Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: KEGG:D00670 (Aricept)
 106 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Dermatopontin 11.8
PPB 11.6
ADAS 10.5
ENA 10.2
Cholinesterase 9.7
acetylcholinesterase 9.2
TAK 9.0
Choline acetyltransferase 8.9
MTP 8.9
calcium/calmodulin-dependent protein kinase II 8.8
muscarinic acetylcholine receptor 8.8
butyrylcholinesterase 8.7
version 1 8.3
intestine, liver 8.1
DNA polymerase beta 8.1
APP 8.0
version 3 8.0
Glycogen synthase 7.9
cAMP response element binding protein 7.8
PS1 7.8
LC3B 7.8
amyloid protein 7.7
RAGE 7.7
pro-apoptotic protein 7.6
ABCA1 7.6
AChE 7.5
HMGB1 7.5
brain-derived 7.5
WIN 7.5
ADL 7.4
carboxylesterase 7.4
DCX 7.1
amyloid precursor protein 7.1
5-HT3 receptor 7.0
Beclin-1 7.0
neural cell adhesion molecule 6.9
anti-apoptotic protein 6.7
CAT 6.6
FRAP 6.6
GSK 6.6
synaptophysin 6.6
muscarinic receptor 6.5
VIP 6.4
glyceraldehyde-3-phosphate dehydrogenase 6.1
p62 5.9
PDB 5.9
amyloid beta 5.8
GABA(A) receptor 5.8
acetylcholine receptor 5.7
phosphorylating 5.7
choline acetyltransferase 5.6
DSC 5.5
ATR 5.5
esterase 5.4
AMP-activated protein kinase 5.3
apolipoprotein E 5.3
antioxidant enzyme 5.2
chymotrypsin 4.9
NHS 4.8
CA3 4.8
C18 4.7
CA1 4.6
proliferating cell nuclear antigen 4.5
p65 4.4
caspase-3 4.3
GABA 4.1
SOD 3.9
somatostatin 3.8
ANOVA 3.7
PI3K 3.7
mTOR 3.5
lactate dehydrogenase 3.5
hole 3.3
growth hormone 3.3
microsomal 3.2
Mem 3.2
Bcl-2 3.2
olfactory 3.0
GSH 3.0
histone 2.7
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Disease
PPB 11.4
Wernicke's aphasia 10.7
global aphasia 10.6
Vascular dementia 9.6
HPC 8.3
Tongue 8.3
Alzheimer's disease 7.8
Dementia with Lewy bodies 7.5
AGA 7.4
Robinson 7.3
ICH 7.0
cognitive impairment 6.9
hairy cell leukemia 6.8
dementia 6.7
aphasia 6.5
memory impairment 6.4
ADHD 6.0
amnesia 5.8
sleep disturbances 5.8
PDB 5.5
NHS 4.8
Autism 4.5
Down syndrome 4.4
B-cell lymphoma 4.2
cerebral ischemia 4.1
Best 4.1
plaque 4.1
chronic disease 4.0
colon cancer 3.4
psychosis 3.4
fits 3.3
autism 3.2
GSH 3.0
multiple sclerosis 2.8
SEM 2.7
stroke 2.6
schizophrenia 2.3
Parkinson's disease 2.3
depression 0.8
Symptom
muscle cramps 8.4
fasciculation 7.9
bitter taste 7.7
memory loss 7.4
hypothermia 5.1
syncope 5.0
nausea and vomiting 5.0
dizziness 5.0
constipation 4.9
insomnia 4.8
nausea 4.7
anorexia 4.4
diarrhea 4.4
vomiting 4.2
fatigue 2.5
headache 2.4
Drug
Aricept 18.2
Exelon 16.1
Exelon 16.0
Galantamine hydrobromide 15.9
Reminyl 15.8
Donepezil 15.5
Namenda 15.1
Cognex 14.6
DMAA 13.4
Seroquel 11.7
Adderall 10.9
Poloxamer 188 10.4
Prozac 10.2
THA 9.9
Ritalin 9.8
TAK 9.2
DFP 8.3
Scopolamine 7.9
CPT-11 7.3
Portal 6.2
nitroglycerin 5.1
Nephron 4.1
Enzyme
proteinase-3 9.8
cholinesterase 9.3
acetylcholinesterase 9.3
carboxylesterase 6.6
GSK 6.5
glyceraldehyde-3-phosphate dehydrogenase 6.1
glyceraldehyde-3-phosphate dehydrogenase 6.1
glyceraldehyde-3-phosphate dehydrogenase 6.0
glyceraldehyde-3-phosphate dehydrogenase 5.7
choline acetyltransferase 5.6
glyceraldehyde-3-phosphate dehydrogenase 5.5
complex I 5.1
caspase-3 4.7
AMP-activated protein kinase 4.5
DNA polymerase 4.1
catalase 4.0
lactate dehydrogenase 3.4
superoxide dismutase 3.4
luciferase 3.0
ATPase 2.2
Compound
C12H21N 18.2
C12H21N 18.2
C12H21N 18.2
C12H21N 18.2
C12H21N 18.2
C12H21N 18.2
C12H21N 18.2
C12H21N 18.2
C12H21N 18.2
Donepezil hydrochloride 18.1
5,10-dihydroindeno[1,2-b]indole 15.2
Remantadine 14.0
Rivastigmine 12.1
PAPP 12.1
EPB 12.1
Rimantadine 12.0
PAPP 11.9
Tropisetron 11.0
Tacrine 10.9
MPB 10.0
Ritalin 10.0
Naringin 9.9
01M 9.9
d-Amphetamine 9.4
Naringin 9.3
Caffeic acid 9.2
Quetiapine 9.2
Memantine 8.9
galanthamine 8.8
Nimodipine 8.6
HPC 8.4
HPC 8.4
Olanzapine 8.4
QNB 8.3
Glycogen synthase 8.0
hydroxycinnamic acid 7.4
CPT-11 7.3
SEE 6.9
CAT 6.6
CAT 6.6
ACh 6.6
piperidine 6.6
piperidine 6.6
Quercetin 6.6
CAT 6.5
DNP 6.5
Pluronic 6.4
PDB 6.3
2-hydroxyethyl 6.0
2-hydroxyethyl 6.0
2-hydroxyethyl 6.0
2-hydroxyethyl 6.0
2-hydroxyethyl 6.0
2-hydroxyethyl 6.0
2-hydroxyethyl 6.0
Hearts 5.9
Norepinephrine 5.8
2-hydroxyethyl 5.7
Lactate 5.5
quinoline 5.4
acridine 5.4
quinoline 5.4
Dopamine 5.1
isopropanol 5.0
Tris 4.9
phosphoric acid 4.9
homocysteine 4.7
hexane 4.3
NMDA 4.2
GABA 4.1
GABA 4.1
MDA 3.6
HCl 3.5
mercury 3.5
methanol 3.3
H2O2 3.3
MTT 3.2
acetonitrile 3.2
noradrenaline 3.2
benzene 3.2
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