0.000
PSK 0.000
type I transmembrane receptor 0.000
P-glycoprotein 0.000
GS-X 0.000
beta-tubulin protein 0.000
multidrug resistance-associated protein 0.000
ADM 0.000
ABCC1 0.000
NPRL2 0.000
pT3 0.000
arylacetamide deacetylase 0.000
glucuronosyltransferase 0.000
HAI 0.000
MTD 0.000
SLCO1B1 0.000
NPC 0.000
Multidrug resistance protein 1 0.000
APC 0.000
1A1 0.000
MTX 0.000
hMLH1 0.000
Stomatin-like protein 2 0.000
GEM 0.000
RSN 0.000
MRP 0.000
FK506-binding protein 12 0.000
CLIC4 0.000
TOP1 0.000
CDHP 0.000
PMC 0.000
CPA 0.000
NIPA 0.000
multidrug resistance protein 2 0.000
L-type amino acid transporter 1 0.000
OTUB1 0.000
beta-glucuronidase 0.000
UGT1 0.000
ICRF 0.000
FGFR-4 0.000
more...
Disease
recurrent gastric cancer 0.002
colorectal cancer 0.001
neutropenia 0.001
colon cancer 0.001
gastric cancer 0.001
liver metastases 0.001
Carcinomatous peritonitis 0.001
recurrent colon cancer 0.000
refractory testicular cancer 0.000
cancer 0.000
tumor 0.000
leukopenia 0.000
recurrent gallbladder cancer 0.000
rectal cancer 0.000
RHN 0.000
recurrent pancreatic cancer 0.000
small cell lung cancer 0.000
recurrent rectal cancer 0.000
metastases 0.000
Overwhelming post-splenectomy infection 0.000
childhood ependymoma 0.000
ovarian carcinosarcoma 0.000
lung cancer 0.000
stage III colorectal cancer 0.000
non-small cell lung cancer 0.000
Krukenberg tumor 0.000
myelosuppression 0.000
lung metastases 0.000
metastatic colon cancer 0.000
gastric cancer stage 0.000
neuroendocrine carcinoma 0.000
carcinoma 0.000
recurrent esophageal cancer 0.000
stage IV NSCLC 0.000
GUD 0.000
stage III NSCLC 0.000
adenocarcinoma 0.000
Small cell carcinoma 0.000
stage III colon cancer 0.000
stage IV colorectal cancer 0.000
measurable disease 0.000
ovarian cancer 0.000
metastatic gastric cancer 0.000
tumor growth 0.000
childhood rhabdomyosarcoma 0.000
recurrent cervical cancer 0.000
Large cell neuroendocrine carcinoma 0.000
recurrent ovarian cancer 0.000
pancreatic cancer 0.000
PMC 0.000
TAM 0.000
ovarian mucinous cystadenocarcinoma 0.000
metastatic pancreatic cancer 0.000
solid tumor 0.000
recurrent breast cancer 0.000
APC 0.000
stage II colorectal cancer 0.000
Dukes 0.000
metastatic esophageal cancer 0.000
gastrointestinal cancer 0.000
Gastric Cancer 0.000
lung carcinoma 0.000
Skin toxicity 0.000
large cell lung cancer 0.000
NPC 0.000
carcinomatosis 0.000
thrombocytopenia 0.000
DMAC 0.000
TAS 0.000
stage IIIA NSCLC 0.000
stage III ovarian cancer 0.000
TCO 0.000
Chemoradiation 0.000
primary tumor 0.000
glioma 0.000
metastatic rectal cancer 0.000
clear cell carcinoma 0.000
Trousseau's syndrome 0.000
limited-stage small cell lung cancer 0.000
biliary tract cancer 0.000
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Symptom
diarrhea 0.001
Severe diarrhea 0.000
nausea 0.000
anorexia 0.000
vomiting 0.000
anal pain 0.000
abdominal fullness 0.000
asthenia 0.000
nausea and vomiting 0.000
abdominal cramps 0.000
epigastric pain 0.000
fatigue 0.000
abdominal pain 0.000
ataxic gait 0.000
dyspnea 0.000
Gastrointestinal symptoms 0.000
limb pain 0.000
hip pain 0.000
constipation 0.000
discomfort 0.000
cachexia 0.000
Ill 0.000
dysesthesia 0.000
discomfort 0.000
decreased appetite 0.000
night sweats 0.000
dental pain 0.000
HSA 0.000
nasal discharge 0.000
colic 0.000
flushing 0.000
bloating 0.000
abdominal discomfort 0.000
chest pain 0.000
cough 0.000
rhinorrhea 0.000
numbness 0.000
pain 0.000
cancer pain 0.000
exertional dyspnea 0.000
dysarthria 0.000
hemiplegia 0.000
myoclonus 0.000
dizziness 0.000
paresthesia 0.000
back pain 0.000
lethargy 0.000
arthralgia 0.000
regurgitation 0.000
weakness 0.000
splenomegaly 0.000
low back pain 0.000
insomnia 0.000
collapse 0.000
sleepiness 0.000
exhaustion 0.000
headache 0.000
hypothermia 0.000
tremor 0.000
angina 0.000
anesthesia 0.000
Drug
CPT-11 0.999
Irinotecan 0.050
Gemzar 0.001
Paraplatin 0.001
Taxotere 0.001
Isovorin 0.001
Leucovorin 0.001
Exatecan mesylate 0.001
Navelbine 0.000
Lasofoxifene tartrate 0.000
CXM-AX 0.000
Telavancin hydrochloride 0.000
Lumiliximab 0.000
Sobuzoxane 0.000
Apaziquone 0.000
Succinobucol 0.000
Vinorelbine 0.000
Focalin 0.000
Eniluracil 0.000
Eniluracil 0.000
TTC 0.000
Temodal 0.000
Docetaxel 0.000
Oxaliplatin 0.000
GEO 0.000
Indisulam 0.000
Bazedoxifene acetate 0.000
Taxol 0.000
Xeloda 0.000
Indiplon 0.000
Alimta 0.000
Metreleptin 0.000
Edatrexate 0.000
Peginterferon alfa-2b 0.000
Peginterferon alfa-2b 0.000
Epidoxorubicin 0.000
Aliskiren fumarate 0.000
CPDX-PR 0.000
Uzel 0.000
Duloxetine hydrochloride 0.000
Retapamulin 0.000
Escitalopram oxalate 0.000
Pemetrexed disodium 0.000
Teduglutide 0.000
Chlorpheniramine maleate 0.000
Lonafarnib 0.000
Methyl aminolevulinate 0.000
Demerol 0.000
Pemetrexed 0.000
Tarceva 0.000
ADM 0.000
Genasense 0.000
Gefitinib 0.000
Cetuximab 0.000
Gadoteridol 0.000
Gliadel 0.000
Demerol 0.000
Amoxapine 0.000
VCR 0.000
Alefacept 0.000
Drotrecogin alfa 0.000
Drotrecogin alfa 0.000
Telbivudine 0.000
Ixabepilone 0.000
Vorinostat 0.000
Tirapazamine 0.000
Ciclesonide 0.000
Diamminedichloroplatinum 0.000
Zinc sulfate 0.000
Pegasys 0.000
Zinc sulfate 0.000
Teniposide 0.000
Perphenazine 0.000
G-CSF 0.000
Aricept 0.000
Bevacizumab 0.000
Gemifloxacin 0.000
Dutasteride 0.000
Pimecrolimus 0.000
Vindesine 0.000
more...
Enzyme
carboxylesterase 0.002
CPT 0.001
topoisomerase 0.001
CPT 0.000
topoisomerase 0.000
CPT 0.000
dihydropyrimidine dehydrogenase 0.000
dihydropyrimidine dehydrogenase 0.000
UDP-glucuronosyltransferase 0.000
thymidylate synthase 0.000
P-glycoprotein 0.000
MTD 0.000
beta-glucuronidase 0.000
APC 0.000
CYP3A4 0.000
deoxyguanosine kinase 0.000
folylpolyglutamate synthetase 0.000
caspase-3 0.000
deoxycytidine kinase 0.000
MDR 0.000
carboxypeptidase G2 0.000
cytosine deaminase 0.000
sphingomyelin synthase 0.000
PARP 0.000
thymidine phosphorylase 0.000
ERK 0.000
CPM 0.000
acetylcholinesterase 0.000
choline oxidase 0.000
CPN 0.000
thromboxane synthase 0.000
CCS 0.000
cholinesterase 0.000
gamma-glutamylcysteine synthetase 0.000
AGT 0.000
ubiquitin-protein ligase 0.000
caspase-9 0.000
TSP-1 0.000
DCF 0.000
caspase-7 0.000
trehalase 0.000
caspase-7 0.000
NQO1 0.000
caspase-1 0.000
caspase-8 0.000
thymidine kinase 0.000
ribonucleotide reductase 0.000
ribonucleotide reductase 0.000
transpeptidase 0.000
polo-like kinase 1 0.000
Alternating 0.000
GSK 0.000
lactase 0.000
DNA methyltransferase 0.000
ADH 0.000
glutathione S-transferase 0.000
proteasome 0.000
enolase 0.000
MMP 0.000
MEK 0.000
reverse transcriptase 0.000
deaminase 0.000
dihydrofolate reductase 0.000
luciferase 0.000
AMPK 0.000
ornithine decarboxylase 0.000
tyrosine hydroxylase 0.000
lactate dehydrogenase 0.000
carbonic anhydrase 0.000
mitogen-activated protein kinase 0.000
protein kinase C 0.000
cdc2 0.000
gamma-glutamyl transpeptidase 0.000
alcohol dehydrogenase 0.000
urokinase-type plasminogen activator 0.000
chymotrypsin 0.000
focal adhesion kinase 0.000
phosphatidylinositol 3-kinase 0.000
AMPK 0.000
AMP-activated protein kinase 0.000
more...
Compound
CPT-11 0.990
SN-38 0.094
5-aminopentanoic acid 0.003
5-FU 0.003
Camptothecin 0.001
Camptothecin 0.001
Camptothecin 0.001
Leucovorin 0.001
ZD1694 0.001
Topotecan 0.001
CPT 0.001
CPT 0.000
VP-16 0.000
Topotecan 0.000
folinic acid 0.000
Methylselenocysteine 0.000
Dibromodulcitol 0.000
6-Mercaptopurine riboside 0.000
CBDCA 0.000
CBDCA 0.000
Nedaplatin 0.000
MMC 0.000
Gemcitabine 0.000
Gemcitabine 0.000
ACNU 0.000
DDP 0.000
benzil 0.000
Rhizoxin 0.000
Paclitaxel 0.000
R-11 0.000
Capecitabine 0.000
Sulfobromophthalein 0.000
bis(2-chloroethyl) 0.000
Lubiprostone 0.000
bis(2-chloroethyl) 0.000
2-chloroacetamide 0.000
MTX 0.000
VM-26 0.000
Docetaxel 0.000
FUDR 0.000
DOC 0.000
Androstane 0.000
Perillyl alcohol 0.000
Perillyl alcohol 0.000
5-formyltetrahydrofolate 0.000
bis(2-chloroethyl) 0.000
CPA 0.000
Loperamide 0.000
ETH 0.000
BEP 0.000
Methotrexate 0.000
Emtricitabine 0.000
CPA 0.000
cephalotaxine 0.000
CPA 0.000
cephalotaxine 0.000
Trifluorothymidine 0.000
Homoharringtonine 0.000
D 3 0.000
CPA 0.000
Zinc sulfate 0.000
Pregnane 0.000
Tegafur 0.000
DNA 0.000
2-methylpyridine 0.000
Asiatic acid 0.000
MTT 0.000
1-indanone 0.000
1-indanone 0.000
m-AMSA 0.000
A 71 0.000
piperidine 0.000
piperidine 0.000
Thymoquinone 0.000
Tegafur 0.000
Reserpine 0.000
quinoline 0.000
quinoline 0.000
TMQ 0.000
MTA 0.000
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