Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D00558 (
Carbidopa
)
163
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
dopa decarboxylase
35
Sep
12
5-hydroxytryptamine
9
renin
5
CSF
5
Mol
5
OMD
4
prolactin
4
NSD
4
ATPase
4
atrial natriuretic peptide
3
tyrosine hydroxylase
3
albumin
3
catechol-O-methyltransferase
2
aryl hydrocarbon receptor
2
tyrosinase
2
ddc
2
Ah receptor
2
tryptophan hydroxylase
2
proximal tubule
2
more...
Disease
Parkinson's disease
48
dyskinesia
8
parkinsonism
6
cancer
5
tumor
5
melanoma
4
NSD
4
restless legs syndrome
4
depression
4
movement disorder
3
hypertension
3
hypoglycemia
3
hyperphenylalaninemia
3
Alzheimer's disease
2
prostate cancer
2
iron deficiency
2
abnormal involuntary movements
2
hyperprolactinemia
2
fits
2
schizophrenia
2
more...
Symptom
tremor
10
nausea
4
dystonia
4
bradykinesia
3
seizures
3
ataxia
3
sleepiness
3
hypotonia
3
pain
2
motor symptom
2
vomiting
2
analgesia
1
insomnia
1
Postural tremor
1
agitation
1
fatigue
1
apathy
1
muscle rigidity
1
chorea
1
spasticity
1
more...
Drug
Sinemet
163
Carbidopa
163
CSF
5
Sinemet
4
Sinemet
4
Benserazide
3
Indomethacin
3
Aldomet
1
Rotigotine
1
Isoniazid
1
Pramipexole
1
Apomorphine
1
Spectrum
1
Gel
1
Gabapentin
1
Ouabain
1
9-THC
1
CTRX
1
Methyldopa
1
Pramipexole
1
more...
Enzyme
DOPA decarboxylase
23
monoamine oxidase
7
renin
5
ATPase
5
tyrosine hydroxylase
3
GTP cyclohydrolase I
3
tryptophan hydroxylase
2
kynureninase
2
tyrosinase
2
aromatic L-amino acid decarboxylase
2
tyrosine decarboxylase
1
mu-calpain
1
m-calpain
1
prostaglandin synthetase
1
superoxide dismutase
1
tyrosine aminotransferase
1
dopamine beta-hydroxylase
1
kallikrein
1
tryptophan 2,3-dioxygenase
1
lactase
1
more...
Compound
L-DOPA
69
Clin
24
sodium
23
5-hydroxytryptophan
16
Dec
15
Dopamine
10
hydroxyindoleacetic acid
10
tyrosine
10
salt
8
5-HT
7
tryptophan
6
Dopa
6
tryptophan
6
tryptophan
6
tryptophan
6
aldosterone
5
Phe
5
neopterin
4
water
4
hydrazine
4
more...