Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D00670 (
Aricept
)
106
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
acetylcholinesterase
44
Sep
9
amyloid precursor protein
8
Mol
7
butyrylcholinesterase
5
APP
4
CAT
3
caspase-3
3
GABA
2
ATP
2
ENA
2
PPB
2
muscarinic acetylcholine receptor
2
muscarinic receptor
2
TAK
2
GSK
2
Cholinesterase
2
AChE
2
PS1
2
ADAS
2
more...
Disease
Alzheimer's disease
83
dementia
19
cognitive impairment
15
stroke
3
plaque
3
aphasia
2
PPB
2
ADHD
2
memory impairment
2
hairy cell leukemia
1
Wernicke's aphasia
1
Robinson
1
multiple sclerosis
1
Down syndrome
1
PDB
1
sleep disturbances
1
fits
1
Dementia with Lewy bodies
1
ICH
1
psychosis
1
more...
Symptom
diarrhea
4
vomiting
2
hypothermia
2
nausea
2
memory loss
2
fasciculation
1
constipation
1
anorexia
1
fatigue
1
insomnia
1
dizziness
1
nausea and vomiting
1
bitter taste
1
syncope
1
muscle cramps
1
headache
1
Drug
Aricept
106
Donepezil
85
Exelon
9
Exelon
8
Reminyl
6
DMAA
4
Namenda
4
Galantamine hydrobromide
4
THA
3
TAK
2
Cognex
2
nitroglycerin
1
Seroquel
1
DFP
1
Nephron
1
CPT-11
1
Ritalin
1
Poloxamer 188
1
Portal
1
Scopolamine
1
more...
Enzyme
acetylcholinesterase
59
cholinesterase
27
caspase-3
3
catalase
3
superoxide dismutase
2
GSK
2
lactate dehydrogenase
1
AMP-activated protein kinase
1
luciferase
1
glyceraldehyde-3-phosphate dehydrogenase
1
ATPase
1
glyceraldehyde-3-phosphate dehydrogenase
1
glyceraldehyde-3-phosphate dehydrogenase
1
complex I
1
glyceraldehyde-3-phosphate dehydrogenase
1
DNA polymerase
1
proteinase-3
1
glyceraldehyde-3-phosphate dehydrogenase
1
choline acetyltransferase
1
carboxylesterase
1
more...
Compound
Donepezil hydrochloride
31
water
13
Dec
8
Clin
4
oxygen
3
CAT
3
ACh
3
CAT
3
sodium
3
CAT
3
Rivastigmine
3
ethanol
2
Tacrine
2
ATP
2
GABA
2
GABA
2
phosphate
2
glucose
2
acetate
2
methanol
2
more...