KEGG:D00307 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: KEGG:D00307 (Doxycycline)
1,090 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
Sep	75
matrix metalloproteinase	63
MMP-9	42
MMP-2	39
Mol	36
collagen	35
MIC	27
transactivator	18
collagenase	14
cytokine	14
metalloproteinase	12
Pseudomonas	12
lipopolysaccharide	11
insulin	11
p53	11
TNF	10
elastin	9
She	9
IL-6	9
MMP	8
MMP-8	8
tumor necrosis factor	8
EPA	8
vascular endothelial growth factor	8
TNF-alpha	7
p38	7
ROS	7
LPS	6
inducible nitric oxide synthase	6
MAPK	6
gut	6
SDS	6
ATP	6
E-cadherin	6
MMP-13	6
catenin	5
CSF	5
tyrosine hydroxylase	5
osteogenic	5
kit	5
lymphoid	5
IL-8	5
MRI	5
caspase-3	5
brain-derived neurotrophic factor	5
ERK1	5
matrix metalloproteinase 2	5
MRSA	5
ANOVA	5
PLA	4
granulocyte	4
vascular endothelium	4
amyloid precursor protein	4
transcriptional activator	4
osteosarcoma	4
scratch	4
aspartate aminotransferase	4
polypeptide	4
MMP-3	4
endoplasmic reticulum	4
PI3K	4
tissue inhibitor of metalloproteinases	4
IL-1	4
TMP	4
interferon	4
Polymerase	4
SARS	4
GABA	3
focal adhesion kinase	3
MMP-1	3
CRP	3
transcriptional regulator	3
c-Jun	3
c-Myc	3
AKT	3
cage	3
albumin	3
neutrophil elastase	3
interleukin-6	3
TIMP-2	3

Disease
cancer	67
tumor	51
malaria	38
infectious diseases	35
Lyme disease	34
Mycoplasma	31
Chlamydia	31
breast cancer	22
Q fever	21
rash	21
periodontitis	19
Infection	19
syphilis	18
pneumonia	17
HIV	16
ehrlichiosis	16
brucellosis	16
leptospirosis	15
thrombocytopenia	13
plaque	13
hypertension	13
filariasis	12
worms	12
tumor growth	12
diabetes	11
carcinoma	11
urethritis	11
zoonosis	11
acne	11
pelvic inflammatory disease	11
cholera	10
arthritis	10
Mycobacterium	10
scrub typhus	10
typhus	10
osteoarthritis	10
rosacea	10
onchocerciasis	10
hepatitis	9
lymphadenopathy	9
anthrax	9
melanoma	9
rickettsiosis	9
sepsis	9
renal failure	9
gonococcal	9
influenza	9
sepsis	8
periodontal disease	8
STD	8
acne vulgaris	8
tuberculosis	8
endocarditis	8
Alzheimer's disease	8
Rocky Mountain spotted fever	7
carcinogenesis	7
bronchitis	7
anemia	7
Brucella melitensis	7
Wuchereria	7
spotted fever	7
meningitis	7
adenocarcinoma	7
ischemia	7
lung cancer	7
SEM	7
abdominal aortic aneurysm	6
Legionella	6
Mediterranean spotted fever	6
lymphogranuloma venereum	6
vasculitis	6
infertility	6
Infections	6
plague	6
cervicitis	6
cold	6
bacterial infection	6
Parkinson's disease	6
virus infection	6
skin disease	6

Enzyme
collagenase	16
mitogen-activated protein kinase	14
ERK	11
focal adhesion kinase	11
MMP	8
beta-lactamase	7
luciferase	7
aspartate aminotransferase	6
alanine aminotransferase	5
caspase-3	5
tyrosine hydroxylase	5
MMP-3	5
matrix metalloproteinase 9	4
calcineurin	4
MEK	4
elastase	4
neutrophil collagenase	4
neutrophil elastase	3
peroxidase	3
proteasome	3
catalase	3
alkaline phosphatase	3
beta-galactosidase	3
plasmin	3
protein kinase	3
matrix metalloproteinase 2	3
firefly luciferase	3
cdc2	2
caspase-9	2
P-glycoprotein	2
RNase III	2
cytochrome oxidase	2
MDR	2
topoisomerase	2
ATPase	2
GTP cyclohydrolase I	2
RNA polymerase	2
cathepsin G	2
NO synthase	2
topoisomerase	2
TdT	1
CYP3A4	1
arginase	1
ACE	1
CPT	1
beta-glucuronidase	1
citrate synthase	1
glutathione S-transferase	1
caspase-8	1
thrombin	1
calcium pump	1
DNA methyltransferase	1
AMPK	1
DNA ligase	1
acyl-CoA dehydrogenase	1
angiotensin-converting enzyme 2	1
DNA ligase	1
demethylase	1
TSP-1	1
SPC	1
porphobilinogen deaminase	1
xanthine oxidase	1
succinate dehydrogenase	1
cathepsin B	1
lysyl oxidase	1
lipoxygenase	1
enterokinase	1
superoxide dismutase	1
15-lipoxygenase	1
cathepsin K	1
IKK	1
cathepsin L	1
ECH	1
AMPK	1
purine nucleoside phosphorylase	1
ferrochelatase	1
endonuclease	1
lysozyme	1
glutathione peroxidase	1
NOS	1