Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D00710 (Sodium valproate)
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Human Gene/Protein
KIAA2022 12.5
Aldehyde reductase 11.2
class I histone deacetylase 10.8
NB-3 10.2
claudin 5 10.2
GABA transaminase 9.8
MARCKS protein 9.7
ATP1A2 9.3
NPO 9.2
succinic semialdehyde dehydrogenase 8.9
LPH 8.4
aldolase B 8.3
ABCE1 8.3
UBE3A 8.0
DNA polymerase gamma 8.0
Aldose reductase 7.9
EOS 7.8
aldehyde reductase 7.7
regucalcin 7.7
2-oxoglutarate dehydrogenase 7.6
soluble epoxide hydrolase 7.6
ACH 7.5
histone deacetylase 1 7.5
SCN1A 7.3
alpha-ketoglutarate dehydrogenase 7.3
PME 7.3
ICAM-3 7.1
ATA 7.0
cytosolic phospholipase A2 6.9
interleukin 12 6.9
tryptophan hydroxylase 6.9
brain protein 6.8
GAD 6.8
lipoamide dehydrogenase 6.7
TET2 6.6
IDO 6.6
histone deacetylase 6.6
GABA 6.5
MIF 6.4
MT-2 6.3
more...
Disease
Fetal anticonvulsant syndrome 16.6
Acute mania 14.3
chronic chorea 14.0
Proximal myopathy 13.6
Photosensitive epilepsy 13.4
Lichenoid dermatitis 13.1
fetal valproate syndrome 12.5
Catamenial epilepsy 11.8
Carnitine deficiency 11.4
Drug-induced hypersensitivity syndrome 11.0
petit mal 10.3
erythrodermia 9.9
grand mal epilepsy 9.7
Meige syndrome 9.5
juvenile myoclonic epilepsy 9.5
Gingival overgrowth 9.3
reflex epilepsy 9.1
somatostatinoma 9.0
hepatic porphyria 8.7
Sydenham's chorea 8.6
Landau-Kleffner syndrome 8.3
generalized seizure 7.9
Lennox-Gastaut syndrome 7.9
EOS 7.8
EOS 7.8
Nelson 7.6
ADD 7.6
PME 7.5
hemiplegic migraine 7.5
mania 7.3
tardive dyskinesia 7.3
abnormal involuntary movements 7.3
myoclonus epilepsy 7.1
Lennox-Gastaut syndrome 7.1
delirium tremens 7.1
monocytic leukemia 7.0
epilepsy 7.0
Fanconi syndrome 6.9
Reye's syndrome 6.8
Cholangiocarcinoma 6.8
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Symptom
asterixis 8.9
pedal edema 8.9
tonic-clonic seizure 8.6
myoclonus 8.0
abnormal gait 7.5
clonus 7.1
enuresis 6.9
seizures 6.7
Sedation 6.2
lethargy 6.1
photophobia 6.0
sleepiness 6.0
torticollis 5.9
twitching 5.6
chorea 5.6
tremor 5.4
ataxia 5.2
HSA 5.1
acute abdomen 5.0
vertigo 4.8
agitation 4.6
nausea 4.4
dizziness 4.4
hyperoxia 4.3
vomiting 4.2
headache 4.1
tinnitus 3.9
weakness 3.4
nausea and vomiting 3.4
insomnia 3.2
anorexia 2.9
analgesia 1.8
diarrhea 1.8
pain 1.4
fatigue 0.9
Drug
Sodium valproate 16.6
Valproic Acid 14.7
Valpromide 13.9
Valpromide 13.6
Phenobarbital sodium 12.4
DPA 11.0
Lioresal 11.0
Rufinamide 10.7
Keppra 10.6
Dilantin 10.3
Syrup 9.8
Span 60 9.3
Phenytoin 9.0
Ritalin 8.2
Sulpiride 7.4
Kainic acid 7.3
MRC 4.9
CaCl2 4.0
CaCl2 4.0
CaCl2 3.9
Spectrum 3.7
Monit 3.5
CSF 3.3
Gel 2.7
vitamin E 2.5
Leaf 2.2
NADH 2.2
IL-2 1.8
lysine 0.8
Dermatol 0.2
Enzyme
GABA transaminase 9.5
succinic semialdehyde dehydrogenase 8.4
caspase-11 8.2
caspase-11 8.1
PME 8.1
aldehyde reductase 7.6
aldehyde reductase 7.6
aldehyde reductase 7.6
alpha-ketoglutarate dehydrogenase 7.3
tryptophan hydroxylase 6.8
soluble epoxide hydrolase 6.5
pyruvate carboxylase 6.0
pyruvate dehydrogenase 5.8
pyruvate dehydrogenase 5.8
glutamate decarboxylase 5.5
pyruvate dehydrogenase 5.2
diaphorase 5.2
aldose reductase 4.9
succinate dehydrogenase 4.6
aspartate aminotransferase 4.5
glutamate dehydrogenase 4.5
glutamate dehydrogenase 4.5
glutamate dehydrogenase 4.5
citrate synthase 4.5
malate dehydrogenase 4.4
CPR 4.2
AST 4.0
ATP synthase 3.8
alanine aminotransferase 3.5
alcohol dehydrogenase 3.4
monoamine oxidase 3.2
glutathione peroxidase 3.2
alkaline phosphatase 3.1
P-glycoprotein 2.9
PARP 2.9
beta-galactosidase 2.8
superoxide dismutase 2.8
tyrosine hydroxylase 2.8
DNA polymerase 2.5
caspase-3 2.5
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Compound
Trimethadione 11.4
Ethosuximide 11.2
2-ethylhexanoic acid 10.1
2-ethylhexanoic acid 10.1
2-ethylhexanoic acid 10.1
2-ethylhexanoic acid 9.7
Lithium chloride 9.5
Clonazepam 9.4
Valproic acid 9.3
Picrotoxin 9.2
Picrotoxin 9.2
11-dehydro-thromboxane 9.0
Valproic acid 8.9
Bepridil 8.9
Nitrazepam 8.9
Diallyl 8.8
Levetiracetam 8.6
Cyproheptadine 8.6
Ritalin 8.4
DPH 8.1
Lamotrigine 8.1
EOS 7.8
Kainic acid 7.3
Kainic acid 7.3
ACNU 7.3
Neurotol 7.1
Apigenin 7.1
Sulforaphane 7.0
Muscimol 6.9
Acetazolamide 6.9
L-carnitine 6.7
butyric acid 6.6
gamma-aminobutyric acid 6.6
octanoic acid 6.6
octanoic acid 6.6
octanoic acid 6.5
Haloperidol 6.5
octanoic acid 6.5
DPA 6.5
DPA 6.5
more...