Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D01061 (CPT-11)
1,899 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
topoisomerase I 0.008
carboxylesterase 0.002
CES2 0.002
DNA topoisomerase I 0.002
CES1 0.001
cholesteryl ester hydrolase 0.001
CPT 0.001
D14S1461E 0.001
CES1A1 0.000
canalicular multispecific organic anion transporter 0.000
TXL 0.000
UGT1A1 0.000
CEA 0.000
TSC1 protein 0.000
HB1 0.000
dihydropyrimidine dehydrogenase 0.000
NB3 0.000
CLCN4 0.000
DNA topoisomerase 0.000
type I DNA topoisomerase 0.000
POR1 0.000
CAC-1 0.000
CES3 0.000
colon carcinoma 0.000
PSN1 0.000
IRIS 0.000
ABCG2 0.000
N-MYC 0.000
LY6D 0.000
UGT1A 0.000
thymidylate synthase 0.000
DRG1 0.000
UDP-glucuronosyltransferase 1A1 0.000
Carboxylesterase 0.000
intestine, liver 0.000
breast cancer resistance protein 0.000
DEXI 0.000
UDP-glucuronosyltransferase 0.000
BCRP 0.000
KCP 0.000
more...
Disease
recurrent gastric cancer 0.002
colorectal cancer 0.001
neutropenia 0.001
colon cancer 0.001
gastric cancer 0.001
liver metastases 0.001
Carcinomatous peritonitis 0.001
recurrent colon cancer 0.000
refractory testicular cancer 0.000
cancer 0.000
tumor 0.000
leukopenia 0.000
recurrent gallbladder cancer 0.000
rectal cancer 0.000
recurrent pancreatic cancer 0.000
RHN 0.000
small cell lung cancer 0.000
recurrent rectal cancer 0.000
metastases 0.000
Overwhelming post-splenectomy infection 0.000
childhood ependymoma 0.000
ovarian carcinosarcoma 0.000
lung cancer 0.000
stage III colorectal cancer 0.000
non-small cell lung cancer 0.000
Krukenberg tumor 0.000
myelosuppression 0.000
lung metastases 0.000
metastatic colon cancer 0.000
gastric cancer stage 0.000
neuroendocrine carcinoma 0.000
carcinoma 0.000
recurrent esophageal cancer 0.000
stage IV NSCLC 0.000
GUD 0.000
stage III NSCLC 0.000
adenocarcinoma 0.000
Small cell carcinoma 0.000
stage III colon cancer 0.000
stage IV colorectal cancer 0.000
more...
Symptom
diarrhea 0.001
Severe diarrhea 0.000
nausea 0.000
anorexia 0.000
vomiting 0.000
anal pain 0.000
abdominal fullness 0.000
asthenia 0.000
nausea and vomiting 0.000
abdominal cramps 0.000
epigastric pain 0.000
fatigue 0.000
abdominal pain 0.000
ataxic gait 0.000
dyspnea 0.000
Gastrointestinal symptoms 0.000
limb pain 0.000
hip pain 0.000
constipation 0.000
discomfort 0.000
cachexia 0.000
Ill 0.000
dysesthesia 0.000
discomfort 0.000
decreased appetite 0.000
night sweats 0.000
dental pain 0.000
HSA 0.000
nasal discharge 0.000
colic 0.000
flushing 0.000
bloating 0.000
abdominal discomfort 0.000
chest pain 0.000
cough 0.000
rhinorrhea 0.000
numbness 0.000
pain 0.000
cancer pain 0.000
exertional dyspnea 0.000
more...
Drug
CPT-11 0.999
Irinotecan 0.050
Gemzar 0.001
Paraplatin 0.001
Taxotere 0.001
Isovorin 0.001
Leucovorin 0.001
Exatecan mesylate 0.001
Navelbine 0.000
Lasofoxifene tartrate 0.000
CXM-AX 0.000
Telavancin hydrochloride 0.000
Sobuzoxane 0.000
Lumiliximab 0.000
Apaziquone 0.000
Succinobucol 0.000
Vinorelbine 0.000
Focalin 0.000
Eniluracil 0.000
Eniluracil 0.000
TTC 0.000
Temodal 0.000
Docetaxel 0.000
Oxaliplatin 0.000
GEO 0.000
Indisulam 0.000
Bazedoxifene acetate 0.000
Taxol 0.000
Xeloda 0.000
Indiplon 0.000
Alimta 0.000
Metreleptin 0.000
Edatrexate 0.000
Peginterferon alfa-2b 0.000
Peginterferon alfa-2b 0.000
Epidoxorubicin 0.000
Aliskiren fumarate 0.000
CPDX-PR 0.000
Uzel 0.000
Duloxetine hydrochloride 0.000
more...
Enzyme
carboxylesterase 0.002
CPT 0.001
topoisomerase 0.001
CPT 0.000
topoisomerase 0.000
CPT 0.000
dihydropyrimidine dehydrogenase 0.000
dihydropyrimidine dehydrogenase 0.000
UDP-glucuronosyltransferase 0.000
thymidylate synthase 0.000
P-glycoprotein 0.000
MTD 0.000
beta-glucuronidase 0.000
APC 0.000
CYP3A4 0.000
deoxyguanosine kinase 0.000
folylpolyglutamate synthetase 0.000
caspase-3 0.000
deoxycytidine kinase 0.000
MDR 0.000
carboxypeptidase G2 0.000
cytosine deaminase 0.000
sphingomyelin synthase 0.000
PARP 0.000
thymidine phosphorylase 0.000
ERK 0.000
CPM 0.000
acetylcholinesterase 0.000
choline oxidase 0.000
CPN 0.000
thromboxane synthase 0.000
CCS 0.000
cholinesterase 0.000
gamma-glutamylcysteine synthetase 0.000
AGT 0.000
ubiquitin-protein ligase 0.000
caspase-9 0.000
TSP-1 0.000
DCF 0.000
caspase-7 0.000
more...
Compound
CPT-11 0.990
SN-38 0.094
5-aminopentanoic acid 0.003
5-FU 0.003
Camptothecin 0.001
Camptothecin 0.001
Camptothecin 0.001
Leucovorin 0.001
ZD1694 0.001
Topotecan 0.001
CPT 0.001
CPT 0.000
VP-16 0.000
Topotecan 0.000
folinic acid 0.000
Methylselenocysteine 0.000
Dibromodulcitol 0.000
6-Mercaptopurine riboside 0.000
CBDCA 0.000
CBDCA 0.000
Nedaplatin 0.000
MMC 0.000
Gemcitabine 0.000
Gemcitabine 0.000
ACNU 0.000
DDP 0.000
benzil 0.000
Rhizoxin 0.000
Paclitaxel 0.000
R-11 0.000
Capecitabine 0.000
Sulfobromophthalein 0.000
bis(2-chloroethyl) 0.000
Lubiprostone 0.000
bis(2-chloroethyl) 0.000
2-chloroacetamide 0.000
MTX 0.000
VM-26 0.000
Docetaxel 0.000
FUDR 0.000
more...